product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Pacific Blue™ anti-mouse Ly-6A/E (Sca-1)
catalog :
122519
quantity :
25 μg
price :
94 USD
clonality :
monoclonal
host :
rat
conjugate :
Pacific Blue
clone name :
E13-161.7
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 24
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig s3
Hu W, Dooley J, Chung S, Chandramohan D, Cimmino L, Mukherjee S, et al. miR-29a maintains mouse hematopoietic stem cell self-renewal by regulating Dnmt3a. Blood. 2015;125:2206-16 pubmed publisher
  • flow cytometry; mouse
CismaÅŸiu V, Popescu L. Telocytes transfer extracellular vesicles loaded with microRNAs to stem cells. J Cell Mol Med. 2015;19:351-8 pubmed publisher
Lawson H, van de Lagemaat L, Barile M, Tavosanis A, Durko J, Villacreces A, et al. CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation. Stem Cell Reports. 2021;16:2784-2797 pubmed publisher
Spevak C, Elias H, Kannan L, Ali M, Martin G, Selvaraj S, et al. Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms. Cell Stem Cell. 2020;26:755-765.e7 pubmed publisher
Nguyen D, Lu Y, Chu K, Yang X, Park S, Choo Z, et al. HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells. Nat Commun. 2020;11:2026 pubmed publisher
Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed publisher
Cheng Y, Luo H, Izzo F, Pickering B, Nguyen D, Myers R, et al. m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment. Cell Rep. 2019;28:1703-1716.e6 pubmed publisher
Paris J, Morgan M, Campos J, Spencer G, Shmakova A, Ivanova I, et al. Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. Cell Stem Cell. 2019;: pubmed publisher
Sala D, Cunningham T, Stec M, Etxaniz U, Nicoletti C, Dall Agnese A, et al. The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. Nat Commun. 2019;10:1796 pubmed publisher
Tzelepis K, De Braekeleer E, Aspris D, Barbieri I, Vijayabaskar M, Liu W, et al. SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4. Nat Commun. 2018;9:5378 pubmed publisher
Säwén P, Eldeeb M, Erlandsson E, Kristiansen T, Laterza C, Kokaia Z, et al. Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging. elife. 2018;7: pubmed publisher
Park S, Cho H, Thornton A, Barlowe T, Chou T, Chhangawala S, et al. IKZF2 Drives Leukemia Stem Cell Self-Renewal and Inhibits Myeloid Differentiation. Cell Stem Cell. 2019;24:153-165.e7 pubmed publisher
Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al. UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Nat Genet. 2018;50:883-894 pubmed publisher
Booth C, Barkas N, Neo W, Boukarabila H, Soilleux E, Giotopoulos G, et al. Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors. Cancer Cell. 2018;33:274-291.e8 pubmed publisher
Jee D, Yang J, Park S, Farmer D, Wen J, Chou T, et al. Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals. Mol Cell. 2018;69:265-278.e6 pubmed publisher
Courtney A, Amacher J, Kadlecek T, Mollenauer M, Au Yeung B, Kuriyan J, et al. A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45. Mol Cell. 2017;67:498-511.e6 pubmed publisher
Oben K, Gachuki B, Alhakeem S, McKenna M, Liang Y, St Clair D, et al. Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1). PLoS ONE. 2017;12:e0169767 pubmed publisher
Barrett N, Malouf C, Kapeni C, Bacon W, Giotopoulos G, Jacobsen S, et al. Mll-AF4 Confers Enhanced Self-Renewal and Lymphoid Potential during a Restricted Window in Development. Cell Rep. 2016;16:1039-1054 pubmed publisher
Wong J, Weinfurtner K, Alzamora M, Kogan S, Burgess M, Zhang Y, et al. Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. elife. 2015;4: pubmed publisher
Ellis S, Grassinger J, Jones A, Borg J, Camenisch T, Haylock D, et al. The relationship between bone, hemopoietic stem cells, and vasculature. Blood. 2011;118:1516-24 pubmed publisher
Rosas M, Thomas B, Stacey M, Gordon S, Taylor P. The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B. J Leukoc Biol. 2010;88:169-80 pubmed publisher
Felthaus O, Ernst W, Driemel O, Reichert T, Schmalz G, Morsczeck C. TGF-beta stimulates glial-like differentiation in murine dental follicle precursor cells (mDFPCs). Neurosci Lett. 2010;471:179-84 pubmed publisher
Fossati V, Kumar R, Snoeck H. Progenitor cell origin plays a role in fate choices of mature B cells. J Immunol. 2010;184:1251-60 pubmed publisher
Grassinger J, Haylock D, Storan M, Haines G, Williams B, Whitty G, et al. Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. Blood. 2009;114:49-59 pubmed publisher
product information
Antigen :
Ly-6A Ly-6E
Apps. Abbrev. :
Flow Cytometry
Cat # :
122519
Clone :
E13-161.7
Item :
Pacific Blue™ anti-mouse Ly-6A/E (Sca-1)
Isotype :
Rat IgG2a, κ
Other Names :
Sca-1
Size :
25 μg
Price (USD) :
94 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PB
Immunogen :
mouse pre-T cells
Application Notes :
Additional reported applications (for the relevant formats) include: complement-mediated cytoxicity 1 , immunohistochemical staining of frozen sections 2 and Bouin-fixed, paraffin-embedded samples 4 , immunofluorescence microscopy 4 , and immunoprecipitation 3 . The two Sca-1 recognizing clones D7 and E13-161.7 have been shown to bind distinct epitopes due to the inability of D7 to block the binding of E13-161.7. 7 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA