product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Brilliant Violet 421™ anti-mouse F4/80
catalog :
123132
quantity :
500 μL
price :
360 USD
clonality :
monoclonal
host :
rat
conjugate :
BV421
clone name :
BM8
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 45
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 6s2
Canel M, Taggart D, Sims A, Lonergan D, Waizenegger I, Serrels A. T-cell co-stimulation in combination with targeting FAK drives enhanced anti-tumor immunity. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5
Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, et al. Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018;9:75 pubmed publisher
  • flow cytometry; mouse
Schulz C, Gomez Perdiguero E, Chorro L, Szabo Rogers H, Cagnard N, Kierdorf K, et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012;336:86-90 pubmed publisher
Brunner J, Vulliard L, Hofmann M, Kieler M, Lercher A, Vogel A, et al. Environmental arginine controls multinuclear giant cell metabolism and formation. Nat Commun. 2020;11:431 pubmed publisher
Reinhard K, Rengstl B, Oehm P, Michel K, Billmeier A, Hayduk N, et al. An RNA vaccine drives expansion and efficacy of claudin-CAR-T cells against solid tumors. Science. 2020;367:446-453 pubmed publisher
Wang X, Sun G, Feng T, Zhang J, Huang X, Wang T, et al. Sodium oligomannate therapeutically remodels gut microbiota and suppresses gut bacterial amino acids-shaped neuroinflammation to inhibit Alzheimer's disease progression. Cell Res. 2019;29:787-803 pubmed publisher
Kobayashi S, Sakurai T, So T, Shiota Y, Asao A, Phung H, et al. TNF Receptor-Associated Factor 5 Limits Function of Plasmacytoid Dendritic Cells by Controlling IFN Regulatory Factor 5 Expression. J Immunol. 2019;203:1447-1456 pubmed publisher
Lim J, Park H, Heisler J, Maculins T, Roose Girma M, Xu M, et al. Autophagy regulates inflammatory programmed cell death via turnover of RHIM-domain proteins. elife. 2019;8: pubmed publisher
He J, Song Y, Li G, Xiao P, Liu Y, Xue Y, et al. Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation. J Clin Invest. 2019;129:3877-3893 pubmed publisher
Merz S, Korste S, Bornemann L, Michel L, Stock P, Squire A, et al. Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response. Nat Commun. 2019;10:2312 pubmed publisher
Kurup S, Anthony S, Hancox L, Vijay R, Pewe L, Moioffer S, et al. Monocyte-Derived CD11c+ Cells Acquire Plasmodium from Hepatocytes to Prime CD8 T Cell Immunity to Liver-Stage Malaria. Cell Host Microbe. 2019;: pubmed publisher
Denny J, Powers J, Castro H, Zhang J, Joshi Barve S, Campagna S, et al. Differential Sensitivity to Plasmodium yoelii Infection in C57BL/6 Mice Impacts Gut-Liver Axis Homeostasis. Sci Rep. 2019;9:3472 pubmed publisher
Yu X, Chen L, Liu J, Dai B, Xu G, Shen G, et al. Immune modulation of liver sinusoidal endothelial cells by melittin nanoparticles suppresses liver metastasis. Nat Commun. 2019;10:574 pubmed publisher
Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, et al. Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis. Nat Microbiol. 2019;4:492-503 pubmed publisher
Chan W, Entwisle C, Ercoli G, Ramos Sevillano E, McIlgorm A, Cecchini P, et al. A Novel, Multiple-Antigen Pneumococcal Vaccine Protects against Lethal Streptococcus pneumoniae Challenge. Infect Immun. 2019;87: pubmed publisher
Tong Y, Zhou L, Yang L, Guo P, Cao Y, Qin F, et al. Concomitant type I IFN and M-CSF signaling reprograms monocyte differentiation and drives pro-tumoral arginase production. EBioMedicine. 2019;39:132-144 pubmed publisher
Heinen A, Nederlof R, Panjwani P, Spychala A, Tschaidse T, Reffelt H, et al. IGF1 Treatment Improves Cardiac Remodeling after Infarction by Targeting Myeloid Cells. Mol Ther. 2019;27:46-58 pubmed publisher
Säwén P, Eldeeb M, Erlandsson E, Kristiansen T, Laterza C, Kokaia Z, et al. Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging. elife. 2018;7: pubmed publisher
Kumar M, Du J, Lagoudas G, Jiao Y, Sawyer A, Drummond D, et al. Analysis of Single-Cell RNA-Seq Identifies Cell-Cell Communication Associated with Tumor Characteristics. Cell Rep. 2018;25:1458-1468.e4 pubmed publisher
Li Z, Liu S, Xu J, Zhang X, Han D, Liu J, et al. Adult Connective Tissue-Resident Mast Cells Originate from Late Erythro-Myeloid Progenitors. Immunity. 2018;49:640-653.e5 pubmed publisher
Sokol C, Camire R, Jones M, Luster A. The Chemokine Receptor CCR8 Promotes the Migration of Dendritic Cells into the Lymph Node Parenchyma to Initiate the Allergic Immune Response. Immunity. 2018;49:449-463.e6 pubmed publisher
Lyons J, Ghazi P, Starchenko A, Tovaglieri A, Baldwin K, Poulin E, et al. The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile. PLoS Biol. 2018;16:e2002417 pubmed publisher
Barbet G, Sander L, Geswell M, Leonardi I, Cerutti A, Iliev I, et al. Sensing Microbial Viability through Bacterial RNA Augments T Follicular Helper Cell and Antibody Responses. Immunity. 2018;48:584-598.e5 pubmed publisher
Lyons J, Brubaker D, Ghazi P, Baldwin K, Edwards A, Boukhali M, et al. Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis. Sci Signal. 2018;11: pubmed publisher
Mrdjen D, Pavlovic A, Hartmann F, Schreiner B, Utz S, Leung B, et al. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity. 2018;48:380-395.e6 pubmed publisher
Khare P, Challa D, Devanaboyina S, Velmurugan R, Hughes S, Greenberg B, et al. Myelin oligodendrocyte glycoprotein-specific antibodies from multiple sclerosis patients exacerbate disease in a humanized mouse model. J Autoimmun. 2018;86:104-115 pubmed publisher
Topper M, Vaz M, Chiappinelli K, Destefano Shields C, Niknafs N, Yen R, et al. Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer. Cell. 2017;171:1284-1300.e21 pubmed publisher
Clemente Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis. Immunity. 2017;47:974-989.e8 pubmed publisher
Yao W, Ba Q, Li X, Li H, Zhang S, Yuan Y, et al. A Natural CCR2 Antagonist Relieves Tumor-associated Macrophage-mediated Immunosuppression to Produce a Therapeutic Effect for Liver Cancer. EBioMedicine. 2017;22:58-67 pubmed publisher
Suzuki T, Gao J, Ishigaki Y, Kondo K, Sawada S, Izumi T, et al. ER Stress Protein CHOP Mediates Insulin Resistance by Modulating Adipose Tissue Macrophage Polarity. Cell Rep. 2017;18:2045-2057 pubmed publisher
Clement M, Marsden M, Stacey M, Abdul Karim J, Gimeno Brias S, Costa Bento D, et al. Cytomegalovirus-Specific IL-10-Producing CD4+ T Cells Are Governed by Type-I IFN-Induced IL-27 and Promote Virus Persistence. PLoS Pathog. 2016;12:e1006050 pubmed publisher
Sun K, Yajjala V, Bauer C, Talmon G, Fischer K, Kielian T, et al. Nox2-derived oxidative stress results in inefficacy of antibiotics against post-influenza S. aureus pneumonia. J Exp Med. 2016;213:1851-64 pubmed publisher
Crichton M, Muller D, Depelsenaire A, Pearson F, Wei J, Coffey J, et al. The changing shape of vaccination: improving immune responses through geometrical variations of a microdevice for immunization. Sci Rep. 2016;6:27217 pubmed publisher
Croasdell A, Lacy S, Thatcher T, Sime P, Phipps R. Resolvin D1 Dampens Pulmonary Inflammation and Promotes Clearance of Nontypeable Haemophilus influenzae. J Immunol. 2016;196:2742-52 pubmed publisher
Zahr A, Alcaide P, Yang J, Jones A, Gregory M, dela Paz N, et al. Endomucin prevents leukocyte-endothelial cell adhesion and has a critical role under resting and inflammatory conditions. Nat Commun. 2016;7:10363 pubmed publisher
Müller P, Kreuzaler M, Khan T, Thommen D, Martin K, Glatz K, et al. Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade. Sci Transl Med. 2015;7:315ra188 pubmed publisher
Karsten C, Laumonnier Y, Eurich B, Ender F, Bröker K, Roy S, et al. Monitoring and cell-specific deletion of C5aR1 using a novel floxed GFP-C5aR1 reporter knock-in mouse. J Immunol. 2015;194:1841-55 pubmed publisher
Textor A, Listopad J, Wührmann L, Perez C, Kruschinski A, Chmielewski M, et al. Efficacy of CAR T-cell therapy in large tumors relies upon stromal targeting by IFNγ. Cancer Res. 2014;74:6796-805 pubmed publisher
Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, et al. Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses. elife. 2014;3:e04177 pubmed publisher
Sasi S, Song J, Park D, Enderling H, McDonald J, Gee H, et al. TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. J Biol Chem. 2014;289:14178-93 pubmed publisher
Thakur V, Liang Y, Lingappan K, Jiang W, Wang L, Barrios R, et al. Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicol Lett. 2014;230:322-32 pubmed publisher
Zenker S, Panteleev Ivlev J, Wirtz S, Kishimoto T, Waldner M, Ksionda O, et al. A key regulatory role for Vav1 in controlling lipopolysaccharide endotoxemia via macrophage-derived IL-6. J Immunol. 2014;192:2830-2836 pubmed publisher
Glass A, Wolf B, Schneider K, Princiotta M, Taffet S. Connexin43 is dispensable for phagocytosis. J Immunol. 2013;190:4830-5 pubmed publisher
Poeckel D, Zemski Berry K, Murphy R, Funk C. Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice. J Biol Chem. 2009;284:21077-89 pubmed publisher
Kobayashi M, Yoshida T, Takeuchi D, Jones V, Shigematsu K, Herndon D, et al. Gr-1(+)CD11b(+) cells as an accelerator of sepsis stemming from Pseudomonas aeruginosa wound infection in thermally injured mice. J Leukoc Biol. 2008;83:1354-62 pubmed publisher
product information
Antigen :
F4/80
Apps. Abbrev. :
Flow Cytometry, IHC-F
Cat # :
123132
Clone :
BM8
Item :
Brilliant Violet 421™ anti-mouse F4/80
Isotype :
Rat IgG2a, κ
Other Names :
EMR1, Ly71
Size :
500 μL
Price (USD) :
360 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BV421
Immunogen :
Murine macrophages
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections 1,2 and formalin-fixed paraffin-embedded sections 6,7 , and Western blotting.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA