This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
LEAF™ Purified anti-human/mouse integrin β7
catalog :
121003
quantity :
50 μg
price :
100 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
FIB27
reactivity :
human, mouse
application :
neutralization, immunoprecipitation, flow cytometry, blocking or activating experiments
citations: 12
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 4b
He S, Kahles F, Rattik S, Nairz M, McAlpine C, Anzai A, et al. Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease. Nature. 2019;566:115-119 pubmed publisher
  • blocking or activating experiments; human; fig 4b
  • flow cytometry; human; fig 1b
Buffone A, Anderson N, Hammer D. Migration against the direction of flow is LFA-1-dependent in human hematopoietic stem and progenitor cells. J Cell Sci. 2018;131: pubmed publisher
  • flow cytometry; human; 1:50; loading ...; fig 1
Briceno O, Pinto Cardoso S, Rodríguez Bernabe N, Murakami Ogasawara A, Reyes Teran G. Gut Homing CD4+ and CD8+ T-Cell Frequencies in HIV Infected Individuals on Antiretroviral Treatment. PLoS ONE. 2016;11:e0166496 pubmed publisher
  • blocking or activating experiments; mouse; fig 2b
Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
  • flow cytometry; human; fig 5
Termini C, Cotter M, Marjon K, Buranda T, Lidke K, Gillette J. The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density. Mol Biol Cell. 2014;25:1560-73 pubmed publisher
Allner C, Melde M, Becker E, Fuchs F, Mühl L, Klenske E, et al. Baseline levels of dynamic CD4+ T cell adhesion to MAdCAM-1 correlate with clinical response to vedolizumab treatment in ulcerative colitis: a cohort study. BMC Gastroenterol. 2020;20:103 pubmed publisher
Chng M, Lim M, Rouers A, Becht E, Lee B, Macary P, et al. Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates. Immunity. 2019;51:1119-1135.e5 pubmed publisher
Dzutsev A, Hogg A, Sui Y, Solaymani Mohammadi S, Yu H, Frey B, et al. Differential T cell homing to colon vs. small intestine is imprinted by local CD11c+ APCs that determine homing receptors. J Leukoc Biol. 2017;102:1381-1388 pubmed publisher
Kanemaru K, Noguchi E, Tokunaga T, Nagai K, Hiroyama T, Nakamura Y, et al. Tie2 Signaling Enhances Mast Cell Progenitor Adhesion to Vascular Cell Adhesion Molecule-1 (VCAM-1) through α4β1 Integrin. PLoS ONE. 2015;10:e0144436 pubmed publisher
Fischer A, Zundler S, Atreya R, Rath T, Voskens C, Hirschmann S, et al. Differential effects of α4β7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo. Gut. 2016;65:1642-64 pubmed publisher
Wiedemann T, Hofbaur S, Tegtmeyer N, Huber S, Sewald N, Wessler S, et al. Helicobacter pylori CagL dependent induction of gastrin expression via a novel ?v?5-integrin-integrin linked kinase signalling complex. Gut. 2012;61:986-96 pubmed publisher
Kohan M, Muro A, White E, Berkman N. EDA-containing cellular fibronectin induces fibroblast differentiation through binding to alpha4beta7 integrin receptor and MAPK/Erk 1/2-dependent signaling. FASEB J. 2010;24:4503-12 pubmed publisher
product information
Antigen :
Integrin beta7
Apps. Abbrev. :
Flow Cytometry, Block, IP
Cat # :
121003
Clone :
FIB27
Item :
LEAF™ Purified anti-human/mouse integrin β7
Isotype :
Rat IgG2a, κ
Other Names :
β7 Integrin, integrin βp, ITGB7
Size :
50 μg
Price (USD) :
100 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
LEAF
Immunogen :
TK1 cells
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA