product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
FITC anti-mouse CD8b (Ly-3)
catalog :
126606
quantity :
500 μg
price :
235 USD
clonality :
monoclonal
host :
rat
conjugate :
FITC
clone name :
YTS156.7.7
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1a, 1c, 1d, 5d, s5a
Nelson C, Thompson E, Quarnstrom C, Fraser K, Seelig D, Bhela S, et al. Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens. Cell Rep. 2019;28:3092-3104.e5 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s2f, s2g
LaFleur M, Nguyen T, Coxe M, Yates K, Trombley J, Weiss S, et al. A CRISPR-Cas9 delivery system for in vivo screening of genes in the immune system. Nat Commun. 2019;10:1668 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3e
Cornelissen L, Blanas A, van der Horst J, Kruijssen L, Zaal A, O Toole T, et al. Disruption of sialic acid metabolism drives tumor growth by augmenting CD8+ T cell apoptosis. Int J Cancer. 2019;144:2290-2302 pubmed publisher
  • flow cytometry; mouse; fig 2a
Borger J, Zamoyska R, Gakamsky D. Proximity of TCR and its CD8 coreceptor controls sensitivity of T cells. Immunol Lett. 2014;157:16-22 pubmed publisher
Wang Y, Cao Y, Pan C, Zhou Z, Yang L, Lusis A. Intestinal cell type-specific communication networks underlie homeostasis and response to Western diet. J Exp Med. 2023;220: pubmed publisher
Dean J, Helm E, Fu Z, Xiong L, Sun N, Oliff K, et al. The aryl hydrocarbon receptor cell intrinsically promotes resident memory CD8+ T cell differentiation and function. Cell Rep. 2023;42:111963 pubmed publisher
Christian D, Adams T, Shallberg L, Phan A, Smith T, Abraha M, et al. cDC1 coordinate innate and adaptive responses in the omentum required for T cell priming and memory. Sci Immunol. 2022;7:eabq7432 pubmed publisher
Takaku S, Shimizu M, Morita R. Japanese Kampo Medicine Juzentaihoto Improves Antiviral Cellular Immunity in Tumour-Bearing Hosts. Evid Based Complement Alternat Med. 2022;2022:6122955 pubmed publisher
Xiong T, He P, Zhou M, Zhong D, Yang T, He W, et al. Glutamate blunts cell-killing effects of neutrophils in tumor microenvironment. Cancer Sci. 2022;113:1955-1967 pubmed publisher
Guo Y, Xie Y, Gao M, Zhao Y, Franco F, Wenes M, et al. Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity. Nat Immunol. 2021;22:746-756 pubmed publisher
Moon S, Park Y, Hyeon S, Kim Y, Kim J, Kim H, et al. Niche-specific MHC II and PD-L1 regulate CD4+CD8αα+ intraepithelial lymphocyte differentiation. J Exp Med. 2021;218: pubmed publisher
Mardomi A, Limoni S, Rahbarghazi R, Mohammadi N, Khorashadizadeh M, Ranjbaran H, et al. PD-L1 overexpression conveys tolerance of mesenchymal stem cell-derived cardiomyocyte-like cells in an allogeneic mouse model. J Cell Physiol. 2021;236:6328-6343 pubmed publisher
Ringel A, Drijvers J, Baker G, Catozzi A, García Cañaveras J, Gassaway B, et al. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020;183:1848-1866.e26 pubmed publisher
Drijvers J, Gillis J, Muijlwijk T, Nguyen T, Gaudiano E, Harris I, et al. Pharmacologic Screening Identifies Metabolic Vulnerabilities of CD8+ T Cells. Cancer Immunol Res. 2021;9:184-199 pubmed publisher
Lee Chang C, Miska J, Hou D, Rashidi A, Zhang P, Burga R, et al. Activation of 4-1BBL+ B cells with CD40 agonism and IFNγ elicits potent immunity against glioblastoma. J Exp Med. 2021;218: pubmed publisher
Viaud M, Abdel Wahab O, Gall J, Ivanov S, Guinamard R, Sore S, et al. ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms. Cell Rep. 2020;30:3397-3410.e5 pubmed publisher
LaFleur M, Nguyen T, Coxe M, Miller B, Yates K, Gillis J, et al. PTPN2 regulates the generation of exhausted CD8+ T cell subpopulations and restrains tumor immunity. Nat Immunol. 2019;20:1335-1347 pubmed publisher
Bianchi J, Murigneux V, Bedora Faure M, Lescale C, Deriano L. Breakage-Fusion-Bridge Events Trigger Complex Genome Rearrangements and Amplifications in Developmentally Arrested T Cell Lymphomas. Cell Rep. 2019;27:2847-2858.e4 pubmed publisher
Misumi I, Cook K, Mitchell J, Lund M, Vick S, Lee R, et al. Identification of a Locus in Mice that Regulates the Collateral Damage and Lethality of Virus Infection. Cell Rep. 2019;27:1387-1396.e5 pubmed publisher
Misumi I, Starmer J, Uchimura T, Beck M, Magnuson T, Whitmire J. Obesity Expands a Distinct Population of T Cells in Adipose Tissue and Increases Vulnerability to Infection. Cell Rep. 2019;27:514-524.e5 pubmed publisher
Wells A, Daniels K, Angelou C, Fagerberg E, Burnside A, Markstein M, et al. Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells. elife. 2017;6: pubmed publisher
do Canto F, Campos S, Granato A, da Silva R, de Paiva L, Nóbrega A, et al. Enlarged colitogenic T cell population paradoxically supports colitis prevention through the B-lymphocyte-dependent peripheral generation of CD4(+)Foxp3(+) Treg cells. Sci Rep. 2016;6:28573 pubmed publisher
Nakagawa Y, Shimizu M, Norose Y, Takahashi M, Takahashi H. Induction of rapid apoptosis for class I MHC molecule-restricted CD8(+) HIV-1 gp160-specific murine activated CTLs by free antigenic peptide in vivo. Int Immunol. 2013;25:11-24 pubmed publisher
product information
Antigen :
CD8beta
Apps. Abbrev. :
FC
Cat # :
126606
Clone :
YTS156.7.7
Item :
FITC anti-mouse CD8b (Ly-3)
Isotype :
Rat IgG2b, κ
Other Names :
Lyt-3, Ly-3
Size :
500 μg
Price (USD) :
235 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
FITC
Immunogen :
Mouse thymocytes
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen tissue sections.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA