product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-mouse CD366 (Tim-3)
catalog :
119718
quantity :
100 μg
price :
382 USD
clonality :
monoclonal
host :
rat
conjugate :
PerCP/Cy5.5
clone name :
RMT3-23
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 14
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 2a
Que W, Ma K, Hu X, Guo W, Li X. Combinations of anti-GITR antibody and CD28 superagonist induce permanent allograft acceptance by generating type 1 regulatory T cells. Sci Adv. 2022;8:eabo4413 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s6f
Poggio M, Hu T, Pai C, Chu B, BELAIR C, Chang A, et al. Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. Cell. 2019;177:414-427.e13 pubmed publisher
Zeng S, Zhang Z, Ye C, Wang J, Jing C, Li L. Mediating immunosuppressive functions: a new perspective on the complex immunological properties of SEMA4D in the tumor microenvironment. Front Oncol. 2023;13:1171926 pubmed publisher
Battistello E, Hixon K, Comstock D, Collings C, Chen X, Rodriguez Hernaez J, et al. Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion. Mol Cell. 2023;83:1216-1236.e12 pubmed publisher
Scherer S, Oberle S, Kanev K, Gerullis A, Wu M, de Almeida G, et al. Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development. Nat Immunol. 2023;24:501-515 pubmed publisher
Zheng Y, Chen Z, Zhou B, Chen S, Han L, Chen N, et al. PRMT5 Deficiency Enforces the Transcriptional and Epigenetic Programs of Klrg1+CD8+ Terminal Effector T Cells and Promotes Cancer Development. J Immunol. 2022;208:501-513 pubmed publisher
Wang G, Xie L, Li B, Sang W, Yan J, Li J, et al. A nanounit strategy reverses immune suppression of exosomal PD-L1 and is associated with enhanced ferroptosis. Nat Commun. 2021;12:5733 pubmed publisher
Montalban Arques A, Katkeviciute E, Busenhart P, Bircher A, Wirbel J, Zeller G, et al. Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors. Cell Host Microbe. 2021;29:1573-1588.e7 pubmed publisher
Di Pilato M, Kfuri Rubens R, Pruessmann J, Ozga A, Messemaker M, Cadilha B, et al. CXCR6 positions cytotoxic T cells to receive critical survival signals in the tumor microenvironment. Cell. 2021;: pubmed publisher
Pu J, Xu Z, Nian J, Fang Q, Yang M, Huang Y, et al. M2 macrophage-derived extracellular vesicles facilitate CD8+T cell exhaustion in hepatocellular carcinoma via the miR-21-5p/YOD1/YAP/β-catenin pathway. Cell Death Discov. 2021;7:182 pubmed publisher
Dong L, Chen C, Zhang Y, Guo P, Wang Z, Li J, et al. The loss of RNA N6-adenosine methyltransferase Mettl14 in tumor-associated macrophages promotes CD8+ T cell dysfunction and tumor growth. Cancer Cell. 2021;39:945-957.e10 pubmed publisher
Cousin C, Oberkampf M, Félix T, Rosenbaum P, Weil R, Fabrega S, et al. Persistence of Integrase-Deficient Lentiviral Vectors Correlates with the Induction of STING-Independent CD8+ T Cell Responses. Cell Rep. 2019;26:1242-1257.e7 pubmed publisher
Tomaru U, Konno S, Miyajima S, Kimoto R, Onodera M, Kiuchi S, et al. Restricted Expression of the Thymoproteasome Is Required for Thymic Selection and Peripheral Homeostasis of CD8+ T Cells. Cell Rep. 2019;26:639-651.e2 pubmed publisher
Li J, Byrne K, Yan F, Yamazoe T, Chen Z, Baslan T, et al. Tumor Cell-Intrinsic Factors Underlie Heterogeneity of Immune Cell Infiltration and Response to Immunotherapy. Immunity. 2018;49:178-193.e7 pubmed publisher
product information
Antigen :
CD366
Apps. Abbrev. :
FC
Cat # :
119718
Clone :
RMT3-23
Item :
PerCP/Cyanine5.5 anti-mouse CD366 (Tim-3)
Isotype :
Rat IgG2a, κ
Other Names :
T cell immunoglobulin and mucin domain containing 3 protein, hepatitis virus cellular receptor 2, CD366
Size :
100 μg
Price (USD) :
382 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Application Notes :
Additional reported applications (for relevant formats) include: in vitro^1 and in vivo^2 blocking of Tim-3, and immunohistochemical staining of frozen sections^2. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 119731-119736).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA