APC anti-mouse LPAM-1 (Integrin α4β7) | BioLegend 120608 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

APC anti-mouse LPAM-1 (Integrin α4β7)

catalog :

120608

quantity :

100 μg

price :

297 USD

clonality :

monoclonal

host :

rat

conjugate :

APC

clone name :

DATK32

reactivity :

mouse, rat

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 9

Reference
Behr F, Beumer Chuwonpad A, Kragten N, Wesselink T, Stark R, van Gisbergen K. Circulating memory CD8+ T cells are limited in forming CD103+ tissue-resident memory T cells at mucosal sites after reinfection. Eur J Immunol. 2021;51:151-166 pubmed publisher
Kitamoto S, Nagao Kitamoto H, Jiao Y, Gillilland M, Hayashi A, Imai J, et al. The Intermucosal Connection between the Mouth and Gut in Commensal Pathobiont-Driven Colitis. Cell. 2020;182:447-462.e14 pubmed publisher
Hurrell B, Galle Treger L, Jahani P, Howard E, Helou D, Banie H, et al. TNFR2 Signaling Enhances ILC2 Survival, Function, and Induction of Airway Hyperreactivity. Cell Rep. 2019;29:4509-4524.e5 pubmed publisher
Ghaedi M, Shen Z, Orangi M, Martínez González I, Wei L, Lu X, et al. Single-cell analysis of RORα tracer mouse lung reveals ILC progenitors and effector ILC2 subsets. J Exp Med. 2020;217: pubmed publisher
Calcinotto A, Brevi A, Chesi M, Ferrarese R, Garcia Perez L, Grioni M, et al. Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression. Nat Commun. 2018;9:4832 pubmed publisher
Knolle M, Chin S, Rana B, Englezakis A, Nakagawa R, Fallon P, et al. MicroRNA-155 Protects Group 2 Innate Lymphoid Cells From Apoptosis to Promote Type-2 Immunity. Front Immunol. 2018;9:2232 pubmed publisher
Kishore M, Cheung K, Fu H, Bonacina F, Wang G, Coe D, et al. Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis. Immunity. 2017;47:875-889.e10 pubmed publisher
Kawano H, Kayama H, Nakama T, Hashimoto T, Umemoto E, Takeda K. IL-10-producing lung interstitial macrophages prevent neutrophilic asthma. Int Immunol. 2016;28:489-501 pubmed
Tian Y, Cox M, Kahan S, Ingram J, Bakshi R, Zajac A. A Context-Dependent Role for IL-21 in Modulating the Differentiation, Distribution, and Abundance of Effector and Memory CD8 T Cell Subsets. J Immunol. 2016;196:2153-66 pubmed publisher

product information

Antigen :

LPAM-1

Apps. Abbrev. :

Cat # :

120608

Clone :

DATK32

Item :

APC anti-mouse LPAM-1 (Integrin α4β7)

Isotype :

Rat IgG2a, κ

Other Names :

α4β7 Integrin, CD49d/β7, LPAM-1, ITGA4, ITGB7

Size :

100 μg

Price (USD) :

297 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

APC

Immunogen :

TK1 cells

Application Notes :

Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of cell adhesion^1-4, in vitro induction of TK1 cell aggregation^1, immunoprecipitation^4, and immunohistochemical staining of frozen sections^5. It has been reported that the DATK32 mAb is able to block a4ß7 mediated lymphocyte adhesion to VCAM-1, MAdCAM-1, and fibronectin in vitro and in vivo.

more info or order :

BioLegend product webpage