Biotin anti-mouse/human Mac-2 (Galectin-3) | BioLegend 125404 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Biotin anti-mouse/human Mac-2 (Galectin-3)

catalog :

125404

quantity :

500 μg

price :

293 USD

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

M3/38

reactivity :

human, mouse

application :

immunohistochemistry, flow cytometry

more info or order :

BioLegend product webpage

citations: 8

Reference
Wang L, Wang D, Sonzogni O, Ke S, Wang Q, Thavamani A, et al. PARP-inhibition reprograms macrophages toward an anti-tumor phenotype. Cell Rep. 2022;41:111462 pubmed publisher
Mehta A, Cheney E, Hartl C, Pantelidou C, Oliwa M, Castrillon J, et al. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nat Cancer. 2021;2:66-82 pubmed publisher
Chen P, Zhao D, Li J, Liang X, Li J, Chang A, et al. Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma. Cancer Cell. 2019;35:868-884.e6 pubmed publisher
Petit A, Demotte N, Scheid B, Wildmann C, Bigirimana R, Gordón Alonso M, et al. A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion. Nat Commun. 2016;7:12242 pubmed publisher
Zhang X, Wan Y, Chata R, Brazzale A, Atherton J, Kostner K, et al. A pilot study to demonstrate diagnostic potential of galectin-3 levels in saliva. J Clin Pathol. 2016;69:1100-1104 pubmed publisher
Horikawa S, Ishii Y, Hamashima T, Yamamoto S, Mori H, Fujimori T, et al. PDGFRÎ± plays a crucial role in connective tissue remodeling. Sci Rep. 2015;5:17948 pubmed publisher
Demotte N, Bigirimana R, Wieërs G, Stroobant V, Squifflet J, Carrasco J, et al. A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes. Clin Cancer Res. 2014;20:1823-33 pubmed publisher
Antonopoulos A, Demotte N, Stroobant V, Haslam S, van der Bruggen P, Dell A. Loss of effector function of human cytolytic T lymphocytes is accompanied by major alterations in N- and O-glycosylation. J Biol Chem. 2012;287:11240-51 pubmed publisher

product information

Antigen :

Mac-2

Apps. Abbrev. :

FC, IHC

Cat # :

125404

Clone :

M3/38

Item :

Biotin anti-mouse/human Mac-2 (Galectin-3)

Isotype :

Rat IgG2a, κ

Other Names :

Galectin-3, Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, εBP

Size :

500 μg

Price (USD) :

293 USD

Reactivity :

Mouse, Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BIOTIN

Immunogen :

Raised against galectin-3 of mouse origin

Application Notes :

Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections^3-6, Western blotting^2, immunoprecipitation^1,2, immunofluorescence^7,8, and ELISA^9.;Clone M3/38 has been reported to recognize residues 48-100 in the amino-terminal domain of galectin-3^7.;

more info or order :

BioLegend product webpage