product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse CD326 (Ep-CAM)
catalog :
118214
quantity :
100 μg
price :
250 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
G8.8
reactivity :
mouse
application :
immunohistochemistry, flow cytometry, immunohistochemistry - frozen section
more info or order :
citations: 42
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 2 ug/ml; loading ...; fig s9a, s25b, s25e
Wang J, Li P, Yu Y, Fu Y, Jiang H, Lu M, et al. Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science. 2020;367: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2s2c
Katsuda T, Matsuzaki J, Yamaguchi T, Yamada Y, Prieto Vila M, Hosaka K, et al. Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes. elife. 2019;8: pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:200; fig 1
Baptista M, Keszei M, Oliveira M, Sunahara K, Andersson J, Dahlberg C, et al. Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells. Nat Commun. 2016;7:12175 pubmed publisher
  • flow cytometry; mouse; fig 6
Perdigoto C, Dauber K, Bar C, Tsai P, Valdes V, Cohen I, et al. Polycomb-Mediated Repression and Sonic Hedgehog Signaling Interact to Regulate Merkel Cell Specification during Skin Development. PLoS Genet. 2016;12:e1006151 pubmed publisher
  • flow cytometry; mouse; 1:300
von Moltke J, Ji M, Liang H, Locksley R. Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit. Nature. 2016;529:221-5 pubmed publisher
  • flow cytometry; mouse; fig 1
Buerger S, Herrmann V, Mundt S, Trautwein N, Groettrup M, Basler M. The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection. J Immunol. 2015;195:4106-16 pubmed publisher
  • immunohistochemistry; mouse; 1:100
WANG Y, McAllister F, Bailey J, Scott S, Hendley A, Leach S, et al. Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia. PLoS ONE. 2014;9:e113127 pubmed publisher
  • flow cytometry; mouse
Cowan J, McCarthy N, Parnell S, White A, Bacon A, Serge A, et al. Differential requirement for CCR4 and CCR7 during the development of innate and adaptive ??T cells in the adult thymus. J Immunol. 2014;193:1204-12 pubmed publisher
  • flow cytometry; mouse
Makarem M, Kannan N, Nguyen L, Knapp D, Balani S, Prater M, et al. Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells. PLoS Biol. 2013;11:e1001630 pubmed publisher
Katara G, Kulshrestha A, Schneiderman S, Riehl V, Ibrahim S, Beaman K. Interleukin-22 promotes development of malignant lesions in a mouse model of spontaneous breast cancer. Mol Oncol. 2020;14:211-224 pubmed publisher
Santos C, Lapi E, Martínez de Villarreal J, Álvaro Espinosa L, Fernández Barral A, Barbachano A, et al. Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity. Nat Commun. 2019;10:4407 pubmed publisher
Kato T, Yasuda K, Matsushita K, Ishii K, Hirota S, Yoshimoto T, et al. Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis. Front Immunol. 2019;10:2021 pubmed publisher
Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed publisher
Komban R, Strömberg A, Biram A, Cervin J, Lebrero Fernández C, Mabbott N, et al. Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome. Nat Commun. 2019;10:2423 pubmed publisher
Pepe Mooney B, Dill M, Alemany A, Ordovas Montanes J, Matsushita Y, Rao A, et al. Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. Cell Stem Cell. 2019;: pubmed publisher
Finn J, Sottoriva K, Pajcini K, KITAJEWSKI J, Chen C, Zhang W, et al. Dlk1-Mediated Temporal Regulation of Notch Signaling Is Required for Differentiation of Alveolar Type II to Type I Cells during Repair. Cell Rep. 2019;26:2942-2954.e5 pubmed publisher
Castillo Azofeifa D, Fazio E, Nattiv R, Good H, Wald T, Pest M, et al. Atoh1+ secretory progenitors possess renewal capacity independent of Lgr5+ cells during colonic regeneration. EMBO J. 2019;38: pubmed publisher
Malik A, Sharma D, Malireddi R, Guy C, Chang T, Olsen S, et al. SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer. Immunity. 2018;49:515-530.e5 pubmed publisher
Guo X, Dash P, Crawford J, Allen E, Zamora A, Boyd D, et al. Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity. Immunity. 2018;49:531-544.e6 pubmed publisher
Smith N, Swain J, Davies P, Gallagher A, Parappilly M, Beach C, et al. Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations. Cell Mol Gastroenterol Hepatol. 2018;6:79-96 pubmed publisher
Tippimanchai D, Nolan K, Poczobutt J, Verzosa G, Li H, Scarborough H, et al. Adenoviral vectors transduce alveolar macrophages in lung cancer models. Oncoimmunology. 2018;7:e1438105 pubmed publisher
Cohen I, Zhao D, Bar C, Valdes V, Dauber Decker K, Nguyen M, et al. PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification. Cell Stem Cell. 2018;22:726-739.e7 pubmed publisher
Chua C, Epsi N, Leung E, Xuan S, Lei M, Li B, et al. Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation. elife. 2018;7: pubmed publisher
Renz B, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, et al. β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer. Cancer Cell. 2018;33:75-90.e7 pubmed publisher
Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
Malhotra D, Linehan J, Dileepan T, Lee Y, Purtha W, Lu J, et al. Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns. Nat Immunol. 2016;17:187-95 pubmed publisher
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, et al. RFX transcription factors are essential for hearing in mice. Nat Commun. 2015;6:8549 pubmed publisher
Barone F, Nayar S, Campos J, Cloake T, Withers D, Toellner K, et al. IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs. Proc Natl Acad Sci U S A. 2015;112:11024-9 pubmed publisher
Serra Hassoun M, Bourgine M, Boniotto M, Berges J, Langa F, Michel M, et al. Human hematopoietic reconstitution and HLA-restricted responses in nonpermissive alymphoid mice. J Immunol. 2014;193:1504-11 pubmed publisher
Tanimizu N, Nishikawa Y, Ichinohe N, Akiyama H, Mitaka T. Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes are involved in mouse liver regeneration. J Biol Chem. 2014;289:7589-98 pubmed publisher
Hirokawa Y, Yip K, Tan C, Burgess A. Colonic myofibroblast cell line stimulates colonoid formation. Am J Physiol Gastrointest Liver Physiol. 2014;306:G547-56 pubmed publisher
Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, et al. Nrf2 enhances cholangiocyte expansion in Pten-deficient livers. Mol Cell Biol. 2014;34:900-13 pubmed publisher
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed publisher
Casey O, Fang L, Hynes P, Abou Kheir W, Martin P, Tillman H, et al. TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation. PLoS ONE. 2012;7:e41668 pubmed publisher
King J, von Furstenberg R, Smith B, McNaughton K, Galanko J, Henning S. CD24 can be used to isolate Lgr5+ putative colonic epithelial stem cells in mice. Am J Physiol Gastrointest Liver Physiol. 2012;303:G443-52 pubmed publisher
Ishii K, Kanatsu Shinohara M, Toyokuni S, Shinohara T. FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation. Development. 2012;139:1734-43 pubmed publisher
Takehashi M, Tada M, Kanatsu Shinohara M, Morimoto H, Kazuki Y, Oshimura M, et al. Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice. Biol Reprod. 2012;86:178 pubmed publisher
Morimoto H, Lee J, Tanaka T, Ishii K, Toyokuni S, Kanatsu Shinohara M, et al. In vitro transformation of mouse testis cells by oncogene transfection. Biol Reprod. 2012;86:148, 1-11 pubmed publisher
Nudel I, Elnekave M, Furmanov K, Arizon M, Clausen B, Wilensky A, et al. Dendritic cells in distinct oral mucosal tissues engage different mechanisms to prime CD8+ T cells. J Immunol. 2011;186:891-900 pubmed publisher
Shultz L, Saito Y, Najima Y, Tanaka S, Ochi T, Tomizawa M, et al. Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice. Proc Natl Acad Sci U S A. 2010;107:13022-7 pubmed publisher
Hinterberger M, Aichinger M, Prazeres da Costa O, Voehringer D, Hoffmann R, Klein L. Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance. Nat Immunol. 2010;11:512-9 pubmed publisher
Gracz A, Ramalingam S, Magness S. Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro. Am J Physiol Gastrointest Liver Physiol. 2010;298:G590-600 pubmed publisher
product information
Antigen :
CD326
Apps. Abbrev. :
Flow Cytometry
Cat # :
118214
Clone :
G8.8
Item :
APC anti-mouse CD326 (Ep-CAM)
Isotype :
Rat IgG2a, κ
Other Names :
CD326, EGP40, MIC18, TROP1, KSA
Size :
100 μg
Price (USD) :
250 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
TE-71 thymic epithelial cell line
Application Notes :
Additional reported applications for clone G8.8 (for the relevant formats) include: immunohistochemistry of frozen sections: acetone fixed 1 , with or without OCT embedding 2,4 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA