product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse TCR Vα2
catalog :
127802
quantity :
250 μg
price :
206 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
B20.1
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section, mass cytometry
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • mass cytometry; mouse; loading ...
Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...
Fernandes R, Li C, Wang G, Yang X, Savvides C, Glassman C, et al. Discovery of surrogate agonists for visceral fat Treg cells that modulate metabolic indices in vivo. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Khanom U, Ohigashi I, Fujimori S, Kondo K, Takada K, Takahama Y. TCR Affinity for In Vivo Peptide-Induced Thymic Positive Selection Fine-Tunes TCR Responsiveness of Peripheral CD8+ T Cells. J Immunol. 2019;: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s3i
Macdougall C, Wood E, Loschko J, Scagliotti V, Cassidy F, Robinson M, et al. Visceral Adipose Tissue Immune Homeostasis Is Regulated by the Crosstalk between Adipocytes and Dendritic Cell Subsets. Cell Metab. 2018;27:588-601.e4 pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 4a
Siracusa F, McGrath M, Maschmeyer P, Bardua M, Lehmann K, Heinz G, et al. Nonfollicular reactivation of bone marrow resident memory CD4 T cells in immune clusters of the bone marrow. Proc Natl Acad Sci U S A. 2018;115:1334-1339 pubmed publisher
  • flow cytometry; mouse; fig 1b
Lehmann C, Baranska A, Heidkamp G, Heger L, Neubert K, Lühr J, et al. DC subset-specific induction of T cell responses upon antigen uptake via Fc? receptors in vivo. J Exp Med. 2017;214:1509-1528 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5b
Kretzer N, Theisen D, Tussiwand R, Briseño C, Grajales Reyes G, Wu X, et al. RAB43 facilitates cross-presentation of cell-associated antigens by CD8?+ dendritic cells. J Exp Med. 2016;213:2871-2883 pubmed
  • flow cytometry; mouse; loading ...; fig s1
Sen D, Kaminski J, Barnitz R, Kurachi M, Gerdemann U, Yates K, et al. The epigenetic landscape of T cell exhaustion. Science. 2016;354:1165-1169 pubmed
  • flow cytometry; mouse
Pizzolla A, Oh D, Luong S, Prickett S, Henstridge D, Febbraio M, et al. High Fat Diet Inhibits Dendritic Cell and T Cell Response to Allergens but Does Not Impair Inhalational Respiratory Tolerance. PLoS ONE. 2016;11:e0160407 pubmed publisher
  • flow cytometry; mouse; 10 ug/ml
Sasaki K, Takada K, Ohte Y, Kondo H, Sorimachi H, Tanaka K, et al. Thymoproteasomes produce unique peptide motifs for positive selection of CD8(+) T cells. Nat Commun. 2015;6:7484 pubmed publisher
  • flow cytometry; mouse; fig s12
Yang S, Fujikado N, Kolodin D, Benoist C, Mathis D. Immune tolerance. Regulatory T cells generated early in life play a distinct role in maintaining self-tolerance. Science. 2015;348:589-94 pubmed publisher
  • flow cytometry; mouse
Iwata A, Kawashima S, Kobayashi M, Okubo A, Kawashima H, Suto A, et al. Th2-type inflammation instructs inflammatory dendritic cells to induce airway hyperreactivity. Int Immunol. 2014;26:103-14 pubmed publisher
Paterson M, Caldera J, Nguyen C, Sharma P, Castro A, Kolar S, et al. Harnessing antifungal immunity in pursuit of a Staphylococcus aureus vaccine strategy. PLoS Pathog. 2020;16:e1008733 pubmed publisher
Yang J, Wang H, Xie J, Li L, Wang J, Wan E, et al. DGK α and ζ Activities Control TH1 and TH17 Cell Differentiation. Front Immunol. 2019;10:3048 pubmed publisher
Sakamoto S, Kagawa S, Kuwada K, Ito A, Kajioka H, Kakiuchi Y, et al. Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer. Oncoimmunology. 2019;8:e1671760 pubmed publisher
Guo R, Hu F, Weng Q, Lv C, Wu H, Liu L, et al. Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors. Cell Res. 2020;30:21-33 pubmed publisher
Saraiva D, Jacinto A, Borralho P, Braga S, Cabral M. HLA-DR in Cytotoxic T Lymphocytes Predicts Breast Cancer Patients' Response to Neoadjuvant Chemotherapy. Front Immunol. 2018;9:2605 pubmed publisher
Kakaradov B, Arsenio J, Widjaja C, He Z, Aigner S, Metz P, et al. Early transcriptional and epigenetic regulation of CD8+ T cell differentiation revealed by single-cell RNA sequencing. Nat Immunol. 2017;18:422-432 pubmed publisher
Rao R, Li Q, Gubbels Bupp M, Shrikant P. Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation. Immunity. 2012;36:374-87 pubmed publisher
Steptoe R, Ritchie J, Wilson N, Villadangos J, Lew A, Harrison L. Cognate CD4+ help elicited by resting dendritic cells does not impair the induction of peripheral tolerance in CD8+ T cells. J Immunol. 2007;178:2094-103 pubmed
Kao C, Daniels M, Jameson S. Loss of CD8 and TCR binding to Class I MHC ligands following T cell activation. Int Immunol. 2005;17:1607-17 pubmed
product information
Antigen :
TCR Valpha2
Apps. Abbrev. :
FC
Cat # :
127802
Clone :
B20.1
Item :
Purified anti-mouse TCR Vα2
Isotype :
Rat IgG2a, λ
Other Names :
T cell receptor Vα 2
Size :
250 μg
Price (USD) :
206 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
Soluble TCR from mouse CTL clone KB5-C20
Application Notes :
The B20.1 antibody recognizes most members of the Va2 TCR subfamily in mice having the a, b, and c haplotypes.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA