product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Biotin anti-mouse F4/80
catalog :
123106
quantity :
500 μg
price :
178 USD
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
BM8
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 52
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Onodera T, Kita S, Adachi Y, Moriyama S, Sato A, Nomura T, et al. A SARS-CoV-2 antibody broadly neutralizes SARS-related coronaviruses and variants by coordinated recognition of a virus-vulnerable site. Immunity. 2021;54:2385-2398.e10 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 4b
Petley E, Koay H, Henderson M, Sek K, Todd K, Keam S, et al. MAIT cells regulate NK cell-mediated tumor immunity. Nat Commun. 2021;12:4746 pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig s9h
Bielecki P, Riesenfeld S, Hütter J, Torlai Triglia E, Kowalczyk M, Ricardo Gonzalez R, et al. Skin-resident innate lymphoid cells converge on a pathogenic effector state. Nature. 2021;592:128-132 pubmed publisher
  • flow cytometry; mouse
Suah A, Tran D, Khiew S, Andrade M, Pollard J, Jain D, et al. Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice. J Clin Invest. 2021;131: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig s2f, s4a
Wuggenig P, Kaya B, Melhem H, Ayata C, Hruz P, Sayan A, et al. Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice. Commun Biol. 2020;3:130 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1
Tizian C, Lahmann A, Hölsken O, Cosovanu C, Kofoed Branzk M, Heinrich F, et al. c-Maf restrains T-bet-driven programming of CCR6-negative group 3 innate lymphoid cells. elife. 2020;9: pubmed publisher
  • immunohistochemistry - frozen section; mouse; loading ...; fig 2d
Oda A, Tezuka T, Ueno Y, Hosoda S, Amemiya Y, Notsu C, et al. Niche-induced extramedullary hematopoiesis in the spleen is regulated by the transcription factor Tlx1. Sci Rep. 2018;8:8308 pubmed publisher
  • flow cytometry; mouse; 1:500; loading ...; fig s4a
Yeh C, Nojima T, Kuraoka M, Kelsoe G. Germinal center entry not selection of B cells is controlled by peptide-MHCII complex density. Nat Commun. 2018;9:928 pubmed publisher
  • flow cytometry; mouse; fig 2d
Thion M, Low D, Silvin A, Chen J, Grisel P, Schulte Schrepping J, et al. Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner. Cell. 2018;172:500-516.e16 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:150; loading ...; fig 4h
Wang X, Chen H, Tian R, Zhang Y, Drutskaya M, Wang C, et al. Macrophages induce AKT/β-catenin-dependent Lgr5+ stem cell activation and hair follicle regeneration through TNF. Nat Commun. 2017;8:14091 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3c
Yanagita T, Murata Y, Tanaka D, Motegi S, Arai E, Daniwijaya E, et al. Anti-SIRPα antibodies as a potential new tool for cancer immunotherapy. JCI Insight. 2017;2:e89140 pubmed publisher
  • flow cytometry; mouse
Chen J, Miyanishi M, Wang S, Yamazaki S, Sinha R, Kao K, et al. Hoxb5 marks long-term haematopoietic stem cells and reveals a homogenous perivascular niche. Nature. 2016;530:223-7 pubmed publisher
  • flow cytometry; mouse
Schulz C, Gomez Perdiguero E, Chorro L, Szabo Rogers H, Cagnard N, Kierdorf K, et al. A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012;336:86-90 pubmed publisher
Kim A, Kim S, Leszczyńska A, Kaufmann B, Reca A, Kim D, et al. Dual role of neutrophils in modulating liver injury and fibrosis during development and resolution of diet-induced murine steatohepatitis. Sci Rep. 2021;11:24194 pubmed publisher
Liao Y, Wu S, Huang Y, Lo P, Chan T, Chen C, et al. NOX2-Deficient Neutrophils Facilitate Joint Inflammation Through Higher Pro-Inflammatory and Weakened Immune Checkpoint Activities. Front Immunol. 2021;12:743030 pubmed publisher
Iturri L, Freyer L, Biton A, Dardenne P, Lallemand Y, Gomez Perdiguero E. Megakaryocyte production is sustained by direct differentiation from erythromyeloid progenitors in the yolk sac until midgestation. Immunity. 2021;54:1433-1446.e5 pubmed publisher
Krueger P, Goldberg M, Hong S, Osum K, Langlois R, Kotov D, et al. Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells. Immunity. 2021;54:687-701.e4 pubmed publisher
Boccasavia V, Bovolenta E, Villanueva A, Borroto A, Oeste C, van Santen H, et al. Antigen presentation between T cells drives Th17 polarization under conditions of limiting antigen. Cell Rep. 2021;34:108861 pubmed publisher
Hazama D, Yin Y, Murata Y, Matsuda M, Okamoto T, Tanaka D, et al. Macrocyclic Peptide-Mediated Blockade of the CD47-SIRPα Interaction as a Potential Cancer Immunotherapy. Cell Chem Biol. 2020;27:1181-1191.e7 pubmed publisher
Bellomo A, Mondor I, Spinelli L, Lagueyrie M, Stewart B, Brouilly N, et al. Reticular Fibroblasts Expressing the Transcription Factor WT1 Define a Stromal Niche that Maintains and Replenishes Splenic Red Pulp Macrophages. Immunity. 2020;53:127-142.e7 pubmed publisher
Ruhland M, Roberts E, Cai E, Mujal A, Marchuk K, Beppler C, et al. Visualizing Synaptic Transfer of Tumor Antigens among Dendritic Cells. Cancer Cell. 2020;37:786-799.e5 pubmed publisher
Khiew S, Jain D, Chen J, Yang J, Yin D, Young J, et al. Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells. J Clin Invest. 2020;130:3453-3466 pubmed publisher
Crowe J, Lumb F, Doonan J, Broussard M, Tarafdar A, Pineda M, et al. The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing. PLoS Pathog. 2020;16:e1008391 pubmed publisher
Gordan S, Albert H, Danzer H, Lux A, Biburger M, Nimmerjahn F. The Immunological Organ Environment Dictates the Molecular and Cellular Pathways of Cytotoxic Antibody Activity. Cell Rep. 2019;29:3033-3046.e4 pubmed publisher
Onodera T, Hashi K, Shukla R, Miki M, Takai Todaka R, Fujimoto A, et al. Immune-Focusing Properties of Virus-like Particles Improve Protective IgA Responses. J Immunol. 2019;203:3282-3292 pubmed publisher
Akk A, Springer L, Yang L, Hamilton Burdess S, Lambris J, Yan H, et al. Complement activation on neutrophils initiates endothelial adhesion and extravasation. Mol Immunol. 2019;114:629-642 pubmed publisher
Adachi Y, Tonouchi K, Nithichanon A, Kuraoka M, Watanabe A, Shinnakasu R, et al. Exposure of an occluded hemagglutinin epitope drives selection of a class of cross-protective influenza antibodies. Nat Commun. 2019;10:3883 pubmed publisher
Calvente C, Tameda M, Johnson C, Del Pilar H, Lin Y, Adronikou N, et al. Neutrophils contribute to spontaneous resolution of liver inflammation and fibrosis via microRNA-223. J Clin Invest. 2019;129:4091-4109 pubmed publisher
Cianciaruso C, Beltraminelli T, Duval F, Nassiri S, Hamelin R, Mozes A, et al. Molecular Profiling and Functional Analysis of Macrophage-Derived Tumor Extracellular Vesicles. Cell Rep. 2019;27:3062-3080.e11 pubmed publisher
Cousin C, Oberkampf M, Félix T, Rosenbaum P, Weil R, Fabrega S, et al. Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses. Cell Rep. 2019;26:1242-1257.e7 pubmed publisher
Georgilis A, Klotz S, Hanley C, Herranz N, Weirich B, Morancho B, et al. PTBP1-Mediated Alternative Splicing Regulates the Inflammatory Secretome and the Pro-tumorigenic Effects of Senescent Cells. Cancer Cell. 2018;34:85-102.e9 pubmed publisher
Evrard M, Kwok I, Chong S, Teng K, Becht E, Chen J, et al. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity. 2018;48:364-379.e8 pubmed publisher
Moriyasu T, Nakamura R, Deloer S, Senba M, Kubo M, Inoue M, et al. Schistosoma mansoni infection suppresses the growth of Plasmodium yoelii parasites in the liver and reduces gametocyte infectivity to mosquitoes. PLoS Negl Trop Dis. 2018;12:e0006197 pubmed publisher
Linde N, Casanova Acebes M, Sosa M, Mortha A, Rahman A, Farias E, et al. Macrophages orchestrate breast cancer early dissemination and metastasis. Nat Commun. 2018;9:21 pubmed publisher
Joachim R, Suber F, Kobzik L. Characterising Pre-pubertal Resistance to Death from Endotoxemia. Sci Rep. 2017;7:16541 pubmed publisher
Grayczyk J, Harvey C, Laczkovich I, Alonzo F. A Lipoylated Metabolic Protein Released by Staphylococcus aureus Suppresses Macrophage Activation. Cell Host Microbe. 2017;22:678-687.e9 pubmed publisher
Yuan D, Huang S, Berger E, Liu L, Gross N, Heinzmann F, et al. Kupffer Cell-Derived Tnf Triggers Cholangiocellular Tumorigenesis through JNK due to Chronic Mitochondrial Dysfunction and ROS. Cancer Cell. 2017;31:771-789.e6 pubmed publisher
Miyauchi K, Sugimoto Ishige A, Harada Y, Adachi Y, Usami Y, Kaji T, et al. Protective neutralizing influenza antibody response in the absence of T follicular helper cells. Nat Immunol. 2016;17:1447-1458 pubmed publisher
Xu S, Wang X, Wang Y, Lutgendorf S, Bradley C, Schrepf A, et al. Transgenic Mice Expressing MCP-1 by the Urothelium Demonstrate Bladder Hypersensitivity, Pelvic Pain and Voiding Dysfunction: A Multidisciplinary Approach to the Study of Chronic Pelvic Pain Research Network Animal Model Study. PLoS ONE. 2016;11:e0163829 pubmed publisher
Wu W, Zhao L, Yang P, Zhou W, Li B, Moorhead J, et al. Inflammatory Stress Sensitizes the Liver to Atorvastatin-Induced Injury in ApoE-/- Mice. PLoS ONE. 2016;11:e0159512 pubmed publisher
Engels N, König L, Schulze W, Radtke D, Vanshylla K, Lutz J, et al. The immunoglobulin tail tyrosine motif upgrades memory-type BCRs by incorporating a Grb2-Btk signalling module. Nat Commun. 2014;5:5456 pubmed publisher
Chiba S, Ikushima H, Ueki H, Yanai H, Kimura Y, Hangai S, et al. Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses. elife. 2014;3:e04177 pubmed publisher
Knab L, Ebine K, Chow C, Raza S, Sahai V, Patel A, et al. Snail cooperates with Kras G12D in vivo to increase stem cell factor and enhance mast cell infiltration. Mol Cancer Res. 2014;12:1440-8 pubmed publisher
Sasi S, Song J, Park D, Enderling H, McDonald J, Gee H, et al. TNF-TNFR2/p75 signaling inhibits early and increases delayed nontargeted effects in bone marrow-derived endothelial progenitor cells. J Biol Chem. 2014;289:14178-93 pubmed publisher
Thakur V, Liang Y, Lingappan K, Jiang W, Wang L, Barrios R, et al. Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicol Lett. 2014;230:322-32 pubmed publisher
Sasaki O, Imamura M, Yamazumi Y, Harada H, Matsumoto T, Okunishi K, et al. Alendronate attenuates eosinophilic airway inflammation associated with suppression of Th2 cytokines, Th17 cytokines, and eotaxin-2. J Immunol. 2013;191:2879-89 pubmed publisher
Glass A, Wolf B, Schneider K, Princiotta M, Taffet S. Connexin43 is dispensable for phagocytosis. J Immunol. 2013;190:4830-5 pubmed publisher
Zoller E, Lykens J, Terrell C, Aliberti J, Filipovich A, Henson P, et al. Hemophagocytosis causes a consumptive anemia of inflammation. J Exp Med. 2011;208:1203-14 pubmed publisher
Yauch L, Prestwood T, May M, Morar M, Zellweger R, Peters B, et al. CD4+ T cells are not required for the induction of dengue virus-specific CD8+ T cell or antibody responses but contribute to protection after vaccination. J Immunol. 2010;185:5405-16 pubmed publisher
Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, et al. Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model. J Immunol. 2010;184:1543-51 pubmed publisher
Poeckel D, Zemski Berry K, Murphy R, Funk C. Dual 12/15- and 5-lipoxygenase deficiency in macrophages alters arachidonic acid metabolism and attenuates peritonitis and atherosclerosis in ApoE knock-out mice. J Biol Chem. 2009;284:21077-89 pubmed publisher
Kobayashi M, Yoshida T, Takeuchi D, Jones V, Shigematsu K, Herndon D, et al. Gr-1(+)CD11b(+) cells as an accelerator of sepsis stemming from Pseudomonas aeruginosa wound infection in thermally injured mice. J Leukoc Biol. 2008;83:1354-62 pubmed publisher
product information
Antigen :
F4/80
Apps. Abbrev. :
FC, IHC
Cat # :
123106
Clone :
BM8
Item :
Biotin anti-mouse F4/80
Isotype :
Rat IgG2a, κ
Other Names :
EMR1, Ly71
Size :
500 μg
Price (USD) :
178 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BIOTIN
Immunogen :
Murine macrophages
Application Notes :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections^1,2 and formalin-fixed paraffin-embedded sections^6,7, Western blotting, and spatial biology (IBEX)^12,13.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA