Brilliant Violet 510™ anti-mouse CD117 (c-kit) | BioLegend 135119 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 510™ anti-mouse CD117 (c-kit)

catalog :

135119

quantity :

125 μL

price :

165 USD

clonality :

monoclonal

host :

rat

conjugate :

BV510

clone name :

ACK2

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig st2	Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, et al. Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016;538:392-396 pubmed publisher
	Zhang J, Muri J, Fitzgerald G, Gorski T, Gianni Barrera R, Masschelein E, et al. Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization. Cell Metab. 2020;31:1136-1153.e7 pubmed publisher
	Bronisz Budzynska I, Chwalenia K, Mucha O, Podkalicka P, Karolina Bukowska Strakova -, Jozkowicz A, et al. miR-146a deficiency does not aggravate muscular dystrophy in mdx mice. Skelet Muscle. 2019;9:22 pubmed publisher

product information

Antigen :

CD117

Apps. Abbrev. :

Cat # :

135119

Clone :

ACK2

Item :

Brilliant Violet 510™ anti-mouse CD117 (c-kit)

Isotype :

Rat IgG2b, κ

Other Names :

c-KIT, Stem Cell Factor Receptor (SCFR)

Size :

125 μL

Price (USD) :

165 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV510

Immunogen :

Murine IL-3 dependent mast cells

Application Notes :

Injection of ACK2 in mice of NOD genetic background is not recommended as mice develop immediate anaphylaxis, resulting in animal death. Treatment is possible with co-injection of Benadryl.^3ACK2 has been reported to block c-Kit function. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 135103). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 135114) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage