product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD194 (CCR4)
catalog :
131204
quantity :
100 μg
price :
341 USD
clonality :
monoclonal
host :
hamsters
conjugate :
PE
clone name :
2G12
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 32
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 7b
Tordesillas L, Lozano Ojalvo D, Dunkin D, Mondoulet L, Agudo J, Merad M, et al. PDL2+ CD11b+ dermal dendritic cells capture topical antigen through hair follicles to prime LAP+ Tregs. Nat Commun. 2018;9:5238 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Ushio A, Arakaki R, Otsuka K, Yamada A, Tsunematsu T, Kudo Y, et al. CCL22-Producing Resident Macrophages Enhance T Cell Response in Sjögren's Syndrome. Front Immunol. 2018;9:2594 pubmed publisher
  • flow cytometry; mouse; fig 5d
Keil M, Sonner J, Lanz T, Oezen I, Bunse T, Bittner S, et al. General control non-derepressible 2 (GCN2) in T cells controls disease progression of autoimmune neuroinflammation. J Neuroimmunol. 2016;297:117-26 pubmed publisher
  • flow cytometry; mouse
Peine M, Rausch S, Helmstetter C, Fröhlich A, Hegazy A, Kuhl A, et al. Stable T-bet(+)GATA-3(+) Th1/Th2 hybrid cells arise in vivo, can develop directly from naive precursors, and limit immunopathologic inflammation. PLoS Biol. 2013;11:e1001633 pubmed publisher
Zhang W, Jiang X, ZOU Y, Yuan L, Wang X. Pexidartinib synergize PD-1 antibody through inhibiting treg infiltration by reducing TAM-derived CCL22 in lung adenocarcinoma. Front Pharmacol. 2023;14:1092767 pubmed publisher
Spath S, Roan F, Presnell S, H xf6 llbacher B, Ziegler S. Profiling of Tregs across tissues reveals plasticity in ST2 expression and hierarchies in tissue-specific phenotypes. iScience. 2022;25:104998 pubmed publisher
Lin G, Zhang L, Yan Z, Jiang W, Wu B, Li D, et al. Identification of heterogeneous subsets of aortic interleukin-17A-expressing CD4+ T cells in atherosclerotic mice. Int J Immunopathol Pharmacol. 2022;36:3946320221117933 pubmed publisher
Zhong W, Lin W, Yang Y, Chen D, Cao X, Xu M, et al. An acquired phosphatidylinositol 4-phosphate transport initiates T-cell deterioration and leukemogenesis. Nat Commun. 2022;13:4390 pubmed publisher
Alam A, Levanduski E, Denz P, Villavicencio H, Bhatta M, Alhorebi L, et al. Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer. Cancer Cell. 2022;40:153-167.e11 pubmed publisher
Teng F, Tach xf3 Pi xf1 ot R, Sung B, Farber D, Worgall S, Hammad H, et al. ILC3s control airway inflammation by limiting T cell responses to allergens and microbes. Cell Rep. 2021;37:110051 pubmed publisher
Morimura S, Sugaya M, Oka T, Suga H, Miyagaki T, Tsunemi Y, et al. Increased Regulatory T Cells and Decreased Myeloid-Derived Suppressor Cells Induced by High CCL17 Levels May Account for Normal Incidence of Cancers among Patients with Atopic Dermatitis. Int J Mol Sci. 2021;22: pubmed publisher
Lind L, Svensson A, Thörn K, Krzyzowska M, Eriksson K. CD8+ T cells in the central nervous system of mice with herpes simplex infection are highly activated and express high levels of CCR5 and CXCR3. J Neurovirol. 2021;27:145-153 pubmed publisher
Rashid M, Borin T, Ara R, Piranlioglu R, Achyut B, Korkaya H, et al. Critical immunosuppressive effect of MDSC‑derived exosomes in the tumor microenvironment. Oncol Rep. 2021;45:1171-1181 pubmed publisher
Zhu X, Zhang W, Guo J, Zhang X, Li L, Wang T, et al. Noc4L-Mediated Ribosome Biogenesis Controls Activation of Regulatory and Conventional T Cells. Cell Rep. 2019;27:1205-1220.e4 pubmed publisher
Liu Q, Ma W, Yang J, Zhao Z, Yan K, Yao Y, et al. The CXC Chemokine Receptor 3 Inhibits Autoimmune Cholangitis via CD8+ T Cells but Promotes Colitis via CD4+ T Cells. Front Immunol. 2018;9:1090 pubmed publisher
Matsuo K, Nagakubo D, Komori Y, Fujisato S, Takeda N, Kitamatsu M, et al. CCR4 Is Critically Involved in Skin Allergic Inflammation of BALB/c Mice. J Invest Dermatol. 2018;138:1764-1773 pubmed publisher
Hayatsu N, Miyao T, Tachibana M, Murakami R, Kimura A, Kato T, et al. Analyses of a Mutant Foxp3 Allele Reveal BATF as a Critical Transcription Factor in the Differentiation and Accumulation of Tissue Regulatory T Cells. Immunity. 2017;47:268-283.e9 pubmed publisher
Engel I, Seumois G, Chavez L, Samaniego Castruita D, White B, Chawla A, et al. Innate-like functions of natural killer T cell subsets result from highly divergent gene programs. Nat Immunol. 2016;17:728-39 pubmed publisher
Meadows D, Bahous R, Best A, Rozen R. High Dietary Folate in Mice Alters Immune Response and Reduces Survival after Malarial Infection. PLoS ONE. 2015;10:e0143738 pubmed publisher
Wiesner D, Smith K, Kotov D, Nielsen J, Bohjanen P, Nielsen K. Regulatory T Cell Induction and Retention in the Lungs Drives Suppression of Detrimental Type 2 Th Cells During Pulmonary Cryptococcal Infection. J Immunol. 2016;196:365-74 pubmed publisher
Xia S, Wei J, Wang J, Sun H, Zheng W, Li Y, et al. A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells. J Leukoc Biol. 2014;95:733-742 pubmed
Honjo A, Ogawa H, Azuma M, Tezuka T, Sone S, Biragyn A, et al. Targeted reduction of CCR4⁺ cells is sufficient to suppress allergic airway inflammation. Respir Investig. 2013;51:241-9 pubmed publisher
Suga H, Sugaya M, Miyagaki T, Ohmatsu H, Okochi H, Sato S. CXCR3 deficiency prolongs Th1-type contact hypersensitivity. J Immunol. 2013;190:6059-70 pubmed publisher
Loebbermann J, Durant L, Thornton H, Johansson C, Openshaw P. Defective immunoregulation in RSV vaccine-augmented viral lung disease restored by selective chemoattraction of regulatory T cells. Proc Natl Acad Sci U S A. 2013;110:2987-92 pubmed publisher
Liu Y, Chen K, Wang C, Gong W, Yoshimura T, Liu M, et al. Cell surface receptor FPR2 promotes antitumor host defense by limiting M2 polarization of macrophages. Cancer Res. 2013;73:550-60 pubmed publisher
Ohsugi T, Kumasaka T. Low CD4/CD8 T-cell ratio associated with inflammatory arthropathy in human T-cell leukemia virus type I Tax transgenic mice. PLoS ONE. 2011;6:e18518 pubmed publisher
Lee H, Lee H, Kwon Y, Lee J, Kim J, Shin M, et al. Methyl gallate exhibits potent antitumor activities by inhibiting tumor infiltration of CD4+CD25+ regulatory T cells. J Immunol. 2010;185:6698-705 pubmed publisher
Dogan R, Long N, Forde E, Dennis K, Kohm A, Miller S, et al. CCL22 regulates experimental autoimmune encephalomyelitis by controlling inflammatory macrophage accumulation and effector function. J Leukoc Biol. 2011;89:93-104 pubmed publisher
Moriwaki A, Inoue H, Nakano T, Matsunaga Y, Matsuno Y, Matsumoto T, et al. T cell treatment with small interfering RNA for suppressor of cytokine signaling 3 modulates allergic airway responses in a murine model of asthma. Am J Respir Cell Mol Biol. 2011;44:448-55 pubmed publisher
Sharma R, Deshmukh U, Zheng L, Fu S, Ju S. X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms. J Immunol. 2009;183:3212-8 pubmed publisher
Saito K, Torii M, Ma N, Tsuchiya T, Wang L, Hori T, et al. Differential regulatory function of resting and preactivated allergen-specific CD4+ CD25+ regulatory T cells in Th2-type airway inflammation. J Immunol. 2008;181:6889-97 pubmed
Ueha S, Yoneyama H, Hontsu S, Kurachi M, Kitabatake M, Abe J, et al. CCR7 mediates the migration of Foxp3+ regulatory T cells to the paracortical areas of peripheral lymph nodes through high endothelial venules. J Leukoc Biol. 2007;82:1230-8 pubmed
product information
Antigen :
CD194
Apps. Abbrev. :
FC
Cat # :
131204
Clone :
2G12
Item :
PE anti-mouse CD194 (CCR4)
Isotype :
Armenian Hamster IgG
Other Names :
CC CKR-4, CHEMR1, Cmkbr4, LESTR, MGC151418, Sdf1r
Size :
100 μg
Price (USD) :
341 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
PE
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA