Alexa Fluor® 488 anti-mouse CD117 (c-kit) | BioLegend 135118 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 488 anti-mouse CD117 (c-kit)

catalog :

135118

quantity :

100 μg

price :

229 USD

clonality :

monoclonal

host :

rat

conjugate :

AF488

clone name :

ACK2

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 3

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 2a	Laffey K, Stiles R, Ludescher M, Davis T, Khwaja S, Bram R, et al. Early expression of mature αβ TCR in CD4-CD8- T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations. Proc Natl Acad Sci U S A. 2022;119:e2118529119 pubmed publisher
flow cytometry; mouse; 1:100; loading ...; fig s2a	Hyrenius Wittsten A, Pilheden M, Sturesson H, Hansson J, Walsh M, Song G, et al. De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia. Nat Commun. 2018;9:1770 pubmed publisher
	Nyeng P, Heilmann S, Löf Öhlin Z, Pettersson N, Hermann F, Reynolds A, et al. p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019;: pubmed publisher

product information

Antigen :

CD117

Apps. Abbrev. :

Cat # :

135118

Clone :

ACK2

Item :

Alexa Fluor® 488 anti-mouse CD117 (c-kit)

Isotype :

Rat IgG2b, κ

Other Names :

c-KIT, Stem Cell Factor Receptor (SCFR)

Size :

100 μg

Price (USD) :

229 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

A488

Immunogen :

Murine IL-3 dependent mast cells

Application Notes :

Injection of ACK2 in mice of NOD genetic background is not recommended as mice develop immediate anaphylaxis, resulting in animal death. Treatment is possible with co-injection of Benadryl.^3ACK2 has been reported to block c-Kit function. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 135103). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 135114) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage