product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse Ly-6C
catalog :
128032
quantity :
500 μL
price :
396 USD
clonality :
monoclonal
host :
rat
conjugate :
BV421
clone name :
HK1.4
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 30
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2c, 2d
Larue M, Parker S, Puccini J, Cammer M, Kimmelman A, Bar Sagi D. Metabolic reprogramming of tumor-associated macrophages by collagen turnover promotes fibrosis in pancreatic cancer. Proc Natl Acad Sci U S A. 2022;119:e2119168119 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1g, s1h, s1i, s5f
Liu M, Wu C, Luo S, Hua Q, Chen H, Weng Y, et al. PERK reprograms hematopoietic progenitor cells to direct tumor-promoting myelopoiesis in the spleen. J Exp Med. 2022;219: pubmed publisher
  • flow cytometry; mouse; fig 1c
Tsao L, Crosby E, Trotter T, Agarwal P, Hwang B, Acharya C, et al. CD47 blockade augmentation of trastuzumab antitumor efficacy dependent on antibody-dependent cellular phagocytosis. JCI Insight. 2019;4: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig e8b
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1d
Kelly A, Günaltay S, McEntee C, Shuttleworth E, Smedley C, Houston S, et al. Human monocytes and macrophages regulate immune tolerance via integrin αvβ8-mediated TGFβ activation. J Exp Med. 2018;215:2725-2736 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4b
Alissafi T, Hatzioannou A, Mintzas K, Barouni R, Banos A, Sormendi S, et al. Autophagy orchestrates the regulatory program of tumor-associated myeloid-derived suppressor cells. J Clin Invest. 2018;128:3840-3852 pubmed publisher
Zheng Y, Chen Z, Zhou B, Chen S, Han L, Chen N, et al. PRMT5 Deficiency Enforces the Transcriptional and Epigenetic Programs of Klrg1+CD8+ Terminal Effector T Cells and Promotes Cancer Development. J Immunol. 2022;208:501-513 pubmed publisher
Rogic A, Pant I, Grumolato L, Fernández Rodríguez R, Edwards A, Das S, et al. High endogenous CCL2 expression promotes the aggressive phenotype of human inflammatory breast cancer. Nat Commun. 2021;12:6889 pubmed publisher
Platt D, Lawrence D, Rodgers R, Schriefer L, Qian W, Miner C, et al. Transferrable protection by gut microbes against STING-associated lung disease. Cell Rep. 2021;35:109113 pubmed publisher
Jassinskaja M, Pimková K, Arh N, Johansson E, Davoudi M, Pereira C, et al. Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells. Cell Rep. 2021;34:108894 pubmed publisher
Nahrendorf W, Ivens A, Spence P. Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria. elife. 2021;10: pubmed publisher
Wang J, Xu Y, Chen Z, Liang J, Lin Z, Liang H, et al. Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia. Cell. 2020;183:1867-1883.e26 pubmed publisher
Kalafati L, Kourtzelis I, Schulte Schrepping J, Li X, Hatzioannou A, Grinenko T, et al. Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity. Cell. 2020;183:771-785.e12 pubmed publisher
Barberio A, Smith S, Correa S, Nguyen C, Nhan B, Melo M, et al. Cancer Cell Coating Nanoparticles for Optimal Tumor-Specific Cytokine Delivery. ACS Nano. 2020;14:11238-11253 pubmed publisher
Lian J, Ozga A, Sokol C, Luster A. Targeting Lymph Node Niches Enhances Type 1 Immune Responses to Immunization. Cell Rep. 2020;31:107679 pubmed publisher
Riquelme S, Liimatta K, Wong Fok Lung T, Fields B, Ahn D, Chen D, et al. Pseudomonas aeruginosa Utilizes Host-Derived Itaconate to Redirect Its Metabolism to Promote Biofilm Formation. Cell Metab. 2020;31:1091-1106.e6 pubmed publisher
Park C, Lin P, Zhou S, Barakat R, Bashir S, Choi J, et al. Progesterone Receptor Serves the Ovary as a Trigger of Ovulation and a Terminator of Inflammation. Cell Rep. 2020;31:107496 pubmed publisher
Buffolo M, Pires K, Ferhat M, Ilkun O, Makaju A, Achenbach A, et al. Identification of a Paracrine Signaling Mechanism Linking CD34high Progenitors to the Regulation of Visceral Fat Expansion and Remodeling. Cell Rep. 2019;29:270-282.e5 pubmed publisher
Harel M, Ortenberg R, Varanasi S, Mangalhara K, Mardamshina M, Markovits E, et al. Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. Cell. 2019;179:236-250.e18 pubmed publisher
Calvente C, Tameda M, Johnson C, Del Pilar H, Lin Y, Adronikou N, et al. Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223. J Clin Invest. 2019;129:4091-4109 pubmed publisher
Casulli J, Fife M, Houston S, Rossi S, Dow J, Williamson E, et al. CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality. Nat Commun. 2019;10:2121 pubmed publisher
Yoshida H, Lareau C, Ramirez R, Rose S, Maier B, Wroblewska A, et al. The cis-Regulatory Atlas of the Mouse Immune System. Cell. 2019;176:897-912.e20 pubmed publisher
Hepler C, Shan B, Zhang Q, Henry G, Shao M, Vishvanath L, et al. Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice. elife. 2018;7: pubmed publisher
Bennett F, Bennett M, Yaqoob F, Mulinyawe S, Grant G, Hayden Gephart M, et al. A Combination of Ontogeny and CNS Environment Establishes Microglial Identity. Neuron. 2018;98:1170-1183.e8 pubmed publisher
Guichard V, Bonilla N, Durand A, Audemard Verger A, Guilbert T, Martin B, et al. Calcium-mediated shaping of naive CD4 T-cell phenotype and function. elife. 2017;6: pubmed publisher
Martins R, Maier J, Gorki A, Huber K, Sharif O, Starkl P, et al. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nat Immunol. 2016;17:1361-1372 pubmed publisher
Zhang Q, Hu X, Liu Y, Ye Z, Gui Y, Zhou D, et al. CD11b deficiency suppresses intestinal tumor growth by reducing myeloid cell recruitment. Sci Rep. 2015;5:15948 pubmed publisher
Levy N, Milikovsky D, Baranauskas G, Vinogradov E, David Y, Ketzef M, et al. Differential TGF-β Signaling in Glial Subsets Underlies IL-6-Mediated Epileptogenesis in Mice. J Immunol. 2015;195:1713-22 pubmed publisher
Watson N, Schneider K, Massa P. SHP-1-dependent macrophage differentiation exacerbates virus-induced myositis. J Immunol. 2015;194:2796-809 pubmed publisher
Zuber J, Radtke I, Pardee T, Zhao Z, Rappaport A, Luo W, et al. Mouse models of human AML accurately predict chemotherapy response. Genes Dev. 2009;23:877-89 pubmed publisher
product information
Antigen :
Ly-6C
Apps. Abbrev. :
FC
Cat # :
128032
Clone :
HK1.4
Item :
Brilliant Violet 421™ anti-mouse Ly-6C
Isotype :
Rat IgG2c, κ
Other Names :
Lymphocyte antigen 6 complex, locus C
Size :
500 μL
Price (USD) :
396 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BV421
Immunogen :
L3 cloned CTL cells
Application Notes :
Clone HK1.4 does not block the binding of clone RB6-8C5^8.Additional reported applications (for relevant formats of this clone) include: in vitro activation of T cells^1-3 and immunohistochemistry of frozen sections^4.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA