product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-mouse CD117 (c-kit)
catalog :
135133
quantity :
25 μg
price :
112 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
ACK2
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 2
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2a
Laffey K, Stiles R, Ludescher M, Davis T, Khwaja S, Bram R, et al. Early expression of mature αβ TCR in CD4-CD8- T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations. Proc Natl Acad Sci U S A. 2022;119:e2118529119 pubmed publisher
Pundir P, Liu R, Vasavda C, Serhan N, Limjunyawong N, Yee R, et al. A Connective Tissue Mast-Cell-Specific Receptor Detects Bacterial Quorum-Sensing Molecules and Mediates Antibacterial Immunity. Cell Host Microbe. 2019;26:114-122.e8 pubmed publisher
product information
Antigen :
CD117
Apps. Abbrev. :
FC
Cat # :
135133
Clone :
ACK2
Item :
PerCP/Cyanine5.5 anti-mouse CD117 (c-kit)
Isotype :
Rat IgG2b, κ
Other Names :
c-KIT, Stem Cell Factor Receptor (SCFR)
Size :
25 μg
Price (USD) :
112 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Immunogen :
Murine IL-3 dependent mast cells
Application Notes :
Injection of ACK2 in mice of NOD genetic background is not recommended as mice develop immediate anaphylaxis, resulting in animal death. Treatment is possible with co-injection of Benadryl.^3ACK2 has been reported to block c-Kit function. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 135103). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 135114) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA