product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-mouse Ly-6G
catalog :
127618
quantity :
100 μg
price :
303 USD
clonality :
monoclonal
host :
rat
conjugate :
PE/Cy7
clone name :
1A8
reactivity :
human, mouse
application :
flow cytometry
more info or order :
citations: 115
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...
Smith K, Minns D, McHugh B, Holloway R, O CONNOR R, Williams A, et al. The antimicrobial peptide cathelicidin drives development of experimental autoimmune encephalomyelitis in mice by affecting Th17 differentiation. PLoS Biol. 2022;20:e3001554 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1e
Ngamsri K, Putri R, Jans C, Schindler K, Fuhr A, Zhang Y, et al. CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling. Int J Mol Sci. 2021;22: pubmed publisher
  • flow cytometry; human; fig s3a
Fahy N, Palomares Cabeza V, Lolli A, Witte Bouma J, Merino A, Ridwan Y, et al. Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model. Front Immunol. 2021;12:715267 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5b
Snyder L, Doherty C, Mercer H, Denkers E. Induction of IL-12p40 and type 1 immunity by Toxoplasma gondii in the absence of the TLR-MyD88 signaling cascade. PLoS Pathog. 2021;17:e1009970 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3i
Yan C, Saleh N, Yang J, Nebhan C, Vilgelm A, Reddy E, et al. Novel induction of CD40 expression by tumor cells with RAS/RAF/PI3K pathway inhibition augments response to checkpoint blockade. Mol Cancer. 2021;20:85 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 5d
Liu K, Jing N, Wang D, Xu P, Wang J, Chen X, et al. A novel mouse model for liver metastasis of prostate cancer reveals dynamic tumour-immune cell communication. Cell Prolif. 2021;54:e13056 pubmed publisher
  • flow cytometry; mouse; loading ...
Ngamsri K, Gamper Tsigaras J, Reutershan J, Konrad F. Fractalkine Is Linked to the Necrosome Pathway in Acute Pulmonary Inflammation. Front Med (Lausanne). 2021;8:591790 pubmed publisher
  • flow cytometry; mouse; 1:800; loading ...; fig 2d, 3s3c
Burfeind K, Zhu X, Norgard M, Levasseur P, Huisman C, Buenafe A, et al. Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1g
Zhou Y, Lei J, Xie Q, Wu L, Jin S, Guo B, et al. Fibrinogen-like protein 2 controls sepsis catabasis by interacting with resolvin Dp5. Sci Adv. 2019;5:eaax0629 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 7h
Liu D, Yin X, Olyha S, Nascimento M, Chen P, White T, et al. IL-10-Dependent Crosstalk between Murine Marginal Zone B Cells, Macrophages, and CD8α+ Dendritic Cells Promotes Listeria monocytogenes Infection. Immunity. 2019;: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 4b
Kuriakose J, Redecke V, Guy C, Zhou J, Wu R, Ippagunta S, et al. Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis. J Clin Invest. 2019;129:2251-2265 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3b
Mogilenko D, Haas J, L homme L, Fleury S, Quemener S, Levavasseur M, et al. Metabolic and Innate Immune Cues Merge into a Specific Inflammatory Response via the UPR. Cell. 2019;177:1201-1216.e19 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 5h, 5i
Campana L, Starkey Lewis P, Pellicoro A, Aucott R, Man J, O Duibhir E, et al. The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury. J Immunol. 2018;200:1169-1187 pubmed publisher
  • flow cytometry; mouse; fig 8
Liechtenstein T, Perez Janices N, Blanco Luquin I, Goyvaerts C, Schwarze J, Dufait I, et al. Anti-melanoma vaccines engineered to simultaneously modulate cytokine priming and silence PD-L1 characterized using ex vivo myeloid-derived suppressor cells as a readout of therapeutic efficacy. Oncoimmunology. 2014;3:e945378 pubmed
Tang S, Shi L, Luker B, Mickler C, Suresh B, Lesinski G, et al. Modulation of the tumor microenvironment by armed vesicular stomatitis virus in a syngeneic pancreatic cancer model. Virol J. 2022;19:32 pubmed publisher
Yang Y, Wu J, Li Q, Wang J, Mu L, Hui L, et al. A non-bactericidal cathelicidin provides prophylactic efficacy against bacterial infection by driving phagocyte influx. elife. 2022;11: pubmed publisher
Yu X, Bai Y, Han B, Ju M, Tang T, Shen L, et al. Extracellular vesicle-mediated delivery of circDYM alleviates CUS-induced depressive-like behaviours. J Extracell Vesicles. 2022;11:e12185 pubmed publisher
Uddin M, Leslie J, Burgess S, Oakland N, Thompson B, Abhyankar M, et al. The IL-33-ILC2 pathway protects from amebic colitis. Mucosal Immunol. 2022;15:165-175 pubmed publisher
Guo L, Li N, Yang Z, Li H, Zheng H, Yang J, et al. Role of CXCL5 in Regulating Chemotaxis of Innate and Adaptive Leukocytes in Infected Lungs Upon Pulmonary Influenza Infection. Front Immunol. 2021;12:785457 pubmed publisher
Xiao Y, Lidsky P, Shirogane Y, Aviner R, Wu C, Li W, et al. A defective viral genome strategy elicits broad protective immunity against respiratory viruses. Cell. 2021;184:6037-6051.e14 pubmed publisher
Stump C, Roehle K, Manjarrez Orduno N, Dougan S. Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer. Open Biol. 2021;11:210245 pubmed publisher
Tang W, He J, Huang T, Bai Z, Wang C, Wang H, et al. Hlf Expression Marks Early Emergence of Hematopoietic Stem Cell Precursors With Adult Repopulating Potential and Fate. Front Cell Dev Biol. 2021;9:728057 pubmed publisher
Jütte B, Krollmann C, Cieslak K, Koerber R, Boor P, Graef C, et al. Intercellular cGAMP transmission induces innate immune activation and tissue inflammation in Trex1 deficiency. iScience. 2021;24:102833 pubmed publisher
Murdock B, Famie J, Piecuch C, Raue K, Mendelson F, Pieroni C, et al. NK cells associate with ALS in a sex- and age-dependent manner. JCI Insight. 2021;6: pubmed publisher
Zhu B, Wu Y, Huang S, Zhang R, Son Y, Li C, et al. Uncoupling of macrophage inflammation from self-renewal modulates host recovery from respiratory viral infection. Immunity. 2021;54:1200-1218.e9 pubmed publisher
Uzhachenko R, Bharti V, Ouyang Z, Blevins A, Mont S, Saleh N, et al. Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors. Cell Rep. 2021;35:108944 pubmed publisher
Jassinskaja M, Pimková K, Arh N, Johansson E, Davoudi M, Pereira C, et al. Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells. Cell Rep. 2021;34:108894 pubmed publisher
Singh S, Thompson J, Yilmaz B, Li H, Weis S, Sobral D, et al. Loss of α-gal during primate evolution enhanced antibody-effector function and resistance to bacterial sepsis. Cell Host Microbe. 2021;29:347-361.e12 pubmed publisher
Kwak T, Wang F, Deng H, Condamine T, Kumar V, Perego M, et al. Distinct Populations of Immune-Suppressive Macrophages Differentiate from Monocytic Myeloid-Derived Suppressor Cells in Cancer. Cell Rep. 2020;33:108571 pubmed publisher
Engler A, Ysasi A, Pihl R, Villacorta Martin C, Heston H, Richardson H, et al. Airway-Associated Macrophages in Homeostasis and Repair. Cell Rep. 2020;33:108553 pubmed publisher
Argüello R, Combes A, Char R, Gigan J, Baaziz A, Bousiquot E, et al. SCENITH: A Flow Cytometry-Based Method to Functionally Profile Energy Metabolism with Single-Cell Resolution. Cell Metab. 2020;32:1063-1075.e7 pubmed publisher
Lu S, Jolly A, Strand K, Dubner A, Mutryn M, Moulton K, et al. Smooth muscle-derived progenitor cell myofibroblast differentiation through KLF4 downregulation promotes arterial remodeling and fibrosis. JCI Insight. 2020;5: pubmed publisher
Donlan A, Simpson M, Petri W. Type 2 cytokines IL-4 and IL-5 reduce severe outcomes from Clostridiodes difficile infection. Anaerobe. 2020;66:102275 pubmed publisher
Pfirschke C, Engblom C, Gungabeesoon J, Lin Y, Rickelt S, Zilionis R, et al. Tumor-Promoting Ly-6G+ SiglecFhigh Cells Are Mature and Long-Lived Neutrophils. Cell Rep. 2020;32:108164 pubmed publisher
Starkl P, Watzenboeck M, Popov L, Zahalka S, Hladik A, Lakovits K, et al. IgE Effector Mechanisms, in Concert with Mast Cells, Contribute to Acquired Host Defense against Staphylococcusaureus. Immunity. 2020;53:793-804.e9 pubmed publisher
Lin R, Zhang Y, Pradhan K, Li L. TICAM2-related pathway mediates neutrophil exhaustion. Sci Rep. 2020;10:14397 pubmed publisher
Liu X, Boyer M, Holmgren A, Shin S. Legionella-Infected Macrophages Engage the Alveolar Epithelium to Metabolically Reprogram Myeloid Cells and Promote Antibacterial Inflammation. Cell Host Microbe. 2020;28:683-698.e6 pubmed publisher
Israelow B, Song E, Mao T, Lu P, Meir A, Liu F, et al. Mouse model of SARS-CoV-2 reveals inflammatory role of type I interferon signaling. J Exp Med. 2020;217: pubmed publisher
Kwok I, Becht E, Xia Y, Ng M, Teh Y, Tan L, et al. Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor. Immunity. 2020;: pubmed publisher
Soni C, Perez O, Voss W, Pucella J, Serpas L, Mehl J, et al. Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA. Immunity. 2020;52:1022-1038.e7 pubmed publisher
Davidson S, Efremova M, Riedel A, Mahata B, Pramanik J, Huuhtanen J, et al. Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth. Cell Rep. 2020;31:107628 pubmed publisher
Mercer H, Snyder L, Doherty C, Fox B, Bzik D, Denkers E. Toxoplasma gondii dense granule protein GRA24 drives MyD88-independent p38 MAPK activation, IL-12 production and induction of protective immunity. PLoS Pathog. 2020;16:e1008572 pubmed publisher
Nguyen G, Shaban L, Mack M, Swanson K, Bunnell S, Sykes D, et al. SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst. elife. 2020;9: pubmed publisher
Sitnik S, Masemann D, Leite Dantas R, Wixler V, Ludwig S. PD-1 IC Inhibition Synergistically Improves Influenza A Virus-Mediated Oncolysis of Metastatic Pulmonary Melanoma. Mol Ther Oncolytics. 2020;17:190-204 pubmed publisher
Hewitson J, West K, James K, Rani G, Dey N, Romano A, et al. Malat1 Suppresses Immunity to Infection through Promoting Expression of Maf and IL-10 in Th Cells. J Immunol. 2020;204:2949-2960 pubmed publisher
Shook B, Wasko R, Mano O, Rutenberg Schoenberg M, Rudolph M, Zirak B, et al. Dermal Adipocyte Lipolysis and Myofibroblast Conversion Are Required for Efficient Skin Repair. Cell Stem Cell. 2020;26:880-895.e6 pubmed publisher
Ngamsri K, Jans C, Putri R, Schindler K, Gamper Tsigaras J, Eggstein C, et al. Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation. Front Immunol. 2020;11:407 pubmed publisher
Han P, Hanlon D, Arshad N, Lee J, Tatsuno K, Robinson E, et al. Platelet P-selectin initiates cross-presentation and dendritic cell differentiation in blood monocytes. Sci Adv. 2020;6:eaaz1580 pubmed publisher
Brown C, Gudjonson H, Pritykin Y, Deep D, Lavallée V, Mendoza A, et al. Transcriptional Basis of Mouse and Human Dendritic Cell Heterogeneity. Cell. 2019;179:846-863.e24 pubmed publisher
Yadava K, Medina C, Ishak H, Gurevich I, Kuipers H, Shamskhou E, et al. Natural Tr1-like cells do not confer long-term tolerogenic memory. elife. 2019;8: pubmed publisher
Jordan S, Tung N, Casanova Acebes M, Chang C, Cantoni C, Zhang D, et al. Dietary Intake Regulates the Circulating Inflammatory Monocyte Pool. Cell. 2019;178:1102-1114.e17 pubmed publisher
Kim T, Park G, Kim J, Lim S, Kim J, Im K, et al. CD160 serves as a negative regulator of NKT cells in acute hepatic injury. Nat Commun. 2019;10:3258 pubmed publisher
Swidergall M, Solis N, Wang Z, Phan Q, Marshall M, Lionakis M, et al. EphA2 Is a Neutrophil Receptor for Candida albicans that Stimulates Antifungal Activity during Oropharyngeal Infection. Cell Rep. 2019;28:423-433.e5 pubmed publisher
Frisbee A, Saleh M, Young M, Leslie J, Simpson M, Abhyankar M, et al. IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection. Nat Commun. 2019;10:2712 pubmed publisher
Li Y, Zou W, Brestoff J, Rohatgi N, Wu X, Atkinson J, et al. Fat-Produced Adipsin Regulates Inflammatory Arthritis. Cell Rep. 2019;27:2809-2816.e3 pubmed publisher
Saleh M, Frisbee A, Leslie J, Buonomo E, Cowardin C, Ma J, et al. Colitis-Induced Th17 Cells Increase the Risk for Severe Subsequent Clostridium difficile Infection. Cell Host Microbe. 2019;25:756-765.e5 pubmed publisher
Burzynski L, Humphry M, Pyrillou K, Wiggins K, Chan J, Figg N, et al. The Coagulation and Immune Systems Are Directly Linked through the Activation of Interleukin-1α by Thrombin. Immunity. 2019;50:1033-1042.e6 pubmed publisher
Zhao J, Wen X, Tian L, Li T, Xu C, Wen X, et al. Irreversible electroporation reverses resistance to immune checkpoint blockade in pancreatic cancer. Nat Commun. 2019;10:899 pubmed publisher
Geng S, Zhang Y, Lee C, Li L. Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis. Sci Adv. 2019;5:eaav2309 pubmed publisher
Fischer K, Yajjala V, Bansal S, Bauer C, Chen R, Sun K. Monocytes Represent One Source of Bacterial Shielding from Antibiotics following Influenza Virus Infection. J Immunol. 2019;202:2027-2034 pubmed publisher
Domingos Pereira S, Sathiyanadan K, La Rosa S, Polák L, Chevalier M, Martel P, et al. Intravesical Ty21a Vaccine Promotes Dendritic Cells and T Cell-Mediated Tumor Regression in the MB49 Bladder Cancer Model. Cancer Immunol Res. 2019;: pubmed publisher
Dmitrieva Posocco O, Dzutsev A, Posocco D, Hou V, Yuan W, Thovarai V, et al. Cell-Type-Specific Responses to Interleukin-1 Control Microbial Invasion and Tumor-Elicited Inflammation in Colorectal Cancer. Immunity. 2019;50:166-180.e7 pubmed publisher
Zhou J, Xu J, Zhang L, Liu S, Ma Y, Wen X, et al. Combined Single-Cell Profiling of lncRNAs and Functional Screening Reveals that H19 Is Pivotal for Embryonic Hematopoietic Stem Cell Development. Cell Stem Cell. 2019;24:285-298.e5 pubmed publisher
Cheng Y, Tang X, Li Y, Zhao D, Cao Q, Wu H, et al. Depression-Induced Neuropeptide Y Secretion Promotes Prostate Cancer Growth by Recruiting Myeloid Cells. Clin Cancer Res. 2019;25:2621-2632 pubmed publisher
Braza M, van Leent M, Lameijer M, Sanchez Gaytan B, Arts R, Pérez Medina C, et al. Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance. Immunity. 2018;49:819-828.e6 pubmed publisher
Buxade M, Huerga Encabo H, Riera Borrull M, Quintana Gallardo L, López Cotarelo P, Tellechea M, et al. Macrophage-specific MHCII expression is regulated by a remote Ciita enhancer controlled by NFAT5. J Exp Med. 2018;215:2901-2918 pubmed publisher
White J, Xiong S, Malvin N, Khoury Hanold W, Heuckeroth R, Stappenbeck T, et al. Intestinal Dysmotility Syndromes following Systemic Infection by Flaviviruses. Cell. 2018;175:1198-1212.e12 pubmed publisher
Chhatbar C, Detje C, Grabski E, Borst K, Spanier J, Ghita L, et al. Type I Interferon Receptor Signaling of Neurons and Astrocytes Regulates Microglia Activation during Viral Encephalitis. Cell Rep. 2018;25:118-129.e4 pubmed publisher
Sun K, Cheung K, Au S, Yeung S, Yeung E. Overexpression of Mechano-Growth Factor Modulates Inflammatory Cytokine Expression and Macrophage Resolution in Skeletal Muscle Injury. Front Physiol. 2018;9:999 pubmed publisher
Thurlow L, Joshi G, Richardson A. Peroxisome Proliferator-Activated Receptor γ Is Essential for the Resolution of Staphylococcus aureus Skin Infections. Cell Host Microbe. 2018;24:261-270.e4 pubmed publisher
Zukauskas A, Mrsny R, Cortés Barrantes P, Turner J, Leong J, McCormick B. Transporters MRP1 and MRP2 Regulate Opposing Inflammatory Signals To Control Transepithelial Neutrophil Migration during Streptococcus pneumoniae Lung Infection. mSphere. 2018;3: pubmed publisher
Evrard M, Kwok I, Chong S, Teng K, Becht E, Chen J, et al. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity. 2018;48:364-379.e8 pubmed publisher
Kaufmann E, Sanz J, Dunn J, Khan N, Mendonça L, Pacis A, et al. BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis. Cell. 2018;172:176-190.e19 pubmed publisher
Riffelmacher T, Clarke A, Richter F, Stranks A, Pandey S, Danielli S, et al. Autophagy-Dependent Generation of Free Fatty Acids Is Critical for Normal Neutrophil Differentiation. Immunity. 2017;47:466-480.e5 pubmed publisher
Nair S, Poddar S, Shimak R, Diamond M. Interferon Regulatory Factor 1 Protects against Chikungunya Virus-Induced Immunopathology by Restricting Infection in Muscle Cells. J Virol. 2017;91: pubmed publisher
Pan W, Zhu S, Qu K, Meeth K, Cheng J, He K, et al. The DNA Methylcytosine Dioxygenase Tet2 Sustains Immunosuppressive Function of Tumor-Infiltrating Myeloid Cells to Promote Melanoma Progression. Immunity. 2017;47:284-297.e5 pubmed publisher
Liao Y, Liu X, Huang Y, Huang H, Lu Y, Zhang Y, et al. Expression pattern of CD11c on lung immune cells after disseminated murine cytomegalovirus infection. Virol J. 2017;14:132 pubmed publisher
Katsura A, Tamura Y, Hokari S, Harada M, Morikawa M, Sakurai T, et al. ZEB1-regulated inflammatory phenotype in breast cancer cells. Mol Oncol. 2017;11:1241-1262 pubmed publisher
Lechner A, Driver I, Lee J, Conroy C, Nagle A, Locksley R, et al. Recruited Monocytes and Type 2 Immunity Promote Lung Regeneration following Pneumonectomy. Cell Stem Cell. 2017;21:120-134.e7 pubmed publisher
Ling Y, Krishnan S, Chan C, Diep H, Ferens D, Chin Dusting J, et al. Anakinra reduces blood pressure and renal fibrosis in one kidney/DOCA/salt-induced hypertension. Pharmacol Res. 2017;116:77-86 pubmed publisher
Martins R, Maier J, Gorki A, Huber K, Sharif O, Starkl P, et al. Heme drives hemolysis-induced susceptibility to infection via disruption of phagocyte functions. Nat Immunol. 2016;17:1361-1372 pubmed publisher
Philip N, DeLaney A, Peterson L, Santos Marrero M, Grier J, Sun Y, et al. Activity of Uncleaved Caspase-8 Controls Anti-bacterial Immune Defense and TLR-Induced Cytokine Production Independent of Cell Death. PLoS Pathog. 2016;12:e1005910 pubmed publisher
Alexander K, Raggatt L, Millard S, Batoon L, Chiu Ku Wu A, Chang M, et al. Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunol Cell Biol. 2017;95:7-16 pubmed publisher
Denk F, Crow M, Didangelos A, Lopes D, McMahon S. Persistent Alterations in Microglial Enhancers in a Model of Chronic Pain. Cell Rep. 2016;15:1771-81 pubmed publisher
Upadhya R, Lam W, Maybruck B, Specht C, Levitz S, Lodge J. Induction of Protective Immunity to Cryptococcal Infection in Mice by a Heat-Killed, Chitosan-Deficient Strain of Cryptococcus neoformans. MBio. 2016;7: pubmed publisher
Yin S, Jian F, Chen Y, Chien S, Hsieh M, Hsiao P, et al. Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis. Nat Commun. 2016;7:11311 pubmed publisher
Chen F, Cao A, Yao S, Evans Marin H, Liu H, Wu W, et al. mTOR Mediates IL-23 Induction of Neutrophil IL-17 and IL-22 Production. J Immunol. 2016;196:4390-9 pubmed publisher
Dudek M, Puttur F, Arnold Schrauf C, Kühl A, Holzmann B, Henriques Normark B, et al. Lung epithelium and myeloid cells cooperate to clear acute pneumococcal infection. Mucosal Immunol. 2016;9:1288-302 pubmed publisher
Lee J, Kang J, Boo H, Hwang S, Hong S, Lee S, et al. STAT3-mediated IGF-2 secretion in the tumour microenvironment elicits innate resistance to anti-IGF-1R antibody. Nat Commun. 2015;6:8499 pubmed publisher
Gabbita S, Johnson M, Kobritz N, Eslami P, Poteshkina A, Varadarajan S, et al. Oral TNFα Modulation Alters Neutrophil Infiltration, Improves Cognition and Diminishes Tau and Amyloid Pathology in the 3xTgAD Mouse Model. PLoS ONE. 2015;10:e0137305 pubmed publisher
Furuya Y, Furuya A, Roberts S, Sanfilippo A, Salmon S, Metzger D. Prevention of Influenza Virus-Induced Immunopathology by TGF-β Produced during Allergic Asthma. PLoS Pathog. 2015;11:e1005180 pubmed publisher
Galvani S, Sanson M, Blaho V, Swendeman S, Obinata H, Conger H, et al. HDL-bound sphingosine 1-phosphate acts as a biased agonist for the endothelial cell receptor S1P1 to limit vascular inflammation. Sci Signal. 2015;8:ra79 pubmed publisher
Douglas T, Champagne C, Morizot A, Lapointe J, Saleh M. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice. J Immunol. 2015;195:2365-73 pubmed publisher
Almishri W, Deans J, Swain M. Rapid activation and hepatic recruitment of innate-like regulatory B cells after invariant NKT cell stimulation in mice. J Hepatol. 2015;63:943-51 pubmed publisher
Moore J, Vinh A, Tuck K, Sakkal S, Krishnan S, Chan C, et al. M2 macrophage accumulation in the aortic wall during angiotensin II infusion in mice is associated with fibrosis, elastin loss, and elevated blood pressure. Am J Physiol Heart Circ Physiol. 2015;309:H906-17 pubmed publisher
Copenhaver A, Casson C, Nguyen H, Duda M, Shin S. IL-1R signaling enables bystander cells to overcome bacterial blockade of host protein synthesis. Proc Natl Acad Sci U S A. 2015;112:7557-62 pubmed publisher
Eastman A, He X, Qiu Y, Davis M, Vedula P, Lyons D, et al. Cryptococcal heat shock protein 70 homolog Ssa1 contributes to pulmonary expansion of Cryptococcus neoformans during the afferent phase of the immune response by promoting macrophage M2 polarization. J Immunol. 2015;194:5999-6010 pubmed publisher
Sanfilippo A, Furuya Y, Roberts S, Salmon S, Metzger D. Allergic Lung Inflammation Reduces Tissue Invasion and Enhances Survival from Pulmonary Pneumococcal Infection in Mice, Which Correlates with Increased Expression of Transforming Growth Factor β1 and SiglecF(low) Alveolar Macrophages. Infect Immun. 2015;83:2976-83 pubmed publisher
Mylonas K, Jenkins S, Castellan R, Rückerl D, McGregor K, Phythian Adams A, et al. The adult murine heart has a sparse, phagocytically active macrophage population that expands through monocyte recruitment and adopts an 'M2' phenotype in response to Th2 immunologic challenge. Immunobiology. 2015;220:924-33 pubmed publisher
Esser von Bieren J, Volpe B, Kulagin M, Sutherland D, Guiet R, Seitz A, et al. Antibody-mediated trapping of helminth larvae requires CD11b and Fcγ receptor I. J Immunol. 2015;194:1154-63 pubmed publisher
Her Z, Teng T, Tan J, Teo T, Kam Y, Lum F, et al. Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response. EMBO Mol Med. 2015;7:24-41 pubmed publisher
Zasłona Z, Przybranowski S, Wilke C, Van Rooijen N, Teitz Tennenbaum S, Osterholzer J, et al. Resident alveolar macrophages suppress, whereas recruited monocytes promote, allergic lung inflammation in murine models of asthma. J Immunol. 2014;193:4245-53 pubmed publisher
McCartney Francis N, Jin W, Belkaid Y, McGrady G, Wahl S. Aberrant host defense against Leishmania major in the absence of SLPI. J Leukoc Biol. 2014;96:917-29 pubmed publisher
Coquery C, Wade N, Loo W, Kinchen J, Cox K, Jiang C, et al. Neutrophils contribute to excess serum BAFF levels and promote CD4+ T cell and B cell responses in lupus-prone mice. PLoS ONE. 2014;9:e102284 pubmed publisher
Furuya Y, Roberts S, Hurteau G, Sanfilippo A, Racine R, Metzger D. Asthma increases susceptibility to heterologous but not homologous secondary influenza. J Virol. 2014;88:9166-81 pubmed publisher
Bryant J, Lerret N, Wang J, Kang H, Tasch J, Zhang Z, et al. Preemptive donor apoptotic cell infusions induce IFN-?-producing myeloid-derived suppressor cells for cardiac allograft protection. J Immunol. 2014;192:6092-101 pubmed publisher
Johansson J, Pradhan S, Lokteva L, Woodling N, Ko N, Brown H, et al. Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia. J Neurosci. 2013;33:16016-32 pubmed publisher
Park Y, Song B, Kim Y, Kim E, Lee J, Lee G, et al. Tumor microenvironmental conversion of natural killer cells into myeloid-derived suppressor cells. Cancer Res. 2013;73:5669-81 pubmed publisher
Chan C, Moore J, Budzyn K, Guida E, Diep H, Vinh A, et al. Reversal of vascular macrophage accumulation and hypertension by a CCR2 antagonist in deoxycorticosterone/salt-treated mice. Hypertension. 2012;60:1207-12 pubmed publisher
Ng L, Qin J, Roediger B, Wang Y, Jain R, Cavanagh L, et al. Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events. J Invest Dermatol. 2011;131:2058-68 pubmed publisher
Fujita M, Kohanbash G, Fellows Mayle W, Hamilton R, Komohara Y, Decker S, et al. COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells. Cancer Res. 2011;71:2664-74 pubmed publisher
Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo M, Coffman R, et al. Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9. J Exp Med. 2010;207:2931-42 pubmed publisher
Sumagin R, Prizant H, Lomakina E, Waugh R, Sarelius I. LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ. J Immunol. 2010;185:7057-66 pubmed publisher
Tadagavadi R, REEVES W. Endogenous IL-10 attenuates cisplatin nephrotoxicity: role of dendritic cells. J Immunol. 2010;185:4904-11 pubmed publisher
Daley J, Thomay A, Connolly M, Reichner J, Albina J. Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice. J Leukoc Biol. 2008;83:64-70 pubmed
product information
Antigen :
Ly-6G
Apps. Abbrev. :
FC
Cat # :
127618
Clone :
1A8
Item :
PE/Cyanine7 anti-mouse Ly-6G
Isotype :
Rat IgG2a, κ
Other Names :
Lymphocyte antigen 6 complex, locus G
Size :
100 μg
Price (USD) :
303 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE_CYANINE7
Immunogen :
Ly-6G transfected EL-4J cell line.
Application Notes :
While 1A8 recognizes only Ly-6G, clone RB6-8C5 recognizes both Ly-6G and Ly-6C. Clone RB6-8C5 binds with high affinity to mouse Ly-6G molecules and to a lower extent to Ly-6C^15. Clone RB6-8C5 impairs the binding of anti-mouse Ly-6G clone 1A8^15. However, clone RB6-8C5 is able to stain in the presence of anti-mouse Ly-6C clone HK1.4^16.Additional reported applications (for the relevant formats) include: immunohistochemistry^9 of frozen sections^10 and paraffin-embedded sections^11, depletion^4, 12-14, and spatial biology (IBEX)^20,21. The Ultra-LEAF™ purified antibody (Endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for in vivo studies or highly sensitive assays (Cat. No. 127632, 127649, 127650, 127661 and 127662).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA