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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse CD183 (CXCR3)
catalog :
126502
quantity :
200 μg
price :
118 USD
clonality :
monoclonal
host :
hamsters
conjugate :
nonconjugated
clone name :
CXCR3-173
reactivity :
mouse
application :
neutralization, flow cytometry, immunohistochemistry - frozen section, mass cytometry
more info or order :
citations: 53
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed publisher
  • flow cytometry; mouse
Hutton C, Heider F, Blanco Gómez A, Banyard A, Kononov A, Zhang X, et al. Single-cell analysis defines a pancreatic fibroblast lineage that supports anti-tumor immunity. Cancer Cell. 2021;: pubmed publisher
  • mass cytometry; mouse; loading ...
Joseph R, Soundararajan R, Vasaikar S, Yang F, Allton K, Tian L, et al. CD8+ T cells inhibit metastasis and CXCL4 regulates its function. Br J Cancer. 2021;125:176-189 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:80; loading ...; fig 8e
Pein M, Insua Rodríguez J, Hongu T, Riedel A, Meier J, Wiedmann L, et al. Metastasis-initiating cells induce and exploit a fibroblast niche to fuel malignant colonization of the lungs. Nat Commun. 2020;11:1494 pubmed publisher
  • flow cytometry; mouse; loading ...; fig e3k
Karmaus P, Chen X, Lim S, Herrada A, Nguyen T, Xu B, et al. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. Nature. 2019;565:101-105 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4g
Moalli F, Ficht X, Germann P, Vladymyrov M, Stolp B, de Vries I, et al. The Rho regulator Myosin IXb enables nonlymphoid tissue seeding of protective CD8+ T cells. J Exp Med. 2018;215:1869-1890 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4a
Xiao F, Ai G, Yan W, Wan X, Luo X, Ning Q. Intrahepatic recruitment of cytotoxic NK cells contributes to autoimmune hepatitis progression. Cell Immunol. 2018;327:13-20 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4k
Ramos G, van den Berg A, Nunes Silva V, Weirather J, Peters L, Burkard M, et al. Myocardial aging as a T-cell-mediated phenomenon. Proc Natl Acad Sci U S A. 2017;114:E2420-E2429 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1e
Chamoto K, Chowdhury P, Kumar A, Sonomura K, Matsuda F, Fagarasan S, et al. Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity. Proc Natl Acad Sci U S A. 2017;114:E761-E770 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s7e
van der Weyden L, Arends M, Campbell A, Bald T, Wardle Jones H, Griggs N, et al. Genome-wide in vivo screen identifies novel host regulators of metastatic colonization. Nature. 2017;541:233-236 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Ma C, Mishra S, Demel E, Liu Y, Zhang N. TGF-? Controls the Formation of Kidney-Resident T Cells via Promoting Effector T Cell Extravasation. J Immunol. 2017;198:749-756 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5a
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  • flow cytometry; mouse; loading ...; fig 4f
Barin J, Talor M, Schaub J, Diny N, Hou X, Hoyer M, et al. Collaborative Interferon-? and Interleukin-17 Signaling Protects the Oral Mucosa from Staphylococcus aureus. Am J Pathol. 2016;186:2337-52 pubmed publisher
  • flow cytometry; mouse
Pearce V, Bouabe H, MacQueen A, Carbonaro V, Okkenhaug K. PI3Kδ Regulates the Magnitude of CD8+ T Cell Responses after Challenge with Listeria monocytogenes. J Immunol. 2015;195:3206-17 pubmed publisher
  • flow cytometry; mouse
Boding L, Hansen A, Nielsen M, Meroni G, Braunstein T, Woetmann A, et al. Midline 1 controls polarization and migration of murine cytotoxic T cells. Immun Inflamm Dis. 2014;2:262-71 pubmed publisher
  • flow cytometry; mouse; fig 6
Van Den Ham K, Shio M, Rainone A, Fournier S, Krawczyk C, Olivier M. Iron prevents the development of experimental cerebral malaria by attenuating CXCR3-mediated T cell chemotaxis. PLoS ONE. 2015;10:e0118451 pubmed publisher
  • flow cytometry; mouse
Rao E, Zhang Y, Zhu G, Hao J, Persson X, Egilmez N, et al. Deficiency of AMPK in CD8+ T cells suppresses their anti-tumor function by inducing protein phosphatase-mediated cell death. Oncotarget. 2015;6:7944-58 pubmed
  • flow cytometry; mouse; fig 3
Huang Y, Clarke F, Karimi M, Roy N, Williamson E, Okumura M, et al. CRK proteins selectively regulate T cell migration into inflamed tissues. J Clin Invest. 2015;125:1019-32 pubmed publisher
Hailemichael Y, Johnson D, Abdel Wahab N, Foo W, Bentebibel S, Daher M, et al. Interleukin-6 blockade abrogates immunotherapy toxicity and promotes tumor immunity. Cancer Cell. 2022;40:509-523.e6 pubmed publisher
Dionisio Santos D, Karaahmet B, Belcher E, Owlett L, Trojanczyk L, Olschowka J, et al. Evaluating Effects of Glatiramer Acetate Treatment on Amyloid Deposition and Tau Phosphorylation in the 3xTg Mouse Model of Alzheimer's Disease. Front Neurosci. 2021;15:758677 pubmed publisher
Uzhachenko R, Bharti V, Ouyang Z, Blevins A, Mont S, Saleh N, et al. Metabolic modulation by CDK4/6 inhibitor promotes chemokine-mediated recruitment of T cells into mammary tumors. Cell Rep. 2021;35:108944 pubmed publisher
Yu H, Yang A, Liu L, Mak J, Fairlie D, Cowley S. CXCL16 Stimulates Antigen-Induced MAIT Cell Accumulation but Trafficking During Lung Infection Is CXCR6-Independent. Front Immunol. 2020;11:1773 pubmed publisher
Zheng Z, Zhang L, Cui X, Yu X, Hsu P, Lyu R, et al. Control of Early B Cell Development by the RNA N6-Methyladenosine Methylation. Cell Rep. 2020;31:107819 pubmed publisher
Ly A, Liao Y, Pietrzak H, Ioannidis L, Sidwell T, Gloury R, et al. Transcription Factor T-bet in B Cells Modulates Germinal Center Polarization and Antibody Affinity Maturation in Response to Malaria. Cell Rep. 2019;29:2257-2269.e6 pubmed publisher
Wei S, Sharma R, Anang N, Levine J, Zhao Y, Mancuso J, et al. Negative Co-stimulation Constrains T Cell Differentiation by Imposing Boundaries on Possible Cell States. Immunity. 2019;50:1084-1098.e10 pubmed publisher
Denton A, Innocentin S, Carr E, Bradford B, Lafouresse F, Mabbott N, et al. Type I interferon induces CXCL13 to support ectopic germinal center formation. J Exp Med. 2019;216:621-637 pubmed publisher
Amir M, Chaudhari S, Wang R, Campbell S, Mosure S, Chopp L, et al. REV-ERBα Regulates TH17 Cell Development and Autoimmunity. Cell Rep. 2018;25:3733-3749.e8 pubmed publisher
Salou M, Legoux F, Gilet J, Darbois A, du Halgouet A, Alonso R, et al. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets. J Exp Med. 2019;216:133-151 pubmed publisher
Zhu Y, Padgett L, Dinh H, Marcovecchio P, Blatchley A, Wu R, et al. Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow. Cell Rep. 2018;24:2329-2341.e8 pubmed publisher
Stathopoulou C, Gangaplara A, Mallett G, Flomerfelt F, Liniany L, Knight D, et al. PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells. Immunity. 2018;49:247-263.e7 pubmed publisher
Li C, DiSpirito J, Zemmour D, Spallanzani R, Kuswanto W, Benoist C, et al. TCR Transgenic Mice Reveal Stepwise, Multi-site Acquisition of the Distinctive Fat-Treg Phenotype. Cell. 2018;174:285-299.e12 pubmed publisher
Acharya S, Timilshina M, Jiang L, Neupane S, Choi D, Park S, et al. Amelioration of Experimental autoimmune encephalomyelitis and DSS induced colitis by NTG-A-009 through the inhibition of Th1 and Th17 cells differentiation. Sci Rep. 2018;8:7799 pubmed publisher
Sumida H, Cyster J. G-Protein Coupled Receptor 18 Contributes to Establishment of the CD8 Effector T Cell Compartment. Front Immunol. 2018;9:660 pubmed publisher
Wang D, Diao H, Getzler A, Rogal W, Frederick M, Milner J, et al. The Transcription Factor Runx3 Establishes Chromatin Accessibility of cis-Regulatory Landscapes that Drive Memory Cytotoxic T Lymphocyte Formation. Immunity. 2018;48:659-674.e6 pubmed publisher
Aguilar Valenzuela R, Netland J, Seo Y, Bevan M, Grakoui A, Suthar M. Dynamics of Tissue-Specific CD8+ T Cell Responses during West Nile Virus Infection. J Virol. 2018;92: pubmed publisher
Hailemichael Y, Woods A, Fu T, He Q, Nielsen M, Hasan F, et al. Cancer vaccine formulation dictates synergy with CTLA-4 and PD-L1 checkpoint blockade therapy. J Clin Invest. 2018;128:1338-1354 pubmed publisher
Gaya M, Barral P, Burbage M, Aggarwal S, Montaner B, Warren Navia A, et al. Initiation of Antiviral B Cell Immunity Relies on Innate Signals from Spatially Positioned NKT Cells. Cell. 2018;172:517-533.e20 pubmed publisher
Capece T, Walling B, Lim K, Kim K, Bae S, Chung H, et al. A novel intracellular pool of LFA-1 is critical for asymmetric CD8+ T cell activation and differentiation. J Cell Biol. 2017;216:3817-3829 pubmed publisher
Dzutsev A, Hogg A, Sui Y, Solaymani Mohammadi S, Yu H, Frey B, et al. Differential T cell homing to colon vs. small intestine is imprinted by local CD11c+ APCs that determine homing receptors. J Leukoc Biol. 2017;102:1381-1388 pubmed publisher
Hondowicz B, Kim K, Ruterbusch M, Keitany G, Pepper M. IL-2 is required for the generation of viral-specific CD4+ Th1 tissue-resident memory cells and B cells are essential for maintenance in the lung. Eur J Immunol. 2017;: pubmed publisher
Chen Z, Stelekati E, Kurachi M, Yu S, Cai Z, Manne S, et al. miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb. Cell Rep. 2017;20:2584-2597 pubmed publisher
Wei S, Levine J, Cogdill A, Zhao Y, Anang N, Andrews M, et al. Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade. Cell. 2017;170:1120-1133.e17 pubmed publisher
Wu X, Dayanand K, Thylur R, Norbury C, Gowda D. Small molecule-based inhibition of MEK1/2 proteins dampens inflammatory responses to malaria, reduces parasite load, and mitigates pathogenic outcomes. J Biol Chem. 2017;292:13615-13634 pubmed publisher
Rabacal W, Pabbisetty S, Hoek K, Cendron D, Guo Y, Maseda D, et al. Transcription factor KLF2 regulates homeostatic NK cell proliferation and survival. Proc Natl Acad Sci U S A. 2016;113:5370-5 pubmed publisher
Smigiel K, Richards E, Srivastava S, Thomas K, Dudda J, Klonowski K, et al. CCR7 provides localized access to IL-2 and defines homeostatically distinct regulatory T cell subsets. J Exp Med. 2014;211:121-36 pubmed publisher
Seung E, CHO J, Sparwasser T, Medoff B, Luster A. Inhibiting CXCR3-dependent CD8+ T cell trafficking enhances tolerance induction in a mouse model of lung rejection. J Immunol. 2011;186:6830-8 pubmed publisher
Haworth O, Cernadas M, Levy B. NK cells are effectors for resolvin E1 in the timely resolution of allergic airway inflammation. J Immunol. 2011;186:6129-35 pubmed publisher
Haque A, Best S, Amante F, Ammerdorffer A, de Labastida F, Pereira T, et al. High parasite burdens cause liver damage in mice following Plasmodium berghei ANKA infection independently of CD8(+) T cell-mediated immune pathology. Infect Immun. 2011;79:1882-8 pubmed publisher
Dürr C, Pfeifer D, Claus R, Schmitt Graeff A, Gerlach U, Graeser R, et al. CXCL12 mediates immunosuppression in the lymphoma microenvironment after allogeneic transplantation of hematopoietic cells. Cancer Res. 2010;70:10170-81 pubmed publisher
Kimpfler S, Sevko A, Ring S, Falk C, Osen W, Frank K, et al. Skin melanoma development in ret transgenic mice despite the depletion of CD25+Foxp3+ regulatory T cells in lymphoid organs. J Immunol. 2009;183:6330-7 pubmed publisher
Sharma R, Deshmukh U, Zheng L, Fu S, Ju S. X-linked Foxp3 (Scurfy) mutation dominantly inhibits submandibular gland development and inflammation respectively through adaptive and innate immune mechanisms. J Immunol. 2009;183:3212-8 pubmed publisher
Barbi J, Snider H, Bhardwaj N, Lezama Davila C, Durbin J, Satoskar A. Signal transducer and activator of transcription 1 in T cells plays an indispensable role in immunity to Leishmania major by mediating Th1 cell homing to the site of infection. FASEB J. 2009;23:3990-9 pubmed publisher
McAleer J, Rossi R, Vella A. Lipopolysaccharide potentiates effector T cell accumulation into nonlymphoid tissues through TRIF. J Immunol. 2009;182:5322-30 pubmed publisher
product information
Antigen :
CD183
Apps. Abbrev. :
FC, Block
Cat # :
126502
Clone :
CXCR3-173
Item :
Purified anti-mouse CD183 (CXCR3)
Isotype :
Armenian Hamster IgG
Other Names :
CXCR3, G protein-coupled receptor 9 (GPR9), CKR-L2, IP10 receptor (IP10-R), Mig receptor (Mig-R )
Size :
200 μg
Price (USD) :
118 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
PURE
Immunogen :
Mouse N-terminus of CXCR3
Application Notes :
Clone CXCR3-173 does not work for Western blotting.^7 For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 126526) with endotoxin < 0.01 EU/µg, Azide-Free, 0.2 µm filtered.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA