APC/Cyanine7 anti-mouse CD115 (CSF-1R) | BioLegend 135531 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC/Cyanine7 anti-mouse CD115 (CSF-1R)

catalog :

135531

quantity :

25 μg

price :

147 USD

clonality :

monoclonal

host :

rat

conjugate :

APC/Cy7

clone name :

AFS98

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; 1:400; loading ...; fig 3s3c	Burfeind K, Zhu X, Norgard M, Levasseur P, Huisman C, Buenafe A, et al. Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer. elife. 2020;9: pubmed publisher
	Jassinskaja M, Pimková K, Arh N, Johansson E, Davoudi M, Pereira C, et al. Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells. Cell Rep. 2021;34:108894 pubmed publisher
	Winkler E, Shrihari S, Hykes B, Handley S, Andhey P, Huang Y, et al. The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling Axis. Cell. 2020;182:901-918.e18 pubmed publisher
	Chandran S, Schilke R, Blackburn C, Yurochko A, Mirza R, Scott R, et al. Lipin-1 Contributes to IL-4 Mediated Macrophage Polarization. Front Immunol. 2020;11:787 pubmed publisher
	Fukushima K, Satoh T, Sugihara F, Sato Y, Okamoto T, Mitsui Y, et al. Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis. Immunity. 2020;52:542-556.e13 pubmed publisher
	Moreau H, Blanch Mercader C, Attia R, Maurin M, Alraies Z, Sanséau D, et al. Macropinocytosis Overcomes Directional Bias in Dendritic Cells Due to Hydraulic Resistance and Facilitates Space Exploration. Dev Cell. 2019;: pubmed publisher
	Barnette D, Cahill T, Gunadasa Rohling M, Carr C, Freeman M, Riley P. iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction. JCI Insight. 2018;3: pubmed publisher
	Jaeger B, Donadieu J, Cognet C, Bernat C, OrdoÃ±ez Rueda D, Barlogis V, et al. Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis. J Exp Med. 2012;209:565-80 pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Flow Cytometry

Cat # :

135531

Clone :

AFS98

Item :

APC/Cyanine7 anti-mouse CD115 (CSF-1R)

Isotype :

Rat IgG2a, κ

Other Names :

CSF-1R, M-CSFR, c-fms

Size :

25 μg

Price (USD) :

147 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC_CYANINE7

Application Notes :

Additional reported applications (for the relevant formats) include: blocking of ligand binding 1 . The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays. It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115 4 .

more info or order :

BioLegend product webpage