product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 488 anti-mouse FOXP3
catalog :
126405
quantity :
25 μg
price :
188 USD
clonality :
monoclonal
host :
rat
conjugate :
AF488
clone name :
MF-14
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry
more info or order :
citations: 59
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 7b
Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s2b, s3b, s4d
Moreira T, Mangani D, Cox L, Leibowitz J, Lobo E, Oliveira M, et al. PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis. Nat Commun. 2021;12:4907 pubmed publisher
  • flow cytometry; mouse; 1:50; loading ...; fig 3f
Van De Velde L, Allen E, Crawford J, Wilson T, Guy C, Russier M, et al. Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells. Cancer Res. 2021;81:5047-5059 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a, s2b
Toyama S, Moniaga C, Nakae S, Kurosawa M, Ogawa H, Tominaga M, et al. Regulatory T Cells Exhibit Interleukin-33-Dependent Migratory Behavior during Skin Barrier Disruption. Int J Mol Sci. 2021;22: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4e
Reis M, Willis G, Fernandez Gonzalez A, Yeung V, Taglauer E, Magaletta M, et al. Mesenchymal Stromal Cell-Derived Extracellular Vesicles Restore Thymic Architecture and T Cell Function Disrupted by Neonatal Hyperoxia. Front Immunol. 2021;12:640595 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s4c
Lin X, Twelkmeyer T, Zhu D, Zhang L, Zhao Y, Zhang C, et al. Homeostatic regulation of T follicular helper and antibody response to particle antigens by IL-1Ra of medullary sinus macrophage origin. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1f
Li N, Kang Y, Wang L, Huff S, Tang R, Hui H, et al. ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment. Proc Natl Acad Sci U S A. 2020;117:20159-20170 pubmed publisher
  • flow cytometry; mouse; loading ...
Ning Y, Ding J, Sun X, Xie Y, Su M, Ma C, et al. HDAC9 deficiency promotes tumor progression by decreasing the CD8+ dendritic cell infiltration of the tumor microenvironment. J Immunother Cancer. 2020;8: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6a
Fu Y, Ding Y, Wang Q, Zhu F, Tan Y, Lu X, et al. Blood-stage malaria parasites manipulate host innate immune responses through the induction of sFGL2. Sci Adv. 2020;6:eaay9269 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 4d
Mantani P, Dunér P, Ljungcrantz I, Nilsson J, Bjorkbacka H, Fredrikson G. ILC2 transfers to apolipoprotein E deficient mice reduce the lipid content of atherosclerotic lesions. BMC Immunol. 2019;20:47 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a, 2d, s3e
Lin F, Meng X, Guo Y, Cao W, Liu W, Xia Q, et al. Epigenetic initiation of the TH17 differentiation program is promoted by Cxxc finger protein 1. Sci Adv. 2019;5:eaax1608 pubmed publisher
  • flow cytometry; mouse; fig 4f
Silva D, Yu S, Ulge U, Spangler J, Jude K, Labao Almeida C, et al. De novo design of potent and selective mimics of IL-2 and IL-15. Nature. 2019;565:186-191 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 9f
Capucha T, Koren N, Nassar M, Heyman O, Nir T, Levy M, et al. Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation. J Exp Med. 2018;215:481-500 pubmed publisher
Masle Farquhar E, Jeelall Y, White J, Bier J, Deenick E, Brink R, et al. CARD11 gain-of-function mutation drives cell-autonomous accumulation of PD-1+ ICOShigh activated T cells, T-follicular, T-regulatory and T-follicular regulatory cells. Front Immunol. 2023;14:1095257 pubmed publisher
Lo W, Kuhlmann M, Rizzuto G, Ekiz H, Kolawole E, Revelo M, et al. A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nat Immunol. 2023;24:676-689 pubmed publisher
Wang X, Zhang Q, Zhou J, Xiao Z, Liu J, Deng S, et al. T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma. J Immunother Cancer. 2023;11: pubmed publisher
Zhao M, Zhu S, Zhang D, Zhou C, Yang Z, Wang C, et al. Long-lasting postoperative analgesia with local anesthetic-loaded hydrogels prevent tumor recurrence via enhancing CD8+T cell infiltration. J Nanobiotechnology. 2023;21:50 pubmed publisher
Xu R, Jacques L, Khandaker S, Beentjes D, Leon Rios M, Wei X, et al. TNFR2+ regulatory T cells protect against bacteremic pneumococcal pneumonia by suppressing IL-17A-producing γδ T cells in the lung. Cell Rep. 2023;42:112054 pubmed publisher
Shi C, Zhang Q, Yao Y, Zeng F, Du C, Nijiati S, et al. Targeting the activity of T cells by membrane surface redox regulation for cancer theranostics. Nat Nanotechnol. 2023;18:86-97 pubmed publisher
Fonderflick L, Baudu T, Adot xe9 vi O, Guittaut M, Adami P, Delage Mourroux R. The ATG8 Family Proteins GABARAP and GABARAPL1 Target Antigen to Dendritic Cells to Prime CD4+ and CD8+ T Cells. Cells. 2022;11: pubmed publisher
Liu T, Gonzalez De Los Santos F, Rinke A, Fang C, Flaherty K, Phan S. B7H3-dependent myeloid-derived suppressor cell recruitment and activation in pulmonary fibrosis. Front Immunol. 2022;13:901349 pubmed publisher
Helm M, Loui J, Simon J, Ferrer R. Cell Population Dynamics in Wound-Induced Hair Follicle Neogenesis Model. Life (Basel). 2022;12: pubmed publisher
Hongu T, Pein M, Insua Rodr xed guez J, Gutjahr E, Mattavelli G, Meier J, et al. Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs. Nat Cancer. 2022;3:486-504 pubmed publisher
Barsoumian H, Sezen D, Menon H, Younes A, Hu Y, He K, et al. High Plus Low Dose Radiation Strategy in Combination with TIGIT and PD1 Blockade to Promote Systemic Antitumor Responses. Cancers (Basel). 2022;14: pubmed publisher
An J, Ding Y, Yu C, Li J, You S, Liu Z, et al. AMP-activated protein kinase alpha1 promotes tumor development via FOXP3 elevation in tumor-infiltrating Treg cells. iScience. 2022;25:103570 pubmed publisher
Aggarwal N, Deerhake M, DiPalma D, Shahi S, Gaggioli M, Mangalam A, et al. Secreted osteopontin from CD4+ T cells limits acute graft-versus-host disease. Cell Rep. 2021;37:110170 pubmed publisher
Hu Y, Paris S, Barsoumian H, Abana C, He K, Sezen D, et al. A radioenhancing nanoparticle mediated immunoradiation improves survival and generates long-term antitumor immune memory in an anti-PD1-resistant murine lung cancer model. J Nanobiotechnology. 2021;19:416 pubmed publisher
He X, Zhou S, Quinn B, Huang W, Jahagirdar D, Vega M, et al. Position-Scanning Peptide Libraries as Particle Immunogens for Improving CD8+ T-Cell Responses. Adv Sci (Weinh). 2021;8:e2103023 pubmed publisher
Robles Oteiza C, Ayeni D, Levy S, Homer R, Kaech S, Politi K. Elevated murine HB-EGF confers sensitivity to diphtheria toxin in EGFR-mutant lung adenocarcinoma. Dis Model Mech. 2021;14: pubmed publisher
Goldfarb Y, Givony T, Kadouri N, Dobe x161 J, Peligero Cruz C, Zalayat I, et al. Mechanistic dissection of dominant AIRE mutations in mouse models reveals AIRE autoregulation. J Exp Med. 2021;218: pubmed publisher
Freitas J, López J, Llorian C, Boroni M, Kos L. The immunosuppressive role of Edn3 overexpression in the melanoma microenvironment. Pigment Cell Melanoma Res. 2021;34:1084-1093 pubmed publisher
Ren Z, Pan L, Huang Y, Chen H, Liu Y, Liu H, et al. Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy. EMBO Mol Med. 2021;13:e14059 pubmed publisher
Nicolas Boluda A, Vaquero J, Vimeux L, Guilbert T, Barrin S, Kantari Mimoun C, et al. Tumor stiffening reversion through collagen crosslinking inhibition improves T cell migration and anti-PD-1 treatment. elife. 2021;10: pubmed publisher
Guo Y, Xie Y, Gao M, Zhao Y, Franco F, Wenes M, et al. Metabolic reprogramming of terminally exhausted CD8+ T cells by IL-10 enhances anti-tumor immunity. Nat Immunol. 2021;22:746-756 pubmed publisher
Yin Q, Yu W, Grzeskowiak C, Li J, Huang H, Guo J, et al. Nanoparticle-enabled innate immune stimulation activates endogenous tumor-infiltrating T cells with broad antigen specificities. Proc Natl Acad Sci U S A. 2021;118: pubmed publisher
Zhao J, Chen S, Zhu L, Zhang L, Liu J, Xu D, et al. Antitumor Effect and Immune Response of Nanosecond Pulsed Electric Fields in Pancreatic Cancer. Front Oncol. 2020;10:621092 pubmed publisher
Deerhake M, Danzaki K, Inoue M, Cardakli E, Nonaka T, Aggarwal N, et al. Dectin-1 limits autoimmune neuroinflammation and promotes myeloid cell-astrocyte crosstalk via Card9-independent expression of Oncostatin M. Immunity. 2021;54:484-498.e8 pubmed publisher
Sanchez Felipe L, Vercruysse T, Sharma S, Ma J, Lemmens V, Van Looveren D, et al. A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate. Nature. 2021;590:320-325 pubmed publisher
Hu H, Liang X, Li H, Du C, Hao J, Wang H, et al. The armed oncolytic adenovirus ZD55-IL-24 eradicates melanoma by turning the tumor cells from the self-state into the nonself-state besides direct killing. Cell Death Dis. 2020;11:1022 pubmed publisher
Huang W, Zhou S, He X, Chiem K, Mabrouk M, Nissly R, et al. SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination. Adv Mater. 2020;32:e2005637 pubmed publisher
Barsoumian H, Ramapriyan R, Younes A, Caetano M, Menon H, Comeaux N, et al. Low-dose radiation treatment enhances systemic antitumor immune responses by overcoming the inhibitory stroma. J Immunother Cancer. 2020;8: pubmed publisher
Tuganbaev T, Mor U, Bashiardes S, Liwinski T, Nobs S, Leshem A, et al. Diet Diurnally Regulates Small Intestinal Microbiome-Epithelial-Immune Homeostasis and Enteritis. Cell. 2020;: pubmed publisher
Chen D, Barsoumian H, Yang L, Younes A, Verma V, Hu Y, et al. SHP-2 and PD-L1 Inhibition Combined with Radiotherapy Enhances Systemic Antitumor Effects in an Anti-PD-1-Resistant Model of Non-Small Cell Lung Cancer. Cancer Immunol Res. 2020;8:883-894 pubmed publisher
Kumar R, Bunn P, Singh S, Ng S, Montes De Oca M, de Labastida Rivera F, et al. Type I Interferons Suppress Anti-parasitic Immunity and Can Be Targeted to Improve Treatment of Visceral Leishmaniasis. Cell Rep. 2020;30:2512-2525.e9 pubmed publisher
Jain A, Irizarry Caro R, McDaniel M, Chawla A, Carroll K, Overcast G, et al. T cells instruct myeloid cells to produce inflammasome-independent IL-1β and cause autoimmunity. Nat Immunol. 2020;21:65-74 pubmed publisher
Kimura S, Rickert C, Kojima L, Aburawi M, Tanimine N, Fontan F, et al. Regulatory B cells require antigen recognition for effective allograft tolerance induction. Am J Transplant. 2020;20:977-987 pubmed publisher
Imbratta C, Leblond M, Bouzourene H, Speiser D, Velin D, Verdeil G. Maf deficiency in T cells dysregulates Treg - TH17 balance leading to spontaneous colitis. Sci Rep. 2019;9:6135 pubmed publisher
Newsted D, Banerjee S, Watt K, Nersesian S, Truesdell P, Blazer L, et al. Blockade of TGF-β signaling with novel synthetic antibodies limits immune exclusion and improves chemotherapy response in metastatic ovarian cancer models. Oncoimmunology. 2019;8:e1539613 pubmed publisher
Kooreman N, Kim Y, de Almeida P, Termglinchan V, Diecke S, Shao N, et al. Autologous iPSC-Based Vaccines Elicit Anti-tumor Responses In Vivo. Cell Stem Cell. 2018;22:501-513.e7 pubmed publisher
Skuljec J, Chmielewski M, Happle C, Habener A, Busse M, Abken H, et al. Chimeric Antigen Receptor-Redirected Regulatory T Cells Suppress Experimental Allergic Airway Inflammation, a Model of Asthma. Front Immunol. 2017;8:1125 pubmed publisher
Crooks J, Gargaro M, Vacca C, Volpi C, Pirro M, Scalisi G, et al. CpG Type A Induction of an Early Protective Environment in Experimental Multiple Sclerosis. Mediators Inflamm. 2017;2017:1380615 pubmed publisher
Luck H, Tsai S, Chung J, Clemente Casares X, Ghazarian M, Revelo X, et al. Regulation of obesity-related insulin resistance with gut anti-inflammatory agents. Cell Metab. 2015;21:527-42 pubmed publisher
Boyoglu Barnum S, Chirkova T, Todd S, Barnum T, Gaston K, Jorquera P, et al. Prophylaxis with a respiratory syncytial virus (RSV) anti-G protein monoclonal antibody shifts the adaptive immune response to RSV rA2-line19F infection from Th2 to Th1 in BALB/c mice. J Virol. 2014;88:10569-83 pubmed publisher
Fazio F, Zappulla C, Notartomaso S, Busceti C, Bessede A, Scarselli P, et al. Cinnabarinic acid, an endogenous agonist of type-4 metabotropic glutamate receptor, suppresses experimental autoimmune encephalomyelitis in mice. Neuropharmacology. 2014;81:237-43 pubmed publisher
Horikoshi M, Goto D, Segawa S, Yoshiga Y, Iwanami K, Inoue A, et al. Activation of Invariant NKT cells with glycolipid ligand ?-galactosylceramide ameliorates glucose-6-phosphate isomerase peptide-induced arthritis. PLoS ONE. 2012;7:e51215 pubmed publisher
Sugiura D, Denda Nagai K, Takashima M, Murakami R, Nagai S, Takeda K, et al. Local effects of regulatory T cells in MUC1 transgenic mice potentiate growth of MUC1 expressing tumor cells in vivo. PLoS ONE. 2012;7:e44770 pubmed publisher
Nakashima H, Hamaguchi Y, Watanabe R, Ishiura N, Kuwano Y, Okochi H, et al. CD22 expression mediates the regulatory functions of peritoneal B-1a cells during the remission phase of contact hypersensitivity reactions. J Immunol. 2010;184:4637-45 pubmed publisher
Barber A, Rynda A, Sentman C. Chimeric NKG2D expressing T cells eliminate immunosuppression and activate immunity within the ovarian tumor microenvironment. J Immunol. 2009;183:6939-47 pubmed publisher
Fallarino F, Volpi C, Zelante T, Vacca C, Calvitti M, Fioretti M, et al. IDO mediates TLR9-driven protection from experimental autoimmune diabetes. J Immunol. 2009;183:6303-12 pubmed publisher
product information
Antigen :
FOXP3
Apps. Abbrev. :
ICFC, IHC
Cat # :
126405
Clone :
MF-14
Item :
Alexa Fluor® 488 anti-mouse FOXP3
Isotype :
Rat IgG2b, κ
Other Names :
Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2
Size :
25 μg
Price (USD) :
188 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A488
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA