Alexa Fluor® 488 anti-mouse/human Mac-2 (Galectin-3) | BioLegend 125410 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Alexa Fluor® 488 anti-mouse/human Mac-2 (Galectin-3)

catalog :

125410

quantity :

100 μg

price :

265 USD

clonality :

monoclonal

host :

rat

conjugate :

AF488

clone name :

M3/38

reactivity :

human, mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 14

Published Application/Species/Sample/Dilution	Reference
flow cytometry; human; 0.05 ug/ml; loading ...	Di Gregoli K, Somerville M, Bianco R, Thomas A, Frankow A, Newby A, et al. Galectin-3 Identifies a Subset of Macrophages With a Potential Beneficial Role in Atherosclerosis. Arterioscler Thromb Vasc Biol. 2020;40:1491-1509 pubmed publisher
	Aylan B, Bernard E, Pellegrino E, Botella L, Fearns A, Athanasiadi N, et al. ATG7 and ATG14 restrict cytosolic and phagosomal Mycobacterium tuberculosis replication in human macrophages. Nat Microbiol. 2023;8:803-818 pubmed publisher
	Bussi C, Heunis T, Pellegrino E, Bernard E, Bah N, Dos Santos M, et al. Lysosomal damage drives mitochondrial proteome remodelling and reprograms macrophage immunometabolism. Nat Commun. 2022;13:7338 pubmed publisher
	Blackburn C, Schilke R, Vozenilek A, Chandran S, Bamgbose T, Finck B, et al. Myeloid-associated lipin-1 transcriptional co-regulatory activity is atheroprotective. Atherosclerosis. 2021;330:76-84 pubmed publisher
	Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed publisher
	Shao Y, Chen J, Dong L, He X, Cheng R, Zhou K, et al. A Protective Effect of PPARα in Endothelial Progenitor Cells Through Regulating Metabolism. Diabetes. 2019;68:2131-2142 pubmed publisher
	Bussi C, Peralta Ramos J, Arroyo D, Gallea J, Ronchi P, Kolovou A, et al. Alpha-synuclein fibrils recruit TBK1 and OPTN to lysosomal damage sites and induce autophagy in microglial cells. J Cell Sci. 2018;131: pubmed publisher
	Alexander K, Raggatt L, Millard S, Batoon L, Chiu Ku Wu A, Chang M, et al. Resting and injury-induced inflamed periosteum contain multiple macrophage subsets that are located at sites of bone growth and regeneration. Immunol Cell Biol. 2017;95:7-16 pubmed publisher
	Reales E, BernabÃ© Rubio M, Casares Arias J, Rentero C, FernÃ¡ndez Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed publisher
	Usategui A, Criado G, Izquierdo E, del Rey M, Carreira P, Ortiz P, et al. A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis. Ann Rheum Dis. 2013;72:2018-23 pubmed publisher
	Chao C, Silverberg M, Martinez Maza O, Chi M, Abrams D, Haque R, et al. Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma. Clin Cancer Res. 2012;18:4702-12 pubmed
	Li X, Mikhalkova D, Gao E, Zhang J, Myers V, Zincarelli C, et al. Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density. Am J Physiol Heart Circ Physiol. 2011;301:H1932-40 pubmed publisher
	Jacob N, Guo S, Mathian A, Koss M, Gindea S, Putterman C, et al. B Cell and BAFF dependence of IFN-?-exaggerated disease in systemic lupus erythematosus-prone NZM 2328 mice. J Immunol. 2011;186:4984-93 pubmed publisher
	Evans C, Humphries J, Mattock K, Waltham M, Wadoodi A, Saha P, et al. Hypoxia and upregulation of hypoxia-inducible factor 1{alpha} stimulate venous thrombus recanalization. Arterioscler Thromb Vasc Biol. 2010;30:2443-51 pubmed publisher

product information

Antigen :

Mac-2

Apps. Abbrev. :

Cat # :

125410

Clone :

M3/38

Item :

Alexa Fluor® 488 anti-mouse/human Mac-2 (Galectin-3)

Isotype :

Rat IgG2a, κ

Other Names :

Galectin-3, Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, εBP

Size :

100 μg

Price (USD) :

265 USD

Reactivity :

Mouse, Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

A488

Immunogen :

Raised against galectin-3 of mouse origin

Application Notes :

Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections^3-6, Western blotting^2, immunoprecipitation^1,2, immunofluorescence^7,8, and ELISA^9.;Clone M3/38 has been reported to recognize residues 48-100 in the amino-terminal domain of galectin-3^7.;

more info or order :

BioLegend product webpage