product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse IFNAR-1
catalog :
127311
quantity :
25 μg
price :
134 USD
clonality :
monoclonal
host :
mouse
conjugate :
PE
clone name :
MAR1-5A3
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 15
Reference
Marques da Silva C, Peissig K, Walker M, Shiau J, Bowers C, Kyle D, et al. Direct type I interferon signaling in hepatocytes controls malaria. Cell Rep. 2022;40:111098 pubmed publisher
Li C, Wang G, Sivasami P, Ramirez R, Zhang Y, Benoist C, et al. Interferon-α-producing plasmacytoid dendritic cells drive the loss of adipose tissue regulatory T cells during obesity. Cell Metab. 2021;33:1610-1623.e5 pubmed publisher
Gui J, Zahedi F, Ortiz A, Cho C, Katlinski K, Alicea Torres K, et al. Activation of p38α stress-activated protein kinase drives the formation of the pre-metastatic niche in the lungs. Nat Cancer. 2020;1:603-619 pubmed publisher
Melo Silva C, Alves Peixoto P, Heath N, Tang L, Montoya B, Knudson C, et al. Resistance to lethal ectromelia virus infection requires Type I interferon receptor in natural killer cells and monocytes but not in adaptive immune or parenchymal cells. PLoS Pathog. 2021;17:e1009593 pubmed publisher
Tuttle K, Waugh K, Araya P, Minter R, Orlicky D, Ludwig M, et al. JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome. Cell Rep. 2020;33:108407 pubmed publisher
Soni C, Perez O, Voss W, Pucella J, Serpas L, Mehl J, et al. Plasmacytoid Dendritic Cells and Type I Interferon Promote Extrafollicular B Cell Responses to Extracellular Self-DNA. Immunity. 2020;52:1022-1038.e7 pubmed publisher
Tsuchiya N, Zhang R, Iwama T, Ueda N, Liu T, Tatsumi M, et al. Type I Interferon Delivery by iPSC-Derived Myeloid Cells Elicits Antitumor Immunity via XCR1+ Dendritic Cells. Cell Rep. 2019;29:162-175.e9 pubmed publisher
Bradley K, Finsterbusch K, Schnepf D, Crotta S, Llorian M, Davidson S, et al. Microbiota-Driven Tonic Interferon Signals in Lung Stromal Cells Protect from Influenza Virus Infection. Cell Rep. 2019;28:245-256.e4 pubmed publisher
Banks D, Ahlbrand S, Hughitt V, Shah S, Mayer Barber K, Vogel S, et al. Mycobacterium tuberculosis Inhibits Autocrine Type I IFN Signaling to Increase Intracellular Survival. J Immunol. 2019;: pubmed publisher
Ortiz A, Gui J, Zahedi F, Yu P, Cho C, Bhattacharya S, et al. An Interferon-Driven Oxysterol-Based Defense against Tumor-Derived Extracellular Vesicles. Cancer Cell. 2019;35:33-45.e6 pubmed publisher
Kamada R, Yang W, Zhang Y, Patel M, Yang Y, Ouda R, et al. Interferon stimulation creates chromatin marks and establishes transcriptional memory. Proc Natl Acad Sci U S A. 2018;115:E9162-E9171 pubmed publisher
Hamilton J, Wu Q, Yang P, Luo B, Liu S, Hong H, et al. Cutting Edge: Endogenous IFN-β Regulates Survival and Development of Transitional B Cells. J Immunol. 2017;199:2618-2623 pubmed publisher
Hamner M, Ye Z, Lee R, Colman J, Le T, Gong D, et al. Ischemic Preconditioning in White Matter: Magnitude and Mechanism. J Neurosci. 2015;35:15599-611 pubmed publisher
Rautela J, Baschuk N, Slaney C, Jayatilleke K, Xiao K, Bidwell B, et al. Loss of Host Type-I IFN Signaling Accelerates Metastasis and Impairs NK-cell Antitumor Function in Multiple Models of Breast Cancer. Cancer Immunol Res. 2015;3:1207-17 pubmed publisher
Dong H, Franklin N, Roberts D, Yagita H, Glennie M, Bullock T. CD27 stimulation promotes the frequency of IL-7 receptor-expressing memory precursors and prevents IL-12-mediated loss of CD8(+) T cell memory in the absence of CD4(+) T cell help. J Immunol. 2012;188:3829-38 pubmed publisher
product information
Antigen :
IFNAR-1
Apps. Abbrev. :
FC
Cat # :
127311
Clone :
MAR1-5A3
Item :
PE anti-mouse IFNAR-1
Isotype :
Mouse IgG1, κ
Other Names :
IFNAR1, IFN-αR1, IFN-α/β Receptor Subunit 1
Size :
25 μg
Price (USD) :
134 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
PE
Immunogen :
Exogenously expressed murine IFNAR1 extracellular domain
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting^1,2, immunoprecipitation^1, ELISA^1, and blocking^8,9. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 127322) (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA