product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-mouse CD117 (c-kit)
catalog :
135111
quantity :
25 μg
price :
72 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
ACK2
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 5
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2a
Laffey K, Stiles R, Ludescher M, Davis T, Khwaja S, Bram R, et al. Early expression of mature αβ TCR in CD4-CD8- T cell progenitors enables MHC to drive development of T-ALL bearing NOTCH mutations. Proc Natl Acad Sci U S A. 2022;119:e2118529119 pubmed publisher
Rohner L, Reinhart R, Iype J, Bachmann S, Kaufmann T, Fux M. Impact of BH3-mimetics on Human and Mouse Blood Leukocytes: A Comparative Study. Sci Rep. 2020;10:222 pubmed publisher
Seneviratne A, Xu M, Henao J, Fajardo V, Hao Z, Voisin V, et al. The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids. Cell Stem Cell. 2019;24:621-636.e16 pubmed publisher
Kitadate Y, Jörg D, Tokue M, Maruyama A, Ichikawa R, Tsuchiya S, et al. Competition for Mitogens Regulates Spermatogenic Stem Cell Homeostasis in an Open Niche. Cell Stem Cell. 2019;24:79-92.e6 pubmed publisher
Gong Y, Huang L, Cheng W, Li X, Lu J, Lin L, et al. Roles of interleukin-9 in the growth and cholecystokinin-induced intracellular calcium signaling of cultured interstitial cells of Cajal. PLoS ONE. 2014;9:e95898 pubmed publisher
product information
Antigen :
CD117
Apps. Abbrev. :
FC
Cat # :
135111
Clone :
ACK2
Item :
PE/Cyanine7 anti-mouse CD117 (c-kit)
Isotype :
Rat IgG2b, κ
Other Names :
c-KIT, Stem Cell Factor Receptor (SCFR)
Size :
25 μg
Price (USD) :
72 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
Murine IL-3 dependent mast cells
Application Notes :
Injection of ACK2 in mice of NOD genetic background is not recommended as mice develop immediate anaphylaxis, resulting in animal death. Treatment is possible with co-injection of Benadryl.^3ACK2 has been reported to block c-Kit function. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 135103). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 135114) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA