product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE anti-mouse CD107a (LAMP-1)
catalog :
121612
quantity :
200 μg
price :
292 USD
clonality :
monoclonal
host :
rat
conjugate :
PE
clone name :
1D4B
reactivity :
mouse
application :
immunohistochemistry, flow cytometry
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...
Chitirala P, Chang H, Martzloff P, Harenberg C, Ravichandran K, Abdulreda M, et al. Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2c
Dong M, Wang G, Chow R, Ye L, Zhu L, Dai X, et al. Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells. Cell. 2019;178:1189-1204.e23 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 3b
Niemann J, Woller N, Brooks J, Fleischmann Mundt B, Martin N, Kloos A, et al. Molecular retargeting of antibodies converts immune defense against oncolytic viruses into cancer immunotherapy. Nat Commun. 2019;10:3236 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5c
Ruscetti M, Leibold J, Bott M, Fennell M, Kulick A, Salgado N, et al. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018;362:1416-1422 pubmed publisher
  • flow cytometry; mouse; fig 1
Wang L, Ma N, Okamoto S, Amaishi Y, Sato E, Seo N, et al. Efficient tumor regression by adoptively transferred CEA-specific CAR-T cells associated with symptoms of mild cytokine release syndrome. Oncoimmunology. 2016;5:e1211218 pubmed
Afolabi L, Bi J, Li X, Adeshakin A, Adeshakin F, Wu H, et al. Synergistic Tumor Cytolysis by NK Cells in Combination With a Pan-HDAC Inhibitor, Panobinostat. Front Immunol. 2021;12:701671 pubmed publisher
Lu S, De Neef E, Thomas J, SABIO E, Rousseau B, Gigoux M, et al. Pharmacologic modulation of RNA splicing enhances anti-tumor immunity. Cell. 2021;184:4032-4047.e31 pubmed publisher
Sheppard S, Santosa E, Lau C, Violante S, Giovanelli P, Kim H, et al. Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function. Cell Rep. 2021;35:109210 pubmed publisher
Matsumoto M, Nakagawa S, Zhang L, Nakamura Y, Villaruz A, Otto M, et al. Interaction between Staphylococcus Agr virulence and neutrophils regulates pathogen expansion in the skin. Cell Host Microbe. 2021;29:930-940.e4 pubmed publisher
Wiedemann G, Grassmann S, Lau C, Rapp M, Villarino A, Friedrich C, et al. Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells. Cell Rep. 2020;33:108498 pubmed publisher
Utz B, Turpin R, Lampe J, Pouwels J, Klefstrom J. Assessment of the WAP-Myc mouse mammary tumor model for spontaneous metastasis. Sci Rep. 2020;10:18733 pubmed publisher
Díaz Salazar C, Sun J. Coordinated Viral Control by Cytotoxic Lymphocytes Ensures Optimal Adaptive NK Cell Responses. Cell Rep. 2020;32:108186 pubmed publisher
Blumenthal D, Chandra V, Avery L, Burkhardt J. Mouse T cell priming is enhanced by maturation-dependent stiffening of the dendritic cell cortex. elife. 2020;9: pubmed publisher
Geary C, Krishna C, Lau C, Adams N, Gearty S, Pritykin Y, et al. Non-redundant ISGF3 Components Promote NK Cell Survival in an Auto-regulatory Manner during Viral Infection. Cell Rep. 2018;24:1949-1957.e6 pubmed publisher
Adams N, Lau C, Fan X, Rapp M, Geary C, Weizman O, et al. Transcription Factor IRF8 Orchestrates the Adaptive Natural Killer Cell Response. Immunity. 2018;48:1172-1182.e6 pubmed publisher
Liu C, Min X, Wang N, Wang J, Ma N, Dong X, et al. Complement Receptor 3 Has Negative Impact on Tumor Surveillance through Suppression of Natural Killer Cell Function. Front Immunol. 2017;8:1602 pubmed publisher
Xu M, Pu Y, Han D, Shi Y, Cao X, Liang H, et al. Dendritic Cells but Not Macrophages Sense Tumor Mitochondrial DNA for Cross-priming through Signal Regulatory Protein ? Signaling. Immunity. 2017;47:363-373.e5 pubmed publisher
Hekim C, Ilander M, Yan J, Michaud E, Smykla R, Vähä Koskela M, et al. Dasatinib Changes Immune Cell Profiles Concomitant with Reduced Tumor Growth in Several Murine Solid Tumor Models. Cancer Immunol Res. 2017;5:157-169 pubmed publisher
Yang E, Singh B, Paustian A, Kambayashi T. Diacylglycerol Kinase ? Is a Target To Enhance NK Cell Function. J Immunol. 2016;197:934-41 pubmed publisher
Zhu M, Zou J, Li T, O Brien S, Zhang Y, Ogden S, et al. Differential Roles of Phospholipase D Proteins in FcεRI-Mediated Signaling and Mast Cell Function. J Immunol. 2015;195:4492-502 pubmed publisher
Holder K, Stapleton S, Gallant M, Russell R, Grant M. Hepatitis C virus-infected cells downregulate NKp30 and inhibit ex vivo NK cell functions. J Immunol. 2013;191:3308-18 pubmed publisher
del Rio M, Jones N, Buhler L, Norris P, Shintani Y, Ware C, et al. Selective blockade of herpesvirus entry mediator-B and T lymphocyte attenuator pathway ameliorates acute graft-versus-host reaction. J Immunol. 2012;188:4885-96 pubmed publisher
Difranco K, Gupta A, Galusha L, Perez J, Nguyen T, Fineza C, et al. Leukotoxin (Leukothera®) targets active leukocyte function antigen-1 (LFA-1) protein and triggers a lysosomal mediated cell death pathway. J Biol Chem. 2012;287:17618-27 pubmed publisher
product information
Antigen :
CD107a
Apps. Abbrev. :
Flow Cytometry
Cat # :
121612
Clone :
1D4B
Item :
PE anti-mouse CD107a (LAMP-1)
Isotype :
Rat IgG2a, κ
Other Names :
Lysosome-associated membrane glycoprotein 1, lysosomal membrane glycoprotein 1, CD107 antigen-like family member A, lysosome-associated membrane protein 1
Size :
200 μg
Price (USD) :
292 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE
Immunogen :
This monoclonal antibody was raised against NIH/3T3 mouse embryonic fibroblast tissue culture cell membranes. It has been mapped to the N-terminus of LAMP-1.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA