product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Biotin anti-mouse IFNAR-1
catalog :
127305
quantity :
25 μg
price :
89 USD
clonality :
monoclonal
host :
mouse
conjugate :
biotin
clone name :
MAR1-5A3
reactivity :
mouse
application :
western blot, ELISA, immunoprecipitation, flow cytometry, immunohistochemistry knockout validation
more info or order :
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; fig s1a
Daniels B, Jujjavarapu H, Durrant D, Williams J, Green R, White J, et al. Regional astrocyte IFN signaling restricts pathogenesis during neurotropic viral infection. J Clin Invest. 2017;127:843-856 pubmed publisher
Tu X, Chu T, Jeltema D, Abbott K, Yang K, Xing C, et al. Interruption of post-Golgi STING trafficking activates tonic interferon signaling. Nat Commun. 2022;13:6977 pubmed publisher
Zhou Y, Fei M, Zhang G, Liang W, Lin W, Wu Y, et al. Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP. Immunity. 2020;52:357-373.e9 pubmed publisher
Marshall H, Urban S, Welsh R. Virus-induced transient immune suppression and the inhibition of T cell proliferation by type I interferon. J Virol. 2011;85:5929-39 pubmed publisher
Swanson C, Wilson T, Strauch P, Colonna M, Pelanda R, Torres R. Type I IFN enhances follicular B cell contribution to the T cell-independent antibody response. J Exp Med. 2010;207:1485-500 pubmed publisher
Kelly Scumpia K, Scumpia P, Delano M, Weinstein J, Cuenca A, Wynn J, et al. Type I interferon signaling in hematopoietic cells is required for survival in mouse polymicrobial sepsis by regulating CXCL10. J Exp Med. 2010;207:319-26 pubmed publisher
Habjan M, Pichlmair A, Elliott R, Overby A, Glatter T, Gstaiger M, et al. NSs protein of rift valley fever virus induces the specific degradation of the double-stranded RNA-dependent protein kinase. J Virol. 2009;83:4365-75 pubmed publisher
Miller J, Ma Y, Bian J, Sheehan K, Zachary J, Weis J, et al. A critical role for type I IFN in arthritis development following Borrelia burgdorferi infection of mice. J Immunol. 2008;181:8492-503 pubmed
product information
Antigen :
IFNAR-1
Apps. Abbrev. :
FC, IP, WB, ELISA
Cat # :
127305
Clone :
MAR1-5A3
Item :
Biotin anti-mouse IFNAR-1
Isotype :
Mouse IgG1, κ
Other Names :
IFNAR1, IFN-αR1, IFN-α/β Receptor Subunit 1
Size :
25 μg
Price (USD) :
89 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Mouse
Conjugate/Tag/Label :
BIOTIN
Immunogen :
Exogenously expressed murine IFNAR1 extracellular domain
Application Notes :
Additional reported applications (for the relevant formats) include: Western blotting^1,2, immunoprecipitation^1, ELISA^1, and blocking^8,9. For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 127322) (Endotoxin <0.01 EU/µg).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA