product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse CD197 (CCR7)
catalog :
120107
quantity :
25 μg
price :
119 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
4B12
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig s1f
Kishore M, Cheung K, Fu H, Bonacina F, Wang G, Coe D, et al. Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis. Immunity. 2017;47:875-889.e10 pubmed publisher
Wara A, Wang S, Wu C, Fang F, Haemmig S, Weber B, et al. KLF10 Deficiency in CD4+ T Cells Triggers Obesity, Insulin Resistance, and Fatty Liver. Cell Rep. 2020;33:108550 pubmed publisher
Sidwell T, Liao Y, Garnham A, Vasanthakumar A, Gloury R, Blume J, et al. Attenuation of TCR-induced transcription by Bach2 controls regulatory T cell differentiation and homeostasis. Nat Commun. 2020;11:252 pubmed publisher
Chng M, Lim M, Rouers A, Becht E, Lee B, Macary P, et al. Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates. Immunity. 2019;51:1119-1135.e5 pubmed publisher
Smith C, Chai S, Washington A, Lee S, Landoni E, Field K, et al. Machine-Learning Prediction of Tumor Antigen Immunogenicity in the Selection of Therapeutic Epitopes. Cancer Immunol Res. 2019;7:1591-1604 pubmed publisher
Liu J, Zhang X, Chen K, Cheng Y, Liu S, Xia M, et al. CCR7 Chemokine Receptor-Inducible lnc-Dpf3 Restrains Dendritic Cell Migration by Inhibiting HIF-1α-Mediated Glycolysis. Immunity. 2019;50:600-615.e15 pubmed publisher
Yu Y, Wang D, Li H, Liu Y, Xiang Z, Wu J, et al. IPSC‑MSC inhibition assessment in Raw 264.7 cells following oxygen and glucose deprivation reveals a distinct function for cardiopulmonary resuscitation. Mol Med Rep. 2018;17:8212-8220 pubmed publisher
Bantug G, Fischer M, Grählert J, Balmer M, Unterstab G, Develioglu L, et al. Mitochondria-Endoplasmic Reticulum Contact Sites Function as Immunometabolic Hubs that Orchestrate the Rapid Recall Response of Memory CD8+ T Cells. Immunity. 2018;48:542-555.e6 pubmed publisher
Han S, Glatman Zaretsky A, Andrade Oliveira V, Collins N, Dzutsev A, Shaik J, et al. White Adipose Tissue Is a Reservoir for Memory T Cells and Promotes Protective Memory Responses to Infection. Immunity. 2017;47:1154-1168.e6 pubmed publisher
Clemente Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis. Immunity. 2017;47:974-989.e8 pubmed publisher
Wang H, Akuthota P, Kanaoka Y, Weller P. Airway eosinophil migration into lymph nodes in mice depends on leukotriene C4. Allergy. 2017;72:927-936 pubmed publisher
Koyama M, Cheong M, Markey K, Gartlan K, Kuns R, Locke K, et al. Donor colonic CD103+ dendritic cells determine the severity of acute graft-versus-host disease. J Exp Med. 2015;212:1303-21 pubmed publisher
MacDonald K, Le Texier L, Zhang P, Morris H, Kuns R, Lineburg K, et al. Modification of T cell responses by stem cell mobilization requires direct signaling of the T cell by G-CSF and IL-10. J Immunol. 2014;192:3180-9 pubmed publisher
Wallner S, Lutz Nicoladoni C, Tripp C, Gastl G, Baier G, Penninger J, et al. The role of the e3 ligase cbl-B in murine dendritic cells. PLoS ONE. 2013;8:e65178 pubmed publisher
Kandasamy M, Ying P, Ho A, Sumatoh H, Schlitzer A, Hughes T, et al. Complement mediated signaling on pulmonary CD103(+) dendritic cells is critical for their migratory function in response to influenza infection. PLoS Pathog. 2013;9:e1003115 pubmed publisher
Inamine A, Sakurai D, Horiguchi S, Yonekura S, Hanazawa T, Hosokawa H, et al. Sublingual administration of Lactobacillus paracasei KW3110 inhibits Th2-dependent allergic responses via upregulation of PD-L2 on dendritic cells. Clin Immunol. 2012;143:170-9 pubmed publisher
del Rio M, Cote Sierra J, Rodriguez Barbosa J. Flt3L-mobilized dendritic cells bearing H2-Kbm1 apoptotic cells do not induce cross-tolerance to CD8+ T cells across a class I MHC mismatched barrier. Transpl Int. 2011;24:501-13 pubmed publisher
Bankoti J, Burnett A, Navarro S, Miller A, Rase B, Shepherd D. Effects of TCDD on the fate of naive dendritic cells. Toxicol Sci. 2010;115:422-34 pubmed publisher
Shimura E, Hozumi N, Kanagawa O, Metzger D, Chambon P, Radtke F, et al. Epidermal gammadelta T cells sense precancerous cellular dysregulation and initiate immune responses. Int Immunol. 2010;22:329-40 pubmed publisher
Flórido M, McColl S, Appelberg R. Delayed recruitment of lymphocytes into the lungs of CD30-deficient mice during aerogenic Mycobacterium avium infections. Immunobiology. 2009;214:643-52 pubmed publisher
Murphy B, Sundareshan V, Cory T, Hayes D, Anstead M, Feola D. Azithromycin alters macrophage phenotype. J Antimicrob Chemother. 2008;61:554-60 pubmed publisher
Kang S, Lim H, Andrisani O, Broxmeyer H, Kim C. Vitamin A metabolites induce gut-homing FoxP3+ regulatory T cells. J Immunol. 2007;179:3724-33 pubmed
Allende M, Zhou D, Kalkofen D, BenHamed S, Tuymetova G, Borowski C, et al. S1P1 receptor expression regulates emergence of NKT cells in peripheral tissues. FASEB J. 2008;22:307-15 pubmed
Hwang I, Park C, Kehrl J. Impaired trafficking of Gnai2+/- and Gnai2-/- T lymphocytes: implications for T cell movement within lymph nodes. J Immunol. 2007;179:439-48 pubmed
Kurooka M, Kaneda Y. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells. Cancer Res. 2007;67:227-36 pubmed
Lee J, Kang S, Kim C. FoxP3+ T cells undergo conventional first switch to lymphoid tissue homing receptors in thymus but accelerated second switch to nonlymphoid tissue homing receptors in secondary lymphoid tissues. J Immunol. 2007;178:301-11 pubmed
Mao A, Paharkova Vatchkova V, Hardy J, Miller M, Kovats S. Estrogen selectively promotes the differentiation of dendritic cells with characteristics of Langerhans cells. J Immunol. 2005;175:5146-51 pubmed
Chen H, Hou J, Jiang X, Ma S, Meng M, Wang B, et al. Response of memory CD8+ T cells to severe acute respiratory syndrome (SARS) coronavirus in recovered SARS patients and healthy individuals. J Immunol. 2005;175:591-8 pubmed
product information
Antigen :
CD197
Apps. Abbrev. :
Flow Cytometry
Cat # :
120107
Clone :
4B12
Item :
APC anti-mouse CD197 (CCR7)
Isotype :
Rat IgG2a, κ
Other Names :
C-C chemokine receptor type 7 (CCR7), MIP-3 beta receptor, EBV-induced G protein coupled receptor 1, EBI-1, CD197
Size :
25 μg
Price (USD) :
119 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
Mouse CCR7 transfected RBL-2H3 cells
Application Notes :
The 4B12 antibody does not inhibit binding of ligand to receptor. Additional reported applications (for the relevant formats) include: immunoprecipitation. To reduce non-specific binding to cells bearing Fc-receptors, pre-incubation of cells with anti-mouse CD16/CD32, clone 93 (Cat. No. 101301/101302) is recommended prior to immunofluorescent staining. Staining with clone 4B12 is recommended at 37°C (see supplemental data of PE staining at differing temperatures) .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA