PE/Dazzle™ 594 anti-mouse CD115 (CSF-1R) | BioLegend 135528 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Dazzle™ 594 anti-mouse CD115 (CSF-1R)

catalog :

135528

quantity :

100 μg

price :

370 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

AFS98

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; loading ...; fig s3a	Fahy N, Palomares Cabeza V, Lolli A, Witte Bouma J, Merino A, Ridwan Y, et al. Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model. Front Immunol. 2021;12:715267 pubmed publisher
flow cytometry; mouse; 1:200; loading ...; fig 1a	Wuggenig P, Kaya B, Melhem H, Ayata C, Hruz P, Sayan A, et al. Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice. Commun Biol. 2020;3:130 pubmed publisher
flow cytometry; mouse; 1:300; fig 5	Aryal B, Rotllan N, Araldi E, Ramírez C, He S, Chousterman B, et al. ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression. Nat Commun. 2016;7:12313 pubmed publisher
flow cytometry; human; loading ...; fig 2b	Gadd V, Patel P, Jose S, Horsfall L, Powell E, Irvine K. Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation. PLoS ONE. 2016;11:e0157771 pubmed publisher
flow cytometry; mouse; fig 3a	Stoilova B, Kowenz Leutz E, Scheller M, Leutz A. Lymphoid to myeloid cell trans-differentiation is determined by C/EBP? structure and post-translational modifications. PLoS ONE. 2013;8:e65169 pubmed publisher
	Katzmarski N, Domínguez Andrés J, Cirovic B, Renieris G, Ciarlo E, Le Roy D, et al. Transmission of trained immunity and heterologous resistance to infections across generations. Nat Immunol. 2021;22:1382-1390 pubmed publisher
	Bae S, Park P, Lee Y, Mun S, Giannopoulou E, Fujii T, et al. MYC-mediated early glycolysis negatively regulates proinflammatory responses by controlling IRF4 in inflammatory macrophages. Cell Rep. 2021;35:109264 pubmed publisher
	Seydoux E, Homad L, MacCamy A, Parks K, Hurlburt N, Jennewein M, et al. Analysis of a SARS-CoV-2-Infected Individual Reveals Development of Potent Neutralizing Antibodies with Limited Somatic Mutation. Immunity. 2020;53:98-105.e5 pubmed publisher
	Jaeger B, Donadieu J, Cognet C, Bernat C, OrdoÃ±ez Rueda D, Barlogis V, et al. Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis. J Exp Med. 2012;209:565-80 pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Flow Cytometry

Cat # :

135528

Clone :

AFS98

Item :

PE/Dazzle™ 594 anti-mouse CD115 (CSF-1R)

Isotype :

Rat IgG2a, κ

Other Names :

CSF-1R, M-CSFR, c-fms

Size :

100 μg

Price (USD) :

370 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PE_DZL594

Application Notes :

Additional reported applications (for the relevant formats) include: blocking of ligand binding 1 . The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays. It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115 4 .

more info or order :

BioLegend product webpage