product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Alexa Fluor® 647 anti-mouse CD107a (LAMP-1)
catalog :
121610
quantity :
100 μg
price :
215 USD
clonality :
monoclonal
host :
rat
conjugate :
AF647
clone name :
1D4B
reactivity :
mouse
application :
immunohistochemistry, immunocytochemistry, flow cytometry, In-Cell Western
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:700; loading ...; fig 2e
Rizvi Z, Dalal R, Sadhu S, Kumar Y, Kumar S, Gupta S, et al. High-salt diet mediates interplay between NK cells and gut microbiota to induce potent tumor immunity. Sci Adv. 2021;7:eabg5016 pubmed publisher
  • immunohistochemistry; mouse; loading ...
Chitirala P, Chang H, Martzloff P, Harenberg C, Ravichandran K, Abdulreda M, et al. Studying the biology of cytotoxic T lymphocytes in vivo with a fluorescent granzyme B-mTFP knock-in mouse. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 1:200; loading ...; fig 3e
BURNS J, Cotleur B, Walther D, Bajrami B, Rubino S, Wei R, et al. Differential accumulation of storage bodies with aging defines discrete subsets of microglia in the healthy brain. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3
Zhao Y, Yang Q, Jin C, Feng Y, Xie S, Xie H, et al. Changes of CD103-expressing pulmonary CD4+ and CD8+ T cells in S. japonicum infected C57BL/6 mice. BMC Infect Dis. 2019;19:999 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2d
Li J, He Y, Hao J, Ni L, Dong C. High Levels of Eomes Promote Exhaustion of Anti-tumor CD8+ T Cells. Front Immunol. 2018;9:2981 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s5c
Ruscetti M, Leibold J, Bott M, Fennell M, Kulick A, Salgado N, et al. NK cell-mediated cytotoxicity contributes to tumor control by a cytostatic drug combination. Science. 2018;362:1416-1422 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3a
Muscate F, Stetter N, Schramm C, Schulze zur Wiesch J, Bosurgi L, Jacobs T. HVEM and CD160: Regulators of Immunopathology During Malaria Blood-Stage. Front Immunol. 2018;9:2611 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 2a
Ando T, Kashiwakura J, Itoh Nagato N, Yamashita H, Baba M, Kawakami Y, et al. Histamine-releasing factor enhances food allergy. J Clin Invest. 2017;127:4541-4553 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 5f
Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3f
Stacey M, Clare S, Clement M, Marsden M, Abdul Karim J, Kane L, et al. The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis. J Clin Invest. 2017;127:1463-1474 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s5a
Millrine D, Tei M, Gemechu Y, Kishimoto T. Rabex-5 is a lenalidomide target molecule that negatively regulates TLR-induced type 1 IFN production. Proc Natl Acad Sci U S A. 2016;113:10625-30 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 3h
Spiegel A, Brooks M, Houshyar S, Reinhardt F, Ardolino M, Fessler E, et al. Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells. Cancer Discov. 2016;6:630-49 pubmed publisher
  • In-Cell Western; mouse; fig s4
Alam S, Hennigar S, Gallagher C, Soybel D, Kelleher S. Exome Sequencing of SLC30A2 Identifies Novel Loss- and Gain-of-Function Variants Associated with Breast Cell Dysfunction. J Mammary Gland Biol Neoplasia. 2015;20:159-72 pubmed publisher
Spencer A, Morris S, Ulaszewska M, Powers C, Kailath R, Bissett C, et al. The ChAdOx1 vectored vaccine, AZD2816, induces strong immunogenicity against SARS-CoV-2 beta (B.1.351) and other variants of concern in preclinical studies. EBioMedicine. 2022;77:103902 pubmed publisher
Boulch M, Cazaux M, Loe Mie Y, Thibaut R, Corre B, Lemaitre F, et al. A cross-talk between CAR T cell subsets and the tumor microenvironment is essential for sustained cytotoxic activity. Sci Immunol. 2021;6: pubmed publisher
Laczkó D, Hogan M, Toulmin S, Hicks P, Lederer K, Gaudette B, et al. A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity. 2020;53:724-732.e7 pubmed publisher
van Doremalen N, Lambe T, Spencer A, Belij Rammerstorfer S, Purushotham J, Port J, et al. ChAdOx1 nCoV-19 vaccine prevents SARS-CoV-2 pneumonia in rhesus macaques. Nature. 2020;586:578-582 pubmed publisher
Rana A, de Almeida F, Paico Montero H, Gonzales Carazas M, Bortoluci K, Sad S, et al. RIPK3 and Caspase-1/11 Are Necessary for Optimal Antigen-Specific CD8 T Cell Response Elicited by Genetically Modified Listeria monocytogenes. Front Immunol. 2020;11:536 pubmed publisher
Pahari S, Negi S, Aqdas M, Arnett E, Schlesinger L, Agrewala J. Induction of autophagy through CLEC4E in combination with TLR4: an innovative strategy to restrict the survival of Mycobacterium tuberculosis. Autophagy. 2020;16:1021-1043 pubmed publisher
Engström P, Burke T, Mitchell G, Ingabire N, Mark K, Golovkine G, et al. Evasion of autophagy mediated by Rickettsia surface protein OmpB is critical for virulence. Nat Microbiol. 2019;4:2538-2551 pubmed publisher
Kurtulus S, Madi A, Escobar G, Klapholz M, Nyman J, Christian E, et al. Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T Cells. Immunity. 2019;50:181-194.e6 pubmed publisher
Uchil P, Pi R, Haugh K, Ladinsky M, Ventura J, Barrett B, et al. A Protective Role for the Lectin CD169/Siglec-1 against a Pathogenic Murine Retrovirus. Cell Host Microbe. 2019;25:87-100.e10 pubmed publisher
Marcus A, Mao A, Lensink Vasan M, Wang L, Vance R, Raulet D. Tumor-Derived cGAMP Triggers a STING-Mediated Interferon Response in Non-tumor Cells to Activate the NK Cell Response. Immunity. 2018;49:754-763.e4 pubmed publisher
Lin Z, Kuroki K, Kuse N, Sun X, Akahoshi T, Qi Y, et al. HIV-1 Control by NK Cells via Reduced Interaction between KIR2DL2 and HLA-C?12:02/C?14:03. Cell Rep. 2016;17:2210-2220 pubmed publisher
Mitchell G, Ge L, Huang Q, Chen C, Kianian S, Roberts M, et al. Avoidance of autophagy mediated by PlcA or ActA is required for Listeria monocytogenes growth in macrophages. Infect Immun. 2015;83:2175-84 pubmed publisher
Tran E, Chinnasamy D, Yu Z, Morgan R, Lee C, Restifo N, et al. Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia. J Exp Med. 2013;210:1125-35 pubmed publisher
Abiko K, Mandai M, Hamanishi J, Yoshioka Y, Matsumura N, Baba T, et al. PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. Clin Cancer Res. 2013;19:1363-74 pubmed publisher
van Montfoort N, Camps M, Khan S, Filippov D, Weterings J, Griffith J, et al. Antigen storage compartments in mature dendritic cells facilitate prolonged cytotoxic T lymphocyte cross-priming capacity. Proc Natl Acad Sci U S A. 2009;106:6730-5 pubmed publisher
product information
Antigen :
CD107a
Apps. Abbrev. :
Flow Cytometry
Cat # :
121610
Clone :
1D4B
Item :
Alexa Fluor® 647 anti-mouse CD107a (LAMP-1)
Isotype :
Rat IgG2a, κ
Other Names :
Lysosome-associated membrane glycoprotein 1, lysosomal membrane glycoprotein 1, CD107 antigen-like family member A, lysosome-associated membrane protein 1
Size :
100 μg
Price (USD) :
215 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
A647
Immunogen :
This monoclonal antibody was raised against NIH/3T3 mouse embryonic fibroblast tissue culture cell membranes. It has been mapped to the N-terminus of LAMP-1.
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA