PerCP/Cyanine5.5 anti-mouse CD115 (CSF-1R) | BioLegend 135525 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP/Cyanine5.5 anti-mouse CD115 (CSF-1R)

catalog :

135525

quantity :

25 μg

price :

124 USD

clonality :

monoclonal

host :

rat

conjugate :

PerCP/Cy5.5

clone name :

AFS98

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig s3f	Binnewies M, Mujal A, Pollack J, Combes A, Hardison E, Barry K, et al. Unleashing Type-2 Dendritic Cells to Drive Protective Antitumor CD4+ T Cell Immunity. Cell. 2019;177:556-571.e16 pubmed publisher
	Vanneste D, Bai Q, Hasan S, Peng W, Pirottin D, Schyns J, et al. MafB-restricted local monocyte proliferation precedes lung interstitial macrophage differentiation. Nat Immunol. 2023;24:827-840 pubmed publisher
	Wu Z, Thierry K, Bachy S, Zhang X, Gamradt P, Hernandez Vargas H, et al. Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer. EMBO Rep. 2023;24:e56524 pubmed publisher
	Meacham C, Jeffery E, Burgess R, Sivakumar C, Arora M, Stanley A, et al. Adiponectin receptors sustain haematopoietic stem cells throughout adulthood by protecting them from inflammation. Nat Cell Biol. 2022;24:697-707 pubmed publisher
	Li X, Wang H, Yu X, Saha G, Kalafati L, Ioannidis C, et al. Maladaptive innate immune training of myelopoiesis links inflammatory comorbidities. Cell. 2022;185:1709-1727.e18 pubmed publisher
	Ali S, Borin T, Piranlioglu R, Ara R, Lebedyeva I, Angara K, et al. Changes in the tumor microenvironment and outcome for TME-targeting therapy in glioblastoma: A pilot study. PLoS ONE. 2021;16:e0246646 pubmed publisher
	Ramakrishna C, Kujawski M, Chu H, Li L, Mazmanian S, CANTIN E. Bacteroides fragilis polysaccharide A induces IL-10 secreting B and T cells that prevent viral encephalitis. Nat Commun. 2019;10:2153 pubmed publisher
	Hilt Z, Pariser D, Ture S, Mohan A, Quijada P, Asante A, et al. Platelet-derived β2M regulates monocyte inflammatory responses. JCI Insight. 2019;: pubmed publisher
	Clemente Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis. Immunity. 2017;47:974-989.e8 pubmed publisher
	Hulsmans M, Clauss S, Xiao L, Aguirre A, King K, Hanley A, et al. Macrophages Facilitate Electrical Conduction in the Heart. Cell. 2017;169:510-522.e20 pubmed publisher
	Kotfis K, Zegan Barańska M, Szydłowski Ł, Zukowski M, Ely E. Methods of pain assessment in adult intensive care unit patients - Polish version of the CPOT (Critical Care Pain Observation Tool) and BPS (Behavioral Pain Scale). Anaesthesiol Intensive Ther. 2017;49:66-72 pubmed publisher
	Jaeger B, Donadieu J, Cognet C, Bernat C, OrdoÃ±ez Rueda D, Barlogis V, et al. Neutrophil depletion impairs natural killer cell maturation, function, and homeostasis. J Exp Med. 2012;209:565-80 pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Cat # :

135525

Clone :

AFS98

Item :

PerCP/Cyanine5.5 anti-mouse CD115 (CSF-1R)

Isotype :

Rat IgG2a, κ

Other Names :

CSF-1R, M-CSFR, c-fms

Size :

25 μg

Price (USD) :

124 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PERCP_CYANINE5.5

Application Notes :

Additional reported applications (for the relevant formats) include: blocking of ligand binding^1. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays.It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115^4.;

more info or order :

BioLegend product webpage