product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-mouse Ly-6A/E (Sca-1)
catalog :
122517
quantity :
25 μg
price :
94 USD
clonality :
monoclonal
host :
rat
conjugate :
AF647
clone name :
E13-161.7
reactivity :
mouse
application :
flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 21
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4d
Ray S, Chee L, Matson D, Palermo N, Bresnick E, Hewitt K. Sterile α-motif domain requirement for cellular signaling and survival. J Biol Chem. 2020;295:7113-7125 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig 2a
Nusse Y, Savage A, Marangoni P, Rosendahl Huber A, Landman T, De Sauvage F, et al. Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. Nature. 2018;559:109-113 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Umemoto T, Hashimoto M, Matsumura T, Nakamura Ishizu A, Suda T. Ca2+-mitochondria axis drives cell division in hematopoietic stem cells. J Exp Med. 2018;215:2097-2113 pubmed publisher
Kalafati L, Kourtzelis I, Schulte Schrepping J, Li X, Hatzioannou A, Grinenko T, et al. Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity. Cell. 2020;183:771-785.e12 pubmed publisher
Kobayashi H, Takubo K. Protocol for the Maintenance of Quiescent Murine Hematopoietic Stem Cells. STAR Protoc. 2020;1:100078 pubmed publisher
Sztwiertnia I, Schenz J, Bomans K, Schaack D, Ohnesorge J, Tamulyte S, et al. Sevoflurane depletes macrophages from the melanoma microenvironment. PLoS ONE. 2020;15:e0233789 pubmed publisher
Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, et al. Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. Nature. 2020;580:524-529 pubmed publisher
Nagai M, Noguchi R, Takahashi D, Morikawa T, Koshida K, Komiyama S, et al. Fasting-Refeeding Impacts Immune Cell Dynamics and Mucosal Immune Responses. Cell. 2019;178:1072-1087.e14 pubmed publisher
Zhu W, Naler L, Maul R, Sallin M, Sen J. Immune system development and age-dependent maintenance in Klotho-hypomorphic mice. Aging (Albany NY). 2019;11:5246-5257 pubmed publisher
Sala D, Cunningham T, Stec M, Etxaniz U, Nicoletti C, Dall Agnese A, et al. The Stat3-Fam3a axis promotes muscle stem cell myogenic lineage progression by inducing mitochondrial respiration. Nat Commun. 2019;10:1796 pubmed publisher
Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, et al. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. EMBO J. 2019;38: pubmed publisher
Rao T, Gupta M, Softic S, Wang L, Jang Y, Thomou T, et al. Attenuation of PKCδ enhances metabolic activity and promotes expansion of blood progenitors. EMBO J. 2018;37: pubmed publisher
Barth N, Marwick J, Heeb M, Gale A, Rossi A, Dransfield I. Augmentation of Human Monocyte Responses to Lipopolysaccharide by the Protein S and Mer/Tyro3 Receptor Tyrosine Kinase Axis. J Immunol. 2018;201:2602-2611 pubmed publisher
Verbiest T, Finnon R, Brown N, Cruz Garcia L, Finnon P, O Brien G, et al. Tracking preleukemic cells in vivo to reveal the sequence of molecular events in radiation leukemogenesis. Leukemia. 2018;32:1435-1444 pubmed publisher
Zhang H, Li H, Hillmer E, Zhao Y, Chrisikos T, Hu H, et al. Genetic rescue of lineage-balanced blood cell production reveals a crucial role for STAT3 antiinflammatory activity in hematopoiesis. Proc Natl Acad Sci U S A. 2018;115:E2311-E2319 pubmed publisher
Kollek M, Voigt G, Molnar C, Murad F, Bertele D, Krombholz C, et al. Transient apoptosis inhibition in donor stem cells improves hematopoietic stem cell transplantation. J Exp Med. 2017;214:2967-2983 pubmed publisher
Umemoto T, Matsuzaki Y, Shiratsuchi Y, Hashimoto M, Yoshimoto T, Nakamura Ishizu A, et al. Integrin αvβ3 enhances the suppressive effect of interferon-γ on hematopoietic stem cells. EMBO J. 2017;36:2390-2403 pubmed publisher
Ono R, Masuya M, Ishii S, Katayama N, Nosaka T. Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis. Mol Cell Biol. 2017;37: pubmed publisher
Cano E, Carmona R, Muñoz Chápuli R. Wt1-expressing progenitors contribute to multiple tissues in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2013;305:L322-32 pubmed publisher
Rosas M, Thomas B, Stacey M, Gordon S, Taylor P. The myeloid 7/4-antigen defines recently generated inflammatory macrophages and is synonymous with Ly-6B. J Leukoc Biol. 2010;88:169-80 pubmed publisher
Felthaus O, Ernst W, Driemel O, Reichert T, Schmalz G, Morsczeck C. TGF-beta stimulates glial-like differentiation in murine dental follicle precursor cells (mDFPCs). Neurosci Lett. 2010;471:179-84 pubmed publisher
product information
Antigen :
Ly-6A Ly-6E
Apps. Abbrev. :
Flow Cytometry
Cat # :
122517
Clone :
E13-161.7
Item :
Alexa Fluor® 647 anti-mouse Ly-6A/E (Sca-1)
Isotype :
Rat IgG2a, κ
Other Names :
Sca-1
Size :
25 μg
Price (USD) :
94 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A647
Immunogen :
mouse pre-T cells
Application Notes :
Additional reported applications (for the relevant formats) include: complement-mediated cytoxicity 1 , immunohistochemical staining of frozen sections 2 and Bouin-fixed, paraffin-embedded samples 4 , immunofluorescence microscopy 4 , and immunoprecipitation 3 . The two Sca-1 recognizing clones D7 and E13-161.7 have been shown to bind distinct epitopes due to the inability of D7 to block the binding of E13-161.7. 7
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA