product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PE/Cyanine7 anti-mouse CD366 (Tim-3)
catalog :
119716
quantity :
100 μg
price :
311 USD
clonality :
monoclonal
host :
rat
conjugate :
PE/Cy7
clone name :
RMT3-23
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 12
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; fig 4j
Böttcher J, Bonavita E, Chakravarty P, Blees H, Cabeza Cabrerizo M, Sammicheli S, et al. NK Cells Stimulate Recruitment of cDC1 into the Tumor Microenvironment Promoting Cancer Immune Control. Cell. 2018;172:1022-1037.e14 pubmed publisher
Morales Molina Á, Rodriguez Milla M, Gambera S, Cejalvo T, de Andr xe9 s B, Gaspar M, et al. Toll-like Receptor Signaling-deficient Cells Enhance Antitumor Activity of Cell-based Immunotherapy by Increasing Tumor Homing. Cancer Res Commun. 2023;3:347-360 pubmed publisher
Li X, Li Y, Dong L, Chang Y, Zhang X, Wang C, et al. Decitabine priming increases anti-PD-1 antitumor efficacy by promoting CD8+ progenitor exhausted T cell expansion in tumor models. J Clin Invest. 2023;133: pubmed publisher
Denk D, Petrocelli V, Conche C, Drachsler M, Ziegler P, Braun A, et al. Expansion of T memory stem cells with superior anti-tumor immunity by Urolithin A-induced mitophagy. Immunity. 2022;55:2059-2073.e8 pubmed publisher
Naranjo S, Cabana C, Lafave L, Romero R, Shanahan S, Bhutkar A, et al. Modeling diverse genetic subtypes of lung adenocarcinoma with a next-generation alveolar type 2 organoid platform. Genes Dev. 2022;36:936-949 pubmed publisher
Brog R, Ferry S, Schiebout C, Messier C, Cook W, Abdullah L, et al. Superkine IL2 and IL33 armored CAR T cells reshape the tumor microenvironment and reduce growth of multiple solid tumors. Cancer Immunol Res. 2022;: pubmed publisher
Zhang M, Zhou Q, Huang C, Chan C, Wu W, Li G, et al. In Vivo Evaluation of Near-Infrared Fluorescent Probe for TIM3 Targeting in Mouse Glioma. Mol Imaging Biol. 2022;24:280-287 pubmed publisher
Fitzgerald B, Connolly K, Cui C, Fagerberg E, Mariuzza D, Hornick N, et al. A mouse model for the study of anti-tumor T cell responses in Kras-driven lung adenocarcinoma. Cell Rep Methods. 2021;1: pubmed publisher
Olivo Pimentel V, Marcus D, van der Wiel A, Lieuwes N, Biemans R, Lieverse R, et al. Releasing the brakes of tumor immunity with anti-PD-L1 and pushing its accelerator with L19-IL2 cures poorly immunogenic tumors when combined with radiotherapy. J Immunother Cancer. 2021;9: pubmed publisher
Hegde S, Krisnawan V, Herzog B, Zuo C, Breden M, Knolhoff B, et al. Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer. Cancer Cell. 2020;37:289-307.e9 pubmed publisher
Yang B, Wang K, Wan S, Liang Y, Yuan X, Dong Y, et al. TCF1 and LEF1 Control Treg Competitive Survival and Tfr Development to Prevent Autoimmune Diseases. Cell Rep. 2019;27:3629-3645.e6 pubmed publisher
Cunha L, Yang M, Carter R, Guy C, Harris L, Crawford J, et al. LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance. Cell. 2018;175:429-441.e16 pubmed publisher
product information
Antigen :
CD366
Apps. Abbrev. :
FC
Cat # :
119716
Clone :
RMT3-23
Item :
PE/Cyanine7 anti-mouse CD366 (Tim-3)
Isotype :
Rat IgG2a, κ
Other Names :
T cell immunoglobulin and mucin domain containing 3 protein, hepatitis virus cellular receptor 2, CD366
Size :
100 μg
Price (USD) :
311 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
PE_CYANINE7
Application Notes :
Additional reported applications (for relevant formats) include: in vitro^1 and in vivo^2 blocking of Tim-3, and immunohistochemical staining of frozen sections^2. The Ultra-LEAF™ purified antibody (Endotoxin <0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for functional assays (Cat. Nos. 119731-119736).;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA