product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 700 anti-mouse CD41
catalog :
133926
quantity :
100 μg
price :
288 USD
clonality :
monoclonal
host :
rat
conjugate :
AF700
clone name :
MWReg30
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 35
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Lee Y, Kim T, Kim Y, Kim S, Lee S, Seo S, et al. Microbiota-derived lactate promotes hematopoiesis and erythropoiesis by inducing stem cell factor production from leptin receptor+ niche cells. Exp Mol Med. 2021;53:1319-1331 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b, s2
Pariser D, Hilt Z, Ture S, Blick Nitko S, Looney M, Cleary S, et al. Lung megakaryocytes are immune modulatory cells. J Clin Invest. 2021;131: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4d
Ray S, Chee L, Matson D, Palermo N, Bresnick E, Hewitt K. Sterile α-motif domain requirement for cellular signaling and survival. J Biol Chem. 2020;295:7113-7125 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c, 5b
Hayes M, Ward S, Crawford G, Seoane R, Jackson W, Kipling D, et al. Inflammation-induced IgE promotes epithelial hyperplasia and tumour growth. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 1a
Cunin P, Bouslama R, Machlus K, Martínez Bonet M, Lee P, Wactor A, et al. Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 5g
Oda A, Tezuka T, Ueno Y, Hosoda S, Amemiya Y, Notsu C, et al. Niche-induced extramedullary hematopoiesis in the spleen is regulated by the transcription factor Tlx1. Sci Rep. 2018;8:8308 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Mumau M, Vanderbeck A, Lynch E, Golec S, Emerson S, Punt J. Identification of a Multipotent Progenitor Population in the Spleen That Is Regulated by NR4A1. J Immunol. 2018;200:1078-1087 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Harly C, Cam M, Kaye J, Bhandoola A. Development and differentiation of early innate lymphoid progenitors. J Exp Med. 2018;215:249-262 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Patenaude J, Perreault C. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. J Immunol. 2016;196:4760-70 pubmed publisher
  • immunohistochemistry; mouse; 2.5 ug/ml; fig 1
Li Y, Nishikawa T, Kaneda Y. Platelet-cytokine Complex Suppresses Tumour Growth by Exploiting Intratumoural Thrombin-dependent Platelet Aggregation. Sci Rep. 2016;6:25077 pubmed publisher
  • flow cytometry; mouse; fig 1
Cordeiro O, Chypre M, Brouard N, Rauber S, Alloush F, Romera Hernandez M, et al. Integrin-Alpha IIb Identifies Murine Lymph Node Lymphatic Endothelial Cells Responsive to RANKL. PLoS ONE. 2016;11:e0151848 pubmed publisher
  • immunocytochemistry; mouse; fig 8
Nishimura S, Nagasaki M, Kunishima S, Sawaguchi A, Sakata A, Sakaguchi H, et al. IL-1α induces thrombopoiesis through megakaryocyte rupture in response to acute platelet needs. J Cell Biol. 2015;209:453-66 pubmed publisher
  • flow cytometry; mouse; fig 1b
Marks Bluth J, Khanna A, Chandrakanthan V, Thoms J, Bee T, Eich C, et al. SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development. Mol Cell Biol. 2015;35:2165-72 pubmed publisher
McPherson H, Duval C, Baker S, Hindle M, Cheah L, Asquith N, et al. Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability, and resistance to fibrinolysis. elife. 2021;10: pubmed publisher
Chen R, Okeyo Owuor T, Patel R, Casey E, Cluster A, Yang W, et al. Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy. Cell Rep. 2021;34:108751 pubmed publisher
Reimer D, Meyer Hermann M, Rakhymzhan A, Steinmetz T, Tripal P, Thomas J, et al. B Cell Speed and B-FDC Contacts in Germinal Centers Determine Plasma Cell Output via Swiprosin-1/EFhd2. Cell Rep. 2020;32:108030 pubmed publisher
Hudson W, Gensheimer J, Hashimoto M, Wieland A, Valanparambil R, Li P, et al. Proliferating Transitory T Cells with an Effector-like Transcriptional Signature Emerge from PD-1+ Stem-like CD8+ T Cells during Chronic Infection. Immunity. 2019;51:1043-1058.e4 pubmed publisher
Wilkinson A, Ryan D, Kucinski I, Wang W, Yang J, Nestorowa S, et al. Expanded potential stem cell media as a tool to study human developmental hematopoiesis in vitro. Exp Hematol. 2019;76:1-12.e5 pubmed publisher
Pijuan Sala B, Griffiths J, Guibentif C, Hiscock T, Jawaid W, Calero Nieto F, et al. A single-cell molecular map of mouse gastrulation and early organogenesis. Nature. 2019;566:490-495 pubmed publisher
Malara A, Gruppi C, Abbonante V, Cattaneo D, De Marco L, Massa M, et al. EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis. J Exp Med. 2019;216:587-604 pubmed publisher
Comazzetto S, Murphy M, Berto S, Jeffery E, Zhao Z, Morrison S. Restricted Hematopoietic Progenitors and Erythropoiesis Require SCF from Leptin Receptor+ Niche Cells in the Bone Marrow. Cell Stem Cell. 2019;24:477-486.e6 pubmed publisher
Commerford C, Dieterich L, He Y, Hell T, Montoya Zegarra J, Noerrelykke S, et al. Mechanisms of Tumor-Induced Lymphovascular Niche Formation in Draining Lymph Nodes. Cell Rep. 2018;25:3554-3563.e4 pubmed publisher
Upadhaya S, Sawai C, Papalexi E, Rashidfarrokhi A, Jang G, Chattopadhyay P, et al. Kinetics of adult hematopoietic stem cell differentiation in vivo. J Exp Med. 2018;215:2815-2832 pubmed publisher
Plein A, Fantin A, Denti L, Pollard J, Ruhrberg C. Erythro-myeloid progenitors contribute endothelial cells to blood vessels. Nature. 2018;562:223-228 pubmed publisher
Sevin M, Kubovcakova L, Pernet N, Causse S, Vitte F, Villeval J, et al. HSP27 is a partner of JAK2-STAT5 and a potential therapeutic target in myelofibrosis. Nat Commun. 2018;9:1431 pubmed publisher
Han Y, Liu Q, Hou J, Gu Y, Zhang Y, Chen Z, et al. Tumor-Induced Generation of Splenic Erythroblast-like Ter-Cells Promotes Tumor Progression. Cell. 2018;173:634-648.e12 pubmed publisher
Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed publisher
Khoramian Tusi B, Socolovsky M. High-throughput single-cell fate potential assay of murine hematopoietic progenitors in vitro. Exp Hematol. 2018;60:21-29.e3 pubmed publisher
McGarvey A, Rybtsov S, Souilhol C, Tamagno S, Rice R, Hills D, et al. A molecular roadmap of the AGM region reveals BMPER as a novel regulator of HSC maturation. J Exp Med. 2017;214:3731-3751 pubmed publisher
Poulos M, Ramalingam P, Gutkin M, Llanos P, Gilleran K, Rabbany S, et al. Endothelial transplantation rejuvenates aged hematopoietic stem cell function. J Clin Invest. 2017;127:4163-4178 pubmed publisher
Lefrançais E, Ortiz Muñoz G, Caudrillier A, Mallavia B, Liu F, Sayah D, et al. The lung is a site of platelet biogenesis and a reservoir for haematopoietic progenitors. Nature. 2017;544:105-109 pubmed publisher
Malara A, Fresia C, Di Buduo C, Soprano P, Moccia F, Balduini C, et al. The Plant Hormone Abscisic Acid Is a Prosurvival Factor in Human and Murine Megakaryocytes. J Biol Chem. 2017;292:3239-3251 pubmed publisher
Martinod K, Witsch T, Erpenbeck L, Savchenko A, Hayashi H, Cherpokova D, et al. Peptidylarginine deiminase 4 promotes age-related organ fibrosis. J Exp Med. 2017;214:439-458 pubmed publisher
Scialdone A, Tanaka Y, Jawaid W, Moignard V, Wilson N, Macaulay I, et al. Resolving early mesoderm diversification through single-cell expression profiling. Nature. 2016;535:289-293 pubmed publisher
Sullivan B, Wang R, Tawfik O, Luyendyk J. Protective and damaging effects of platelets in acute cholestatic liver injury revealed by depletion and inhibition strategies. Toxicol Sci. 2010;115:286-94 pubmed publisher
product information
Antigen :
CD41
Apps. Abbrev. :
FC
Cat # :
133926
Clone :
MWReg30
Item :
Alexa Fluor® 700 anti-mouse CD41
Isotype :
Rat IgG1, κ
Other Names :
Fibrinogen receptor, gpIIb/IIIa, integrin alpha IIb, CD41a
Size :
100 μg
Price (USD) :
288 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A700
Immunogen :
Mouse platelets
Application Notes :
Additional reported applications (for the relevant formats) include: depletion of platelets and functional assay in vivo.^4,7 The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for in vivo studies (Cat. No. 133939).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA