product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Biotin anti-mouse/human PNAd
catalog :
120804
quantity :
500 μg
price :
282 USD
clonality :
monoclonal
host :
rat
conjugate :
biotin
clone name :
MECA-79
reactivity :
human, mouse
application :
immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 14
Reference
L xfc tge M, De Martin A, Gil Cruz C, Perez Shibayama C, Stanossek Y, Onder L, et al. Conserved stromal-immune cell circuits secure B cell homeostasis and function. Nat Immunol. 2023;24:1149-1160 pubmed publisher
Rodriguez A, Parriott G, Engelhard V. Tumor necrosis factor receptor regulation of peripheral node addressin biosynthetic components in tumor endothelial cells. Front Immunol. 2022;13:1009306 pubmed publisher
Rodriguez A, Peske J, Woods A, Leick K, Mauldin I, Meneveau M, et al. Immune mechanisms orchestrate tertiary lymphoid structures in tumors via cancer-associated fibroblasts. Cell Rep. 2021;36:109422 pubmed publisher
van Hooren L, Vaccaro A, Ramachandran M, Vazaios K, Libard S, van de Walle T, et al. Agonistic CD40 therapy induces tertiary lymphoid structures but impairs responses to checkpoint blockade in glioma. Nat Commun. 2021;12:4127 pubmed publisher
Xiong H, Mancini M, Gobert M, Shen S, Furtado G, Lira S, et al. Spleen plays a major role in DLL4-driven acute T-cell lymphoblastic leukemia. Theranostics. 2021;11:1594-1608 pubmed publisher
He W, Zhang D, Liu H, Chen T, Xie J, Peng L, et al. The High Level of Tertiary Lymphoid Structure Is Correlated With Superior Survival in Patients With Advanced Gastric Cancer. Front Oncol. 2020;10:980 pubmed publisher
Ligon M, Wang C, DeJong E, Schulz C, Bowdish D, Mysorekar I. Single cell and tissue-transcriptomic analysis of murine bladders reveals age- and TNFα-dependent but microbiota-independent tertiary lymphoid tissue formation. Mucosal Immunol. 2020;13:908-918 pubmed publisher
He W, Holtkamp S, Hergenhan S, Kraus K, De Juan A, Weber J, et al. Circadian Expression of Migratory Factors Establishes Lineage-Specific Signatures that Guide the Homing of Leukocyte Subsets to Tissues. Immunity. 2018;49:1175-1190.e7 pubmed publisher
Onder L, Mörbe U, Pikor N, Novković M, Cheng H, Hehlgans T, et al. Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis. Immunity. 2017;47:80-92.e4 pubmed publisher
Huppé C, Blais Lecours P, Lechasseur A, Gendron D, Lemay A, Bissonnette E, et al. A sphingosine-1-phosphate receptor 1 agonist inhibits tertiary lymphoid tissue reactivation and hypersensitivity in the lung. Mucosal Immunol. 2018;11:112-119 pubmed publisher
Yan X, Yan M, Guo Y, Singh G, Chen Y, Yu M, et al. R-Ras Regulates Murine T Cell Migration and Intercellular Adhesion Molecule-1 Binding. PLoS ONE. 2015;10:e0145218 pubmed publisher
Folgosa L, Zellner H, El Shikh M, Conrad D. Disturbed follicular architecture in B cell A disintegrin and metalloproteinase (ADAM)10 knockouts is mediated by compensatory increases in ADAM17 and TNF-? shedding. J Immunol. 2013;191:5951-8 pubmed publisher
Tsuboi K, Hirakawa J, Seki E, Imai Y, Yamaguchi Y, Fukuda M, et al. Role of high endothelial venule-expressed heparan sulfate in chemokine presentation and lymphocyte homing. J Immunol. 2013;191:448-55 pubmed publisher
Bombardieri M, Barone F, Lucchesi D, Nayar S, van den Berg W, Proctor G, et al. Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice. J Immunol. 2012;189:3767-76 pubmed
product information
Antigen :
PNAd
Apps. Abbrev. :
IHC-F, IHC-P
Cat # :
120804
Clone :
MECA-79
Item :
Biotin anti-mouse/human PNAd
Isotype :
Rat IgM, κ
Other Names :
PNAd, Peripheral Node Addressin, MECA-79
Size :
500 μg
Price (USD) :
282 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
BIOTIN
Immunogen :
Mouse lymph node stromal cells
Application Notes :
Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking^1-4 of cell adhesion, immunohistochemical staining^1,2,6 of acetone-fixed frozen sections and 4% paraformaldehyde-fixed paraffin-embedded sections, flow cytometry^10,11, immunoprecipitation^3,5, and Western blotting^6,11.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA