FITC anti-mouse CD117 (c-kit) | BioLegend 135115 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

FITC anti-mouse CD117 (c-kit)

catalog :

135115

quantity :

50 μg

price :

101 USD

clonality :

monoclonal

host :

rat

conjugate :

FITC

clone name :

ACK2

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 3

Reference
Chen L, Tang S, Zhang F, Garcia V, Falck J, Schwartzman M, et al. CYP4A/20-HETE regulates ischemia-induced neovascularization via its actions on endothelial progenitor and preexisting endothelial cells. Am J Physiol Heart Circ Physiol. 2019;316:H1468-H1479 pubmed publisher
Gubin M, Esaulova E, Ward J, Malkova O, Runci D, Wong P, et al. High-Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling during Successful Immune-Checkpoint Cancer Therapy. Cell. 2018;175:1014-1030.e19 pubmed publisher
Liu X, McBride J, Zhou Y, Liu Z, Ma J. Regulation of endothelial progenitor cell release by Wnt signaling in bone marrow. Invest Ophthalmol Vis Sci. 2013;54:7386-94 pubmed publisher

product information

Antigen :

CD117

Apps. Abbrev. :

Cat # :

135115

Clone :

ACK2

Item :

FITC anti-mouse CD117 (c-kit)

Isotype :

Rat IgG2b, κ

Other Names :

c-KIT, Stem Cell Factor Receptor (SCFR)

Size :

50 μg

Price (USD) :

101 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

FITC

Immunogen :

Murine IL-3 dependent mast cells

Application Notes :

Injection of ACK2 in mice of NOD genetic background is not recommended as mice develop immediate anaphylaxis, resulting in animal death. Treatment is possible with co-injection of Benadryl.^3ACK2 has been reported to block c-Kit function. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 135103). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 135114) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage