PerCP/Cyanine5.5 anti-mouse CD274 (B7-H1, PD-L1) | BioLegend 124333 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PerCP/Cyanine5.5 anti-mouse CD274 (B7-H1, PD-L1)

catalog :

124333

quantity :

25 μg

price :

147 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

10F.9G2

reactivity :

mouse

application :

flow cytometry, immunohistochemistry - paraffin section, blocking or activating experiments

more info or order :

BioLegend product webpage

citations: 13

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig 1a, 1c, s2b, s2c	Piao W, Li L, Saxena V, Iyyathurai J, Lakhan R, Zhang Y, et al. PD-L1 signaling selectively regulates T cell lymphatic transendothelial migration. Nat Commun. 2022;13:2176 pubmed publisher
immunohistochemistry - paraffin section; mouse; fig s2	Kono M, Komatsuda H, Yamaki H, Kumai T, Hayashi R, Wakisaka R, et al. Immunomodulation via FGFR inhibition augments FGFR1 targeting T-cell based antitumor immunotherapy for head and neck squamous cell carcinoma. Oncoimmunology. 2022;11:2021619 pubmed publisher
flow cytometry; mouse; 1:250; loading ...	Thanabalasuriar A, Chiang A, Morehouse C, Camara M, Hawkins S, Keller A, et al. PD-L1+ neutrophils contribute to injury-induced infection susceptibility. Sci Adv. 2021;7: pubmed publisher
blocking or activating experiments; mouse; ; fig 4b	Zhang H, Liu P, Zhang Y, Han L, Hu Z, Cai Z, et al. Inhibition of galectin-3 augments the antitumor efficacy of PD-L1 blockade in non-small-cell lung cancer. FEBS Open Bio. 2021;11:911-920 pubmed publisher
	Wu Z, Thierry K, Bachy S, Zhang X, Gamradt P, Hernandez Vargas H, et al. Pericyte stem cells induce Ly6G+ cell accumulation and immunotherapy resistance in pancreatic cancer. EMBO Rep. 2023;24:e56524 pubmed publisher
	Duraiswamy J, Turrini R, Minasyan A, Barras D, Crespo I, Grimm A, et al. Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation. Cancer Cell. 2021;39:1623-1642.e20 pubmed publisher
	Liao Y, Wu S, Huang Y, Lo P, Chan T, Chen C, et al. NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities. Front Immunol. 2021;12:743030 pubmed publisher
	Wabitsch S, Tandon M, Ruf B, Zhang Q, McCallen J, McVey J, et al. Anti-PD-1 in Combination With Trametinib Suppresses Tumor Growth and Improves Survival of Intrahepatic Cholangiocarcinoma in Mice. Cell Mol Gastroenterol Hepatol. 2021;12:1166-1178 pubmed publisher
	Zhang Z, Huang X, Wang E, Huang Y, Yang R. Identification and characterization of B220+/B220- subpopulations in murine Gr1+CD11b+ cells during tumorigenesis. Oncoimmunology. 2021;10:1912472 pubmed publisher
	Rodriguez Garcia A, Lynn R, Poussin M, Eiva M, Shaw L, O Connor R, et al. CAR-T cell-mediated depletion of immunosuppressive tumor-associated macrophages promotes endogenous antitumor immunity and augments adoptive immunotherapy. Nat Commun. 2021;12:877 pubmed publisher
	Tilstra J, Avery L, Menk A, Gordon R, Smita S, Kane L, et al. Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted. J Clin Invest. 2018;128:4884-4897 pubmed publisher
	Vendetti F, Karukonda P, Clump D, Teo T, Lalonde R, Nugent K, et al. ATR kinase inhibitor AZD6738 potentiates CD8+ T cell-dependent antitumor activity following radiation. J Clin Invest. 2018;128:3926-3940 pubmed publisher
	Panduro M, Benoist C, Mathis D. Treg cells limit IFN-? production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proc Natl Acad Sci U S A. 2018;115:E2585-E2593 pubmed publisher

product information

Antigen :

CD274

Apps. Abbrev. :

Cat # :

124333

Clone :

10F.9G2

Item :

PerCP/Cyanine5.5 anti-mouse CD274 (B7-H1, PD-L1)

Isotype :

Rat IgG2b, κ

Other Names :

B7-H1, PD-L1

Size :

25 μg

Price (USD) :

147 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PERCP_CYANINE5.5

Application Notes :

Additional reported applications (for the relevant formats) include: immunofluorescence^4, blocking^6,7,8,9, and immunohistochemistry of acetone-fixed frozen sections^4, 11. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 124303). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 124318) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin <0.01 EU/µg).;

more info or order :

BioLegend product webpage