product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Ultra-LEAF™ Purified anti-mouse Ly-6G
catalog :
127680
quantity :
100 μg
price :
110 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
1A8
reactivity :
mouse
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig s2
Aiken T, Erbe A, Zebertavage L, Komjathy D, Feils A, Rodriguez M, et al. Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma. J Immunother Cancer. 2022;10: pubmed publisher
Banka A, Guevara M, Brannon E, Nguyen N, Song S, Cady G, et al. Cargo-free particles divert neutrophil-platelet aggregates to reduce thromboinflammation. Nat Commun. 2023;14:2462 pubmed publisher
Haffner Luntzer M, Weber B, Morioka K, Lackner I, Fischer V, Bahney C, et al. Altered early immune response after fracture and traumatic brain injury. Front Immunol. 2023;14:1074207 pubmed publisher
Pernet E, Sun S, Sarden N, Gona S, Nguyen A, Khan N, et al. Neonatal imprinting of alveolar macrophages via neutrophil-derived 12-HETE. Nature. 2023;614:530-538 pubmed publisher
Li Y, Xu J, Yu T, Zhu J, Xuan A, Liu X, et al. A labeling strategy for the three-dimensional recognition and analysis of microvascular obstruction in ischemic stroke. Theranostics. 2023;13:403-416 pubmed publisher
Kuhn M, Haffner Luntzer M, Kempter E, Reber S, Ichinose H, Vacher J, et al. Myeloid cell-derived catecholamines influence bone turnover and regeneration in mice. Front Endocrinol (Lausanne). 2022;13:997745 pubmed publisher
Gawish R, Maier B, Obermayer G, Watzenboeck M, Gorki A, Quattrone F, et al. A neutrophil-B-cell axis impacts tissue damage control in a mouse model of intraabdominal bacterial infection via Cxcr4. elife. 2022;11: pubmed publisher
Hu J, Ji Q, Chen F, Gong X, Chen C, Zhang K, et al. CXCR2 Is Essential for Radiation-Induced Intestinal Injury by Initiating Neutrophil Infiltration. J Immunol Res. 2022;2022:7966089 pubmed publisher
Fischer V, Ragipoglu D, Diedrich J, Steppe L, Dudeck A, Sch xfc tze K, et al. Mast Cells Trigger Disturbed Bone Healing in Osteoporotic Mice. J Bone Miner Res. 2022;37:137-151 pubmed publisher
Kim A, Kim S, Leszczyńska A, Kaufmann B, Reca A, Kim D, et al. Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis. Sci Rep. 2021;11:24194 pubmed publisher
Zheng Z, Li Y, Jia S, Zhu M, Cao L, Tao M, et al. Lung mesenchymal stromal cells influenced by Th2 cytokines mobilize neutrophils and facilitate metastasis by producing complement C3. Nat Commun. 2021;12:6202 pubmed publisher
Kaiser R, Leunig A, Pekayvaz K, Popp O, Joppich M, Polewka V, et al. Self-sustaining IL-8 loops drive a prothrombotic neutrophil phenotype in severe COVID-19. JCI Insight. 2021;6: pubmed publisher
Deng H, Kan A, Lyu N, He M, Huang X, Qiao S, et al. Tumor-derived lactate inhibit the efficacy of lenvatinib through regulating PD-L1 expression on neutrophil in hepatocellular carcinoma. J Immunother Cancer. 2021;9: pubmed publisher
Pan Y, Nishikawa T, Chang C, Tai J, Kaneda Y. CXCL2 combined with HVJ-E suppresses tumor growth and lung metastasis in breast cancer and enhances anti-PD-1 antibody therapy. Mol Ther Oncolytics. 2021;20:175-186 pubmed publisher
Chen J, Zhu Z, Li Q, Lin Y, Dang E, Meng H, et al. Neutrophils Enhance Cutaneous Vascular Dilation and Permeability to Aggravate Psoriasis by Releasing Matrix Metallopeptidase 9. J Invest Dermatol. 2021;141:787-799 pubmed publisher
Shang Q, Chu Y, Li Y, Han Y, Yu D, Liu R, et al. Adipose-derived mesenchymal stromal cells promote corneal wound healing by accelerating the clearance of neutrophils in cornea. Cell Death Dis. 2020;11:707 pubmed publisher
Calvente C, Tameda M, Johnson C, Del Pilar H, Lin Y, Adronikou N, et al. Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223. J Clin Invest. 2019;129:4091-4109 pubmed publisher
Haffner Luntzer M, Foertsch S, Fischer V, Prystaz K, Tschaffon M, Mödinger Y, et al. Chronic psychosocial stress compromises the immune response and endochondral ossification during bone fracture healing via β-AR signaling. Proc Natl Acad Sci U S A. 2019;116:8615-8622 pubmed publisher
Liu Y, Teng Y, Cheng P, Kong H, Lv Y, Mao F, et al. Abrogation of cathepsin C by Helicobacter pylori impairs neutrophil activation to promote gastric infection. FASEB J. 2019;33:5018-5033 pubmed publisher
Mödinger Y, Rapp A, Vikman A, Ren Z, Fischer V, Bergdolt S, et al. Reduced Terminal Complement Complex Formation in Mice Manifests in Low Bone Mass and Impaired Fracture Healing. Am J Pathol. 2019;189:147-161 pubmed publisher
Wang T, Fan C, Yao A, Xu X, Zheng G, You Y, et al. The Adaptor Protein CARD9 Protects against Colon Cancer by Restricting Mycobiota-Mediated Expansion of Myeloid-Derived Suppressor Cells. Immunity. 2018;49:504-514.e4 pubmed publisher
Kaiser K, Prystaz K, Vikman A, Haffner Luntzer M, Bergdolt S, Strauss G, et al. Pharmacological inhibition of IL-6 trans-signaling improves compromised fracture healing after severe trauma. Naunyn Schmiedebergs Arch Pharmacol. 2018;391:523-536 pubmed publisher
Prystaz K, Kaiser K, Kovtun A, Haffner Luntzer M, Fischer V, Rapp A, et al. Distinct Effects of IL-6 Classic and Trans-Signaling in Bone Fracture Healing. Am J Pathol. 2018;188:474-490 pubmed publisher
Bergdolt S, Kovtun A, Hägele Y, Liedert A, Schinke T, Amling M, et al. Osteoblast-specific overexpression of complement receptor C5aR1 impairs fracture healing. PLoS ONE. 2017;12:e0179512 pubmed publisher
Kemmler J, Bindl R, McCook O, Wagner F, Gröger M, Wagner K, et al. Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma. PLoS ONE. 2015;10:e0131194 pubmed publisher
product information
Antigen :
Ly-6G
Apps. Abbrev. :
FC, Depletion, IHC
Cat # :
127680
Clone :
1A8
Item :
Ultra-LEAF™ Purified anti-mouse Ly-6G
Isotype :
Rat IgG2a, κ
Other Names :
Lymphocyte antigen 6 complex, locus G
Size :
100 μg
Price (USD) :
110 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
ULEAF
Immunogen :
Ly-6G transfected EL-4J cell line.
Application Notes :
While 1A8 recognizes only Ly-6G, clone RB6-8C5 recognizes both Ly-6G and Ly-6C. Clone RB6-8C5 binds with high affinity to mouse Ly-6G molecules and to a lower extent to Ly-6C^15. Clone RB6-8C5 impairs the binding of anti-mouse Ly-6G clone 1A8^15. However, clone RB6-8C5 is able to stain in the presence of anti-mouse Ly-6C clone HK1.4^16.Additional reported applications (for the relevant formats) include: immunohistochemistry^9 of frozen sections^10 and paraffin-embedded sections^11, depletion^4, 12-14, and spatial biology (IBEX)^20,21. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for in vivo studies or highly sensitive assays (Cat. No. 127632, 127649, 127650, 127661 and 127662).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA