PE anti-mouse LPAM-1 (Integrin α4β7) | BioLegend 120606 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

PE anti-mouse LPAM-1 (Integrin α4β7)

catalog :

120606

quantity :

200 μg

price :

297 USD

clonality :

monoclonal

host :

rat

conjugate :

clone name :

DATK32

reactivity :

mouse, rat

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 12

Reference
Zhang Z, Li J, Zhang M, Li B, Pan X, Dong X, et al. GPR109a Regulates Phenotypic and Functional Alterations in Macrophages and the Progression of Type 1 Diabetes. Mol Nutr Food Res. 2022;66:e2200300 pubmed publisher
Gary E, Tursi N, Warner B, Parzych E, Ali A, Frase D, et al. Mucosal chemokine adjuvant enhances synDNA vaccine-mediated responses to SARS-CoV-2 and provides heterologous protection in vivo. Cell Rep Med. 2022;3:100693 pubmed publisher
Nie J, Carpenter A, Chopp L, Chen T, Balmaceno Criss M, Ciucci T, et al. The transcription factor LRF promotes integrin β7 expression by and gut homing of CD8αα+ intraepithelial lymphocyte precursors. Nat Immunol. 2022;23:594-604 pubmed publisher
Peng C, Huggins M, Wanhainen K, Knutson T, Lu H, Georgiev H, et al. Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells. Immunity. 2021;: pubmed publisher
Shaikh H, Vargas J, Mokhtari Z, Jarick K, Ulbrich M, Mosca J, et al. Mesenteric Lymph Node Transplantation in Mice to Study Immune Responses of the Gastrointestinal Tract. Front Immunol. 2021;12:689896 pubmed publisher
Bennion B, Croft C, Ai T, Qian W, Menos A, Miner C, et al. STING Gain-of-Function Disrupts Lymph Node Organogenesis and Innate Lymphoid Cell Development in Mice. Cell Rep. 2020;31:107771 pubmed publisher
Duc D, Vigne S, Bernier Latmani J, Yersin Y, Ruiz F, Gaïa N, et al. Disrupting Myelin-Specific Th17 Cell Gut Homing Confers Protection in an Adoptive Transfer Experimental Autoimmune Encephalomyelitis. Cell Rep. 2019;29:378-390.e4 pubmed publisher
Nagatake T, Hirata S, Koga T, Kuroda E, Kobari S, Suzuki H, et al. BLT1 mediates commensal bacteria-dependent innate immune signals to enhance antigen-specific intestinal IgA responses. Mucosal Immunol. 2019;: pubmed publisher
Ise W, Fujii K, Shiroguchi K, Ito A, Kometani K, Takeda K, et al. T Follicular Helper Cell-Germinal Center B Cell Interaction Strength Regulates Entry into Plasma Cell or Recycling Germinal Center Cell Fate. Immunity. 2018;48:702-715.e4 pubmed publisher
Resch T, Wang Y, Moon S, Joyce J, Li S, PRAUSNITZ M, et al. Inactivated rotavirus vaccine by parenteral administration induces mucosal immunity in mice. Sci Rep. 2018;8:561 pubmed publisher
Woyciechowski S, Hofmann M, Pircher H. ?4 ?1 integrin promotes accumulation of tissue-resident memory CD8+ T cells in salivary glands. Eur J Immunol. 2017;47:244-250 pubmed publisher
Bemark M, Hazanov H, Strömberg A, Komban R, Holmqvist J, Köster S, et al. Limited clonal relatedness between gut IgA plasma cells and memory B cells after oral immunization. Nat Commun. 2016;7:12698 pubmed publisher

product information

Antigen :

LPAM-1

Apps. Abbrev. :

Cat # :

120606

Clone :

DATK32

Item :

PE anti-mouse LPAM-1 (Integrin α4β7)

Isotype :

Rat IgG2a, κ

Other Names :

α4β7 Integrin, CD49d/β7, LPAM-1, ITGA4, ITGB7

Size :

200 μg

Price (USD) :

297 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

Immunogen :

TK1 cells

Application Notes :

Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of cell adhesion^1-4, in vitro induction of TK1 cell aggregation^1, immunoprecipitation^4, and immunohistochemical staining of frozen sections^5. It has been reported that the DATK32 mAb is able to block a4ß7 mediated lymphocyte adhesion to VCAM-1, MAdCAM-1, and fibronectin in vitro and in vivo.

more info or order :

BioLegend product webpage