PE/Cyanine7 anti-mouse CD28 | BioLegend 122014 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE/Cyanine7 anti-mouse CD28

catalog :

122014

quantity :

100 μg

price :

311 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

E18

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 5

Reference
Deak P, Studnitzer B, Ung T, Steinhardt R, Swartz M, Esser Kahn A. Isolating and targeting a highly active, stochastic dendritic cell subpopulation for improved immune responses. Cell Rep. 2022;41:111563 pubmed publisher
Zenke S, Sica M, Steinberg F, Braun J, Zink A, Gavrilov A, et al. Differential trafficking of ligands trogocytosed via CD28 versus CTLA4 promotes collective cellular control of co-stimulation. Nat Commun. 2022;13:6459 pubmed publisher
Sun Y, Xie J, Anyalebechi J, Chen C, Sun H, Xue M, et al. CD28 Agonism Improves Survival in Immunologically Experienced Septic Mice via IL-10 Released by Foxp3+ Regulatory T Cells. J Immunol. 2020;205:3358-3371 pubmed publisher
Köchl R, Vanes L, Llorian Sopena M, Chakravarty P, Hartweger H, Fountain K, et al. Critical role of WNK1 in MYC-dependent early mouse thymocyte development. elife. 2020;9: pubmed publisher
Espinosa J, Mou D, Adams B, Dibernardo L, MacDonald A, McRae M, et al. T Cell Repertoire Maturation Induced by Persistent and Latent Viral Infection Is Insufficient to Induce Costimulation Blockade Resistant Organ Allograft Rejection in Mice. Front Immunol. 2018;9:1371 pubmed publisher

product information

Antigen :

CD28

Apps. Abbrev. :

Cat # :

122014

Clone :

E18

Item :

PE/Cyanine7 anti-mouse CD28

Isotype :

Mouse IgG2b, κ

Other Names :

Tp44, T44

Size :

100 μg

Price (USD) :

311 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Mouse

Conjugate/Tag/Label :

PE_CYANINE7

Immunogen :

A20 cells and recombinant mCD28Ig

Application Notes :

Additional reported applications (for the relevant formats) include: in vitro costimulation of T and NK cells^1, in vitro blocking of allogeneic mixed leukocyte response and inhibition of MHC-unrestricted CTL cytotoxicity, and in vitro induction of thymocyte differentiation. The LEAF™ purified antibody (Endotoxin <0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. No. 122004).;

more info or order :

BioLegend product webpage