product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Purified anti-mouse/human PNAd
catalog :
120802
quantity :
500 μg
price :
262 USD
clonality :
monoclonal
host :
rat
conjugate :
nonconjugated
clone name :
MECA-79
reactivity :
human, mouse
application :
western blot, immunohistochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; loading ...; fig 1a
Peske J, Thompson E, Gemta L, Baylis R, Fu Y, Engelhard V. Effector lymphocyte-induced lymph node-like vasculature enables naive T-cell entry into tumours and enhanced anti-tumour immunity. Nat Commun. 2015;6:7114 pubmed publisher
  • immunohistochemistry - frozen section; human
Noort A, van Zoest K, van Baarsen L, Maracle C, Helder B, Papazian N, et al. Tertiary Lymphoid Structures in Rheumatoid Arthritis: NF-κB-Inducing Kinase-Positive Endothelial Cells as Central Players. Am J Pathol. 2015;185:1935-43 pubmed publisher
  • immunohistochemistry - frozen section; mouse; fig s5
Astarita J, Cremasco V, Fu J, Darnell M, Peck J, Nieves Bonilla J, et al. The CLEC-2-podoplanin axis controls the contractility of fibroblastic reticular cells and lymph node microarchitecture. Nat Immunol. 2015;16:75-84 pubmed publisher
  • immunohistochemistry; human; 1:25
Wirsing A, Rikardsen O, Steigen S, Uhlin Hansen L, Hadler Olsen E. Characterisation and prognostic value of tertiary lymphoid structures in oral squamous cell carcinoma. BMC Clin Pathol. 2014;14:38 pubmed publisher
Jiao S, Xiong Q, Yan M, Zhan X, Yang Z, Peng C, et al. Intratumor expanded T cell clones can be non-sentinel lymph node derived in breast cancer revealed by single-cell immune profiling. J Immunother Cancer. 2022;10: pubmed publisher
Li Q, Liu X, Wang D, Wang Y, Lu H, Wen S, et al. Prognostic value of tertiary lymphoid structure and tumour infiltrating lymphocytes in oral squamous cell carcinoma. Int J Oral Sci. 2020;12:24 pubmed publisher
Carlow D, Tra M, Ziltener H. A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin. PLoS ONE. 2018;13:e0205685 pubmed publisher
Yu S, Hsiao C, Izawa M, Yusa A, Ishida H, Nakamura S, et al. Distinct substrate specificities of human GlcNAc-6-sulfotransferases revealed by mass spectrometry-based sulfoglycomic analysis. J Biol Chem. 2018;293:15163-15177 pubmed publisher
Yang J, Cornelissen F, Papazian N, Reijmers R, Llorian M, Cupedo T, et al. IL-7-dependent maintenance of ILC3s is required for normal entry of lymphocytes into lymph nodes. J Exp Med. 2018;215:1069-1077 pubmed publisher
Kolachala V, Palle S, Shen M, Feng A, Shayakhmetov D, Gupta N. Loss of L-selectin-guided CD8+ , but not CD4+ , cells protects against ischemia reperfusion injury in a steatotic liver. Hepatology. 2017;66:1258-1274 pubmed publisher
Lynskey N, Banerji S, Johnson L, Holder K, Reglinski M, Wing P, et al. Rapid Lymphatic Dissemination of Encapsulated Group A Streptococci via Lymphatic Vessel Endothelial Receptor-1 Interaction. PLoS Pathog. 2015;11:e1005137 pubmed publisher
Thomas S, Rutkowski J, Pasquier M, Kuan E, Alitalo K, Randolph G, et al. Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage. J Immunol. 2012;189:2181-90 pubmed publisher
Hirakawa J, Tsuboi K, Sato K, Kobayashi M, Watanabe S, Takakura A, et al. Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing. J Biol Chem. 2010;285:40864-78 pubmed publisher
Burke S, Dong H, Hazan A, Croy B. Aberrant endometrial features of pregnancy in diabetic NOD mice. Diabetes. 2007;56:2919-26 pubmed
product information
Antigen :
PNAd
Apps. Abbrev. :
IHC-F, IHC-P, Flow Cytometry, IP, Western Blotting
Cat # :
120802
Clone :
MECA-79
Item :
Purified anti-mouse/human PNAd
Isotype :
Rat IgM, κ
Other Names :
PNAd, Peripheral Node Addressin, MECA-79
Size :
500 μg
Price (USD) :
262 USD
Reactivity :
Mouse, Human
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PURE
Immunogen :
Mouse lymph node stromal cells
Application Notes :
Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking 1-4 of cell adhesion, immunohistochemical staining 1,2,6 of acetone-fixed frozen sections and 4% paraformaldehyde-fixed paraffin-embedded sections, flow cytometry 10,11 , immunoprecipitation 3,5 , and Western blotting 6,11 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA