Purified anti-mouse LPAM-1 (Integrin α4β7) | BioLegend 120602 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Purified anti-mouse LPAM-1 (Integrin α4β7)

catalog :

120602

quantity :

500 μg

price :

258 USD

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

DATK32

reactivity :

mouse, rat

application :

neutralization, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

more info or order :

BioLegend product webpage

citations: 7

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; fig 2a	Yokota Nakatsuma A, Ohoka Y, Takeuchi H, Song S, Iwata M. Beta 1-integrin ligation and TLR ligation enhance GM-CSF-induced ALDH1A2 expression in dendritic cells, but differentially regulate their anti-inflammatory properties. Sci Rep. 2016;6:37914 pubmed publisher
flow cytometry; mouse; fig 7	Ushiki T, Huntington N, Glaser S, Kiu H, Georgiou A, Zhang J, et al. Rapid Inflammation in Mice Lacking Both SOCS1 and SOCS3 in Hematopoietic Cells. PLoS ONE. 2016;11:e0162111 pubmed publisher
	Sorini C, Cosorich I, Lo Conte M, De Giorgi L, Facciotti F, Lucianò R, et al. Loss of gut barrier integrity triggers activation of islet-reactive T cells and autoimmune diabetes. Proc Natl Acad Sci U S A. 2019;: pubmed publisher
	Scott N, Zhao Y, Krishnamurthy B, Mannering S, Kay T, Thomas H. IFNγ-Induced MHC Class II Expression on Islet Endothelial Cells Is an Early Marker of Insulitis but Is Not Required for Diabetogenic CD4+ T Cell Migration. Front Immunol. 2018;9:2800 pubmed publisher
	Elderman M, Hugenholtz F, Belzer C, Boekschoten M, van Beek A, de Haan B, et al. Sex and strain dependent differences in mucosal immunology and microbiota composition in mice. Biol Sex Differ. 2018;9:26 pubmed publisher
	Ju J, Jung M, Nam G, Kim W, Oh S, Kim H, et al. Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen. Nat Commun. 2018;9:225 pubmed publisher
	Toubai T, Rossi C, Oravecz Wilson K, Liu C, Zajac C, Wu S, et al. IAPs protect host target tissues from graft-versus-host disease in mice. Blood Adv. 2017;1:1517-1532 pubmed publisher

product information

Antigen :

LPAM-1

Apps. Abbrev. :

Flow Cytometry, Block, IP, IHC-F

Cat # :

120602

Clone :

DATK32

Item :

Purified anti-mouse LPAM-1 (Integrin α4β7)

Isotype :

Rat IgG2a, κ

Other Names :

α4β7 Integrin, CD49d/β7, LPAM-1, ITGA4, ITGB7

Size :

500 μg

Price (USD) :

258 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

PURE

Immunogen :

TK1 cells

Application Notes :

Additional reported applications (for the relevant formats) include: in vitro and in vivo blocking of cell adhesion 1-4 , in vitro induction of TK1 cell aggregation 1 , immunoprecipitation 4 , and immunohistochemical staining of frozen sections 5 . It has been reported that the DATK32 mAb is able to block a4ß7 mediated lymphocyte adhesion to VCAM-1, MAdCAM-1, and fibronectin in vitro and in vivo .

more info or order :

BioLegend product webpage