PE/Dazzle™ 594 anti-mouse CD117 (c-kit) | BioLegend 135127 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Dazzle™ 594 anti-mouse CD117 (c-kit)

catalog :

135127

quantity :

25 μg

price :

141 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

ACK2

reactivity :

mouse

application :

flow cytometry

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2a	Laffey K, Stiles R, Ludescher M, Davis T, Khwaja S, Bram R, et al. Early expression of mature αβ TCR in CD4-CD8- T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations. Proc Natl Acad Sci U S A. 2022;119:e2118529119 pubmed publisher
	Chiang H, Lu H, Sudhakar J, Chen Y, Shih N, Weng Y, et al. IL-22 initiates an IL-18-dependent epithelial response circuit to enforce intestinal host defence. Nat Commun. 2022;13:874 pubmed publisher
	Chaurio R, Anadon C, Lee Costich T, Payne K, Biswas S, Harro C, et al. TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures. Immunity. 2022;55:115-128.e9 pubmed publisher

product information

Antigen :

CD117

Apps. Abbrev. :

Cat # :

135127

Clone :

ACK2

Item :

PE/Dazzle™ 594 anti-mouse CD117 (c-kit)

Isotype :

Rat IgG2b, κ

Other Names :

c-KIT, Stem Cell Factor Receptor (SCFR)

Size :

25 μg

Price (USD) :

141 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PE_DZL594

Immunogen :

Murine IL-3 dependent mast cells

Application Notes :

Injection of ACK2 in mice of NOD genetic background is not recommended as mice develop immediate anaphylaxis, resulting in animal death. Treatment is possible with co-injection of Benadryl.^3ACK2 has been reported to block c-Kit function. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 135103). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 135114) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;