product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC/Cyanine7 anti-mouse CD326 (Ep-CAM)
catalog :
118218
quantity :
100 μg
price :
325 USD
clonality :
monoclonal
host :
rat
conjugate :
APC/Cy7
clone name :
G8.8
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 56
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...; fig 1s1a
Wells K, Miller C, Gschwind A, Wei W, Phipps J, Anderson M, et al. Combined transient ablation and single-cell RNA-sequencing reveals the development of medullary thymic epithelial cells. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1g, s1e
Ikonomou L, Herriges M, Lewandowski S, Marsland R, Villacorta Martin C, Caballero I, et al. The in vivo genetic program of murine primordial lung epithelial progenitors. Nat Commun. 2020;11:635 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2
Jürgensen H, Nørregaard K, Sibree M, Santoni Rugiu E, Madsen D, Wassilew K, et al. Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins. J Cell Biol. 2019;218:333-349 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 6b
Weeden C, Chen Y, Ma S, Hu Y, Ramm G, Sutherland K, et al. Lung Basal Stem Cells Rapidly Repair DNA Damage Using the Error-Prone Nonhomologous End-Joining Pathway. PLoS Biol. 2017;15:e2000731 pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 6a
Kechele D, Blue R, Zwarycz B, Espenschied S, Mah A, Siegel M, et al. Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation. J Clin Invest. 2017;127:593-607 pubmed publisher
  • flow cytometry; mouse; loading ...; fig s1a
Herzig Y, Nevo S, Bornstein C, Brezis M, Ben Hur S, Shkedy A, et al. Transcriptional programs that control expression of the autoimmune regulator gene Aire. Nat Immunol. 2017;18:161-172 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1b
Patenaude J, Perreault C. Thymic Mesenchymal Cells Have a Distinct Transcriptomic Profile. J Immunol. 2016;196:4760-70 pubmed publisher
  • flow cytometry; mouse; fig 1a
Tsukui T, Ueha S, Shichino S, Inagaki Y, Matsushima K. Intratracheal cell transfer demonstrates the profibrotic potential of resident fibroblasts in pulmonary fibrosis. Am J Pathol. 2015;185:2939-48 pubmed publisher
  • flow cytometry; mouse; fig 3
Chuprin A, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A, et al. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nat Immunol. 2015;16:737-45 pubmed publisher
  • flow cytometry; mouse; fig 3.26.3
Jain R, Gray D. Isolation of thymic epithelial cells and analysis by flow cytometry. Curr Protoc Immunol. 2014;107:3.26.1-15 pubmed publisher
  • flow cytometry; mouse
Makarem M, Kannan N, Nguyen L, Knapp D, Balani S, Prater M, et al. Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells. PLoS Biol. 2013;11:e1001630 pubmed publisher
Sakamoto K, Goel S, Funakoshi A, Honda T, Nagao K. Flow cytometry analysis of the subpopulations of mouse keratinocytes and skin immune cells. STAR Protoc. 2022;3:101052 pubmed publisher
Sefik E, Israelow B, Mirza H, Zhao J, Qu R, Kaffe E, et al. A humanized mouse model of chronic COVID-19. Nat Biotechnol. 2021;: pubmed publisher
Avgustinova A, Laudanna C, Pascual García M, Rovira Q, Djurec M, Castellanos A, et al. Repression of endogenous retroviruses prevents antiviral immune response and is required for mammary gland development. Cell Stem Cell. 2021;: pubmed publisher
Vercauteren Drubbel A, Pirard S, Kin S, Dassy B, Lefort A, Libert F, et al. Reactivation of the Hedgehog pathway in esophageal progenitors turns on an embryonic-like program to initiate columnar metaplasia. Cell Stem Cell. 2021;28:1411-1427.e7 pubmed publisher
Wirasinha R, Davies A, Srivastava M, Sheridan J, Sng X, Delmonte O, et al. Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility. J Exp Med. 2021;218: pubmed publisher
Lerbs T, Cui L, King M, Chai T, Muscat C, Chung L, et al. CD47 prevents the elimination of diseased fibroblasts in scleroderma. JCI Insight. 2020;5: pubmed publisher
Lebel M, Coutelier M, Galipeau M, Kleinman C, Moon J, Melichar H. Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates. Nat Commun. 2020;11:3734 pubmed publisher
Pauken K, Godec J, Odorizzi P, Brown K, Yates K, Ngiow S, et al. The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection. Cell Rep. 2020;31:107827 pubmed publisher
Pascual R, Martín J, Salvador F, Reina O, Chanes V, Millanes Romero A, et al. The RNA binding protein CPEB2 regulates hormone sensing in mammary gland development and luminal breast cancer. Sci Adv. 2020;6:eaax3868 pubmed publisher
Sfakianos J, Daza J, Hu Y, Anastos H, Bryant G, Bareja R, et al. Epithelial plasticity can generate multi-lineage phenotypes in human and murine bladder cancers. Nat Commun. 2020;11:2540 pubmed publisher
Morral C, Stanisavljevic J, Hernando Momblona X, Mereu E, Álvarez Varela A, Cortina C, et al. Zonation of Ribosomal DNA Transcription Defines a Stem Cell Hierarchy in Colorectal Cancer. Cell Stem Cell. 2020;26:845-861.e12 pubmed publisher
Romera Hernandez M, Aparicio Domingo P, Papazian N, Karrich J, Cornelissen F, Hoogenboezem R, et al. Yap1-Driven Intestinal Repair Is Controlled by Group 3 Innate Lymphoid Cells. Cell Rep. 2020;30:37-45.e3 pubmed publisher
Sitaraman S, Na C, Yang L, Filuta A, Bridges J, Weaver T. Proteasome dysfunction in alveolar type 2 epithelial cells is associated with acute respiratory distress syndrome. Sci Rep. 2019;9:12509 pubmed publisher
Crowell P, Fox J, Hashimoto T, Diaz J, Navarro H, Henry G, et al. Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate. Cell Rep. 2019;28:1499-1510.e6 pubmed publisher
Joshi P, Waterhouse P, Kasaian K, Fang H, Gulyaeva O, Sul H, et al. PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland. Nat Commun. 2019;10:1760 pubmed publisher
Moreau H, Blanch Mercader C, Attia R, Maurin M, Alraies Z, Sanséau D, et al. Macropinocytosis Overcomes Directional Bias in Dendritic Cells Due to Hydraulic Resistance and Facilitates Space Exploration. Dev Cell. 2019;: pubmed publisher
Zwarycz B, Gracz A, Rivera K, Williamson I, Samsa L, Starmer J, et al. IL22 Inhibits Epithelial Stem Cell Expansion in an Ileal Organoid Model. Cell Mol Gastroenterol Hepatol. 2019;7:1-17 pubmed publisher
Cohen M, Giladi A, Gorki A, Solodkin D, Zada M, Hladik A, et al. Lung Single-Cell Signaling Interaction Map Reveals Basophil Role in Macrophage Imprinting. Cell. 2018;175:1031-1044.e18 pubmed publisher
Thomson C, van de Pavert S, Stakenborg M, Labeeuw E, Matteoli G, Mowat A, et al. Expression of the Atypical Chemokine Receptor ACKR4 Identifies a Novel Population of Intestinal Submucosal Fibroblasts That Preferentially Expresses Endothelial Cell Regulators. J Immunol. 2018;201:215-229 pubmed publisher
O Reilly L, Putoczki T, Mielke L, Low J, Lin A, Preaudet A, et al. Loss of NF-κB1 Causes Gastric Cancer with Aberrant Inflammation and Expression of Immune Checkpoint Regulators in a STAT-1-Dependent Manner. Immunity. 2018;48:570-583.e8 pubmed publisher
Best S, De Souza D, Kersbergen A, Policheni A, Dayalan S, Tull D, et al. Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment. Cell Metab. 2018;27:935-943.e4 pubmed publisher
Bretou M, Sáez P, Sanséau D, Maurin M, Lankar D, Chabaud M, et al. Lysosome signaling controls the migration of dendritic cells. Sci Immunol. 2017;2: pubmed publisher
Lee S, Wilen C, Orvedahl A, McCune B, Kim K, Orchard R, et al. Norovirus Cell Tropism Is Determined by Combinatorial Action of a Viral Non-structural Protein and Host Cytokine. Cell Host Microbe. 2017;22:449-459.e4 pubmed publisher
Cai S, Kalisky T, Sahoo D, Dalerba P, Feng W, Lin Y, et al. A Quiescent Bcl11b High Stem Cell Population Is Required for Maintenance of the Mammary Gland. Cell Stem Cell. 2017;20:247-260.e5 pubmed publisher
El Agha E, Moiseenko A, Kheirollahi V, De Langhe S, Crnkovic S, Kwapiszewska G, et al. Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis. Cell Stem Cell. 2017;20:261-273.e3 pubmed publisher
Agarwal S, Hynes P, Tillman H, Lake R, Abou Kheir W, Fang L, et al. Identification of Different Classes of Luminal Progenitor Cells within Prostate Tumors. Cell Rep. 2015;13:2147-58 pubmed publisher
Ellis G, Davidson S, Crotta S, Branzk N, Papayannopoulos V, Wack A. TRAIL+ monocytes and monocyte-related cells cause lung damage and thereby increase susceptibility to influenza-Streptococcus pneumoniae coinfection. EMBO Rep. 2015;16:1203-18 pubmed publisher
Dumont Lagacé M, St Pierre C, Perreault C. Sex hormones have pervasive effects on thymic epithelial cells. Sci Rep. 2015;5:12895 pubmed publisher
St Pierre C, Trofimov A, Brochu S, Lemieux S, Perreault C. Differential Features of AIRE-Induced and AIRE-Independent Promiscuous Gene Expression in Thymic Epithelial Cells. J Immunol. 2015;195:498-506 pubmed publisher
Kim M, Miller C, Shadrach J, Wagers A, Serwold T. Young, proliferative thymic epithelial cells engraft and function in aging thymuses. J Immunol. 2015;194:4784-95 pubmed publisher
Ochiai S, Roediger B, Abtin A, Shklovskaya E, Fazekas de St Groth B, Yamane H, et al. CD326(lo)CD103(lo)CD11b(lo) dermal dendritic cells are activated by thymic stromal lymphopoietin during contact sensitization in mice. J Immunol. 2014;193:2504-11 pubmed publisher
Zaid A, Mackay L, Rahimpour A, Braun A, Veldhoen M, Carbone F, et al. Persistence of skin-resident memory T cells within an epidermal niche. Proc Natl Acad Sci U S A. 2014;111:5307-12 pubmed publisher
Hirokawa Y, Yip K, Tan C, Burgess A. Colonic myofibroblast cell line stimulates colonoid formation. Am J Physiol Gastrointest Liver Physiol. 2014;306:G547-56 pubmed publisher
Dumont Lagacé M, Brochu S, St Pierre C, Perreault C. Adult thymic epithelium contains nonsenescent label-retaining cells. J Immunol. 2014;192:2219-26 pubmed publisher
Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, et al. Nrf2 enhances cholangiocyte expansion in Pten-deficient livers. Mol Cell Biol. 2014;34:900-13 pubmed publisher
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed publisher
Garibaldi B, D Alessio F, Mock J, Files D, Chau E, Eto Y, et al. Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment. Am J Respir Cell Mol Biol. 2013;48:35-43 pubmed publisher
Manzo N, Foster W, Stripp B. Amphiregulin-dependent mucous cell metaplasia in a model of nonallergic lung injury. Am J Respir Cell Mol Biol. 2012;47:349-57 pubmed publisher
Ishii K, Kanatsu Shinohara M, Toyokuni S, Shinohara T. FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation. Development. 2012;139:1734-43 pubmed publisher
Takehashi M, Tada M, Kanatsu Shinohara M, Morimoto H, Kazuki Y, Oshimura M, et al. Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice. Biol Reprod. 2012;86:178 pubmed publisher
Morimoto H, Lee J, Tanaka T, Ishii K, Toyokuni S, Kanatsu Shinohara M, et al. In vitro transformation of mouse testis cells by oncogene transfection. Biol Reprod. 2012;86:148, 1-11 pubmed publisher
Mulholland D, Kobayashi N, Ruscetti M, Zhi A, Tran L, Huang J, et al. Pten loss and RAS/MAPK activation cooperate to promote EMT and metastasis initiated from prostate cancer stem/progenitor cells. Cancer Res. 2012;72:1878-89 pubmed publisher
Nudel I, Elnekave M, Furmanov K, Arizon M, Clausen B, Wilensky A, et al. Dendritic cells in distinct oral mucosal tissues engage different mechanisms to prime CD8+ T cells. J Immunol. 2011;186:891-900 pubmed publisher
Hinterberger M, Aichinger M, Prazeres da Costa O, Voehringer D, Hoffmann R, Klein L. Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance. Nat Immunol. 2010;11:512-9 pubmed publisher
Gracz A, Ramalingam S, Magness S. Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro. Am J Physiol Gastrointest Liver Physiol. 2010;298:G590-600 pubmed publisher
product information
Antigen :
CD326
Apps. Abbrev. :
Flow Cytometry
Cat # :
118218
Clone :
G8.8
Item :
APC/Cyanine7 anti-mouse CD326 (Ep-CAM)
Isotype :
Rat IgG2a, κ
Other Names :
CD326, EGP40, MIC18, TROP1, KSA
Size :
100 μg
Price (USD) :
325 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC_CYANINE7
Immunogen :
TE-71 thymic epithelial cell line
Application Notes :
Additional reported applications for clone G8.8 (for the relevant formats) include: immunohistochemistry of frozen sections: acetone fixed 1 , with or without OCT embedding 2,4 , and spatial biology (IBEX) 13,14 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA