APC/Fire™ 750 anti-mouse CD115 (CSF-1R) | BioLegend 135536 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Fire™ 750 anti-mouse CD115 (CSF-1R)

catalog :

135536

quantity :

100 μg

price :

352 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

AFS98

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 4

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:100; loading ...; fig e8c, e8d	Mastorakos P, Mihelson N, Luby M, Burks S, Johnson K, Hsia A, et al. Temporally distinct myeloid cell responses mediate damage and repair after cerebrovascular injury. Nat Neurosci. 2021;24:245-258 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Lund H, Pieber M, Parsa R, Han J, Grommisch D, Ewing E, et al. Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells. Nat Commun. 2018;9:4845 pubmed publisher
	Yang C, Chen F, Ren P, Lofchy L, Wan C, Shen J, et al. Delivery of a model lipophilic membrane cargo to bone marrow via cell-derived microparticles. J Control Release. 2020;326:324-334 pubmed publisher
	Stuart T, Butler A, Hoffman P, Hafemeister C, Papalexi E, Mauck W, et al. Comprehensive Integration of Single-Cell Data. Cell. 2019;: pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Cat # :

135536

Clone :

AFS98

Item :

APC/Fire™ 750 anti-mouse CD115 (CSF-1R)

Isotype :

Rat IgG2a, κ

Other Names :

CSF-1R, M-CSFR, c-fms

Size :

100 μg

Price (USD) :

352 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC_F750

Application Notes :

Additional reported applications (for the relevant formats) include: blocking of ligand binding^1. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays.It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115^4.;

more info or order :

BioLegend product webpage