product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD122 (IL-2Rβ)
catalog :
123210
quantity :
100 μg
price :
214 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
TM-β1
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 15
Reference
Li D, Ji W, Wei D, Gu A, Song Z, Fang W, et al. Cytochrome P450 26A1 regulates the clusters and killing activity of NK cells during the peri-implantation period. J Cell Mol Med. 2022;26:2438-2450 pubmed publisher
Reyes R, Zhang C, Deng Y, Ji N, Mukherjee N, Padrón A, et al. CD122-targeted interleukin-2 and αPD-L1 treat bladder cancer and melanoma via distinct mechanisms, including CD122-driven natural killer cell maturation. Oncoimmunology. 2021;10:2006529 pubmed publisher
Long L, Wei J, Lim S, Raynor J, Shi H, Connelly J, et al. CRISPR screens unveil signal hubs for nutrient licensing of T cell immunity. Nature. 2021;600:308-313 pubmed publisher
De Simone G, Andreata F, Blériot C, Fumagalli V, Laura C, Garcia Manteiga J, et al. Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming. Immunity. 2021;54:2089-2100.e8 pubmed publisher
Yue X, Samaniego Castruita D, Gonz xe1 lez Avalos E, Li X, Barwick B, Rao A. Whole-genome analysis of TET dioxygenase function in regulatory T cells. EMBO Rep. 2021;22:e52716 pubmed publisher
Jandke A, Melandri D, Monin L, Ushakov D, Laing A, Vantourout P, et al. Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial γδ T cell compartments. Nat Commun. 2020;11:3769 pubmed publisher
Sagar -, Pokrovskii M, Herman J, Naik S, Sock E, Zeis P, et al. Deciphering the regulatory landscape of fetal and adult γδ T-cell development at single-cell resolution. EMBO J. 2020;39:e104159 pubmed publisher
Tomala J, Spangler J. Characterization of Immune Cell Subset Expansion in Response to Therapeutic Treatment in Mice. Methods Mol Biol. 2020;2111:101-114 pubmed publisher
Schadt L, Sparano C, Schweiger N, Silina K, Cecconi V, Lucchiari G, et al. Cancer-Cell-Intrinsic cGAS Expression Mediates Tumor Immunogenicity. Cell Rep. 2019;29:1236-1248.e7 pubmed publisher
Fan M, Low J, Tanimine N, Finn K, Priyadharshini B, Germana S, et al. Differential Roles of IL-2 Signaling in Developing versus Mature Tregs. Cell Rep. 2018;25:1204-1213.e4 pubmed publisher
Sekiya T, Hibino S, Saeki K, Kanamori M, Takaki S, Yoshimura A. Nr4a Receptors Regulate Development and Death of Labile Treg Precursors to Prevent Generation of Pathogenic Self-Reactive Cells. Cell Rep. 2018;24:1627-1638.e6 pubmed publisher
Lu Y, Wang Q, Xue G, Bi E, Ma X, Wang A, et al. Th9 Cells Represent a Unique Subset of CD4+ T Cells Endowed with the Ability to Eradicate Advanced Tumors. Cancer Cell. 2018;33:1048-1060.e7 pubmed publisher
Wu C, He S, Liu J, Wang B, Lin J, Duan Y, et al. Type 1 innate lymphoid cell aggravation of atherosclerosis is mediated through TLR4. Scand J Immunol. 2018;87:e12661 pubmed publisher
Di Marco Barros R, Roberts N, Dart R, Vantourout P, Jandke A, Nussbaumer O, et al. Epithelia Use Butyrophilin-like Molecules to Shape Organ-Specific γδ T Cell Compartments. Cell. 2016;167:203-218.e17 pubmed publisher
Hu Z, Zhang W, Usherwood E. Regulatory CD8+ T cells associated with erosion of immune surveillance in persistent virus infection suppress in vitro and have a reversible proliferative defect. J Immunol. 2013;191:312-22 pubmed publisher
product information
Antigen :
CD122
Apps. Abbrev. :
FC
Cat # :
123210
Clone :
TM-β1
Item :
PE anti-mouse CD122 (IL-2Rβ)
Isotype :
Rat IgG2b, κ
Other Names :
IL-2 Receptor β chain, IL-2Rβ
Size :
100 μg
Price (USD) :
214 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
Rat T cell line expressing mouse CD122 ( IL-2Rβ)
Application Notes :
Additional reported applications (for the relevant formats) include: immunoprecipitation^1, blocking of IL-2 binding^1, and NK cell depletion^2 in vivo. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for blocking of IL-2 binding in vivo and in vitro (Cat. No. 123204).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA