Biotin anti-mouse/human Mac-2 (Galectin-3) | BioLegend 125403 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Biotin anti-mouse/human Mac-2 (Galectin-3)

catalog :

125403

quantity :

50 μg

price :

83 USD

clonality :

monoclonal

host :

rat

conjugate :

biotin

clone name :

M3/38

reactivity :

human, mouse

application :

immunohistochemistry, flow cytometry, immunohistochemistry - paraffin section

more info or order :

BioLegend product webpage

citations: 15

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; loading ...; fig 7h	Chen P, Zhao D, Li J, Liang X, Li J, Chang A, et al. Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma. Cancer Cell. 2019;35:868-884.e6 pubmed publisher
	Wang L, Wang D, Sonzogni O, Ke S, Wang Q, Thavamani A, et al. PARP-inhibition reprograms macrophages toward an anti-tumor phenotype. Cell Rep. 2022;41:111462 pubmed publisher
	Mehta A, Cheney E, Hartl C, Pantelidou C, Oliwa M, Castrillon J, et al. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nat Cancer. 2021;2:66-82 pubmed publisher
	Perakakis N, Joshi A, Peradze N, Stefanakis K, Li G, Feigh M, et al. The Selective Peroxisome Proliferator-Activated Receptor Gamma Modulator CHS-131 Improves Liver Histopathology and Metabolism in a Mouse Model of Obesity and Nonalcoholic Steatohepatitis. Hepatol Commun. 2020;4:1302-1315 pubmed publisher
	Petit A, Demotte N, Scheid B, Wildmann C, Bigirimana R, Gordón Alonso M, et al. A major secretory defect of tumour-infiltrating T lymphocytes due to galectin impairing LFA-1-mediated synapse completion. Nat Commun. 2016;7:12242 pubmed publisher
	Zhang X, Wan Y, Chata R, Brazzale A, Atherton J, Kostner K, et al. A pilot study to demonstrate diagnostic potential of galectin-3 levels in saliva. J Clin Pathol. 2016;69:1100-1104 pubmed publisher
	Horikawa S, Ishii Y, Hamashima T, Yamamoto S, Mori H, Fujimori T, et al. PDGFRÎ± plays a crucial role in connective tissue remodeling. Sci Rep. 2015;5:17948 pubmed publisher
	Reales E, BernabÃ© Rubio M, Casares Arias J, Rentero C, FernÃ¡ndez Barrera J, Rangel L, et al. The MAL protein is crucial for proper membrane condensation at the ciliary base, which is required for primary cilium elongation. J Cell Sci. 2015;128:2261-70 pubmed publisher
	Demotte N, Bigirimana R, Wieërs G, Stroobant V, Squifflet J, Carrasco J, et al. A short treatment with galactomannan GM-CT-01 corrects the functions of freshly isolated human tumor-infiltrating lymphocytes. Clin Cancer Res. 2014;20:1823-33 pubmed publisher
	Usategui A, Criado G, Izquierdo E, del Rey M, Carreira P, Ortiz P, et al. A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis. Ann Rheum Dis. 2013;72:2018-23 pubmed publisher
	Chao C, Silverberg M, Martinez Maza O, Chi M, Abrams D, Haque R, et al. Epstein-Barr virus infection and expression of B-cell oncogenic markers in HIV-related diffuse large B-cell Lymphoma. Clin Cancer Res. 2012;18:4702-12 pubmed
	Antonopoulos A, Demotte N, Stroobant V, Haslam S, van der Bruggen P, Dell A. Loss of effector function of human cytolytic T lymphocytes is accompanied by major alterations in N- and O-glycosylation. J Biol Chem. 2012;287:11240-51 pubmed publisher
	Li X, Mikhalkova D, Gao E, Zhang J, Myers V, Zincarelli C, et al. Myocardial injury after ischemia-reperfusion in mice deficient in Akt2 is associated with increased cardiac macrophage density. Am J Physiol Heart Circ Physiol. 2011;301:H1932-40 pubmed publisher
	Jacob N, Guo S, Mathian A, Koss M, Gindea S, Putterman C, et al. B Cell and BAFF dependence of IFN-?-exaggerated disease in systemic lupus erythematosus-prone NZM 2328 mice. J Immunol. 2011;186:4984-93 pubmed publisher
	Evans C, Humphries J, Mattock K, Waltham M, Wadoodi A, Saha P, et al. Hypoxia and upregulation of hypoxia-inducible factor 1{alpha} stimulate venous thrombus recanalization. Arterioscler Thromb Vasc Biol. 2010;30:2443-51 pubmed publisher

product information

Antigen :

Mac-2

Apps. Abbrev. :

FC, IHC

Cat # :

125403

Clone :

M3/38

Item :

Biotin anti-mouse/human Mac-2 (Galectin-3)

Isotype :

Rat IgG2a, κ

Other Names :

Galectin-3, Mac-2, Gal-3, RL-29, galactose-specific lectin 3, CBP-35, L-34, εBP

Size :

50 μg

Price (USD) :

83 USD

Reactivity :

Mouse, Human

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BIOTIN

Immunogen :

Raised against galectin-3 of mouse origin

Application Notes :

Additional reported applications (for the relevant formats) include: immunohistochemical staining of paraffin-embedded tissue sections^3-6, Western blotting^2, immunoprecipitation^1,2, immunofluorescence^7,8, and ELISA^9.;Clone M3/38 has been reported to recognize residues 48-100 in the amino-terminal domain of galectin-3^7.;

more info or order :

BioLegend product webpage