Brilliant Violet 711™ anti-mouse CD115 (CSF-1R) | BioLegend 135515 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 711™ anti-mouse CD115 (CSF-1R)

catalog :

135515

quantity :

50 μg

price :

316 USD

clonality :

monoclonal

host :

rat

conjugate :

BV711

clone name :

AFS98

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 5

Reference
Huang X, Ferris S, Kim S, Choudhary M, Belk J, Fan C, et al. Differential usage of transcriptional repressor Zeb2 enhancers distinguishes adult and embryonic hematopoiesis. Immunity. 2021;54:1417-1432.e7 pubmed publisher
Fuster J, Zuriaga M, Zorita V, MacLauchlan S, Polackal M, Viana Huete V, et al. TET2-Loss-of-Function-Driven Clonal Hematopoiesis Exacerbates Experimental Insulin Resistance in Aging and Obesity. Cell Rep. 2020;33:108326 pubmed publisher
Kim S, Bagadia P, Anderson D, Liu T, Huang X, Theisen D, et al. High Amount of Transcription Factor IRF8 Engages AP1-IRF Composite Elements in Enhancers to Direct Type 1 Conventional Dendritic Cell Identity. Immunity. 2020;53:759-774.e9 pubmed publisher
Bagadia P, Huang X, Liu T, Durai V, Grajales Reyes G, Nitschké M, et al. An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development. Nat Immunol. 2019;20:1174-1185 pubmed publisher
Lim J, Park H, Heisler J, Maculins T, Roose Girma M, Xu M, et al. Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins. elife. 2019;8: pubmed publisher

product information

Antigen :

CD115

Apps. Abbrev. :

Flow Cytometry

Cat # :

135515

Clone :

AFS98

Item :

Brilliant Violet 711™ anti-mouse CD115 (CSF-1R)

Isotype :

Rat IgG2a, κ

Other Names :

CSF-1R, M-CSFR, c-fms

Size :

50 μg

Price (USD) :

316 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV711

Application Notes :

Additional reported applications (for the relevant formats) include: blocking of ligand binding 1 . The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays. It has been reported that CD115 can be rapidly internalized, especially when samples are exposed to room temperature. Approximate 33% decrease in CD115 expression has been observed between 0 and 4 hours after sample collection, while overnight incubation of the cells results in complete CD115 downregulation. Pre-treatment with EDTA and low temperatures (2 to 8°C) helps in maintaining surface expression of CD115 4 .

more info or order :

BioLegend product webpage