Brilliant Violet 785™ anti-mouse CD366 (Tim-3) | BioLegend 119725 product information

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

Brilliant Violet 785™ anti-mouse CD366 (Tim-3)

catalog :

119725

quantity :

50 μg

price :

303 USD

clonality :

monoclonal

host :

rat

conjugate :

Brilliant Violet 785

clone name :

RMT3-23

reactivity :

mouse

application :

flow cytometry

more info or order :

BioLegend product webpage

citations: 7

Reference
van Elsas M, Labrie C, Etzerodt A, Charoentong P, van Stigt Thans J, van Hall T, et al. Invasive margin tissue-resident macrophages of high CD163 expression impede responses to T cell-based immunotherapy. J Immunother Cancer. 2023;11: pubmed publisher
Burger M, Cruz A, Crossland G, Gaglia G, Ritch C, Blatt S, et al. Antigen dominance hierarchies shape TCF1+ progenitor CD8 T cell phenotypes in tumors. Cell. 2021;184:4996-5014.e26 pubmed publisher
Schenkel J, Herbst R, Canner D, Li A, Hillman M, Shanahan S, et al. Conventional type I dendritic cells maintain a reservoir of proliferative tumor-antigen specific TCF-1+ CD8+ T cells in tumor-draining lymph nodes. Immunity. 2021;54:2338-2353.e6 pubmed publisher
Fedele C, Li S, Teng K, Foster C, Peng D, Ran H, et al. SHP2 inhibition diminishes KRASG12C cycling and promotes tumor microenvironment remodeling. J Exp Med. 2021;218: pubmed publisher
Liu H, Kuang X, Zhang Y, Ye Y, Li J, Liang L, et al. ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis. Cancer Cell. 2020;37:324-339.e8 pubmed publisher
Burrack A, Spartz E, Raynor J, Wang I, Olson M, Stromnes I. Combination PD-1 and PD-L1 Blockade Promotes Durable Neoantigen-Specific T Cell-Mediated Immunity in Pancreatic Ductal Adenocarcinoma. Cell Rep. 2019;28:2140-2155.e6 pubmed publisher
Chow M, Ozga A, Servis R, Frederick D, Lo J, Fisher D, et al. Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy. Immunity. 2019;: pubmed publisher

product information

Antigen :

CD366

Apps. Abbrev. :

Cat # :

119725

Clone :

RMT3-23

Item :

Brilliant Violet 785™ anti-mouse CD366 (Tim-3)

Isotype :

Rat IgG2a, κ

Other Names :

T cell immunoglobulin and mucin domain containing 3 protein, hepatitis virus cellular receptor 2, CD366

Size :

50 μg

Price (USD) :

303 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Rat

Conjugate/Tag/Label :

BV785

Application Notes :

Additional reported applications (for relevant formats) include: in vitro^1 and in vivo^2 blocking of Tim-3, and immunohistochemical staining of frozen sections^2. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 119731-119736).;

more info or order :

BioLegend product webpage