product summary
Loading...
company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
APC anti-mouse CD326 (Ep-CAM)
catalog :
118213
quantity :
25 μg
price :
94 USD
clonality :
monoclonal
host :
rat
conjugate :
APC
clone name :
G8.8
reactivity :
mouse
application :
flow cytometry
more info or order :
citations: 68
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; 1:200; loading ...; fig 2b, 2c
Mevel R, Steiner I, Mason S, Galbraith L, Patel R, Fadlullah M, et al. RUNX1 marks a luminal castration-resistant lineage established at the onset of prostate development. elife. 2020;9: pubmed publisher
  • flow cytometry; mouse; 2 ug/ml; loading ...; fig s9a, s25b, s25e
Wang J, Li P, Yu Y, Fu Y, Jiang H, Lu M, et al. Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science. 2020;367: pubmed publisher
  • flow cytometry; mouse; 1:100; loading ...; fig 2s2c
Katsuda T, Matsuzaki J, Yamaguchi T, Yamada Y, Prieto Vila M, Hosaka K, et al. Generation of human hepatic progenitor cells with regenerative and metabolic capacities from primary hepatocytes. elife. 2019;8: pubmed publisher
  • flow cytometry; mouse; 1:300
von Moltke J, Ji M, Liang H, Locksley R. Tuft-cell-derived IL-25 regulates an intestinal ILC2-epithelial response circuit. Nature. 2016;529:221-5 pubmed publisher
  • flow cytometry; mouse; fig 1
Buerger S, Herrmann V, Mundt S, Trautwein N, Groettrup M, Basler M. The Ubiquitin-like Modifier FAT10 Is Selectively Expressed in Medullary Thymic Epithelial Cells and Modifies T Cell Selection. J Immunol. 2015;195:4106-16 pubmed publisher
  • flow cytometry; mouse; fig s4
Wu J, Okamura D, Li M, Suzuki K, Luo C, Ma L, et al. An alternative pluripotent state confers interspecies chimaeric competency. Nature. 2015;521:316-21 pubmed publisher
  • flow cytometry; mouse
Cowan J, McCarthy N, Parnell S, White A, Bacon A, Serge A, et al. Differential requirement for CCR4 and CCR7 during the development of innate and adaptive ??T cells in the adult thymus. J Immunol. 2014;193:1204-12 pubmed publisher
  • flow cytometry; mouse
Makarem M, Kannan N, Nguyen L, Knapp D, Balani S, Prater M, et al. Developmental changes in the in vitro activated regenerative activity of primitive mammary epithelial cells. PLoS Biol. 2013;11:e1001630 pubmed publisher
Lv X, Liu C, Liu S, Li Y, Wang W, Li K, et al. The cell cycle inhibitor P21 promotes the development of pulmonary fibrosis by suppressing lung alveolar regeneration. Acta Pharm Sin B. 2022;12:735-746 pubmed publisher
Rudnick J, Monkkonen T, Mar F, Barnes J, Starobinets H, Goldsmith J, et al. Autophagy in stromal fibroblasts promotes tumor desmoplasia and mammary tumorigenesis. Genes Dev. 2021;35:963-975 pubmed publisher
Jiang M, Fang Y, Li Y, Huang H, Wei Z, Gao X, et al. VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway. Dev Cell. 2021;56:1646-1660.e5 pubmed publisher
Willobee B, Gaidarski A, Dosch A, Castellanos J, Dai X, Mehra S, et al. Combined Blockade of MEK and CDK4/6 Pathways Induces Senescence to Improve Survival in Pancreatic Ductal Adenocarcinoma. Mol Cancer Ther. 2021;20:1246-1256 pubmed publisher
Chetty A, Darby M, Vornewald P, Martín Alonso M, Filz A, Ritter M, et al. Il4ra-independent vaginal eosinophil accumulation following helminth infection exacerbates epithelial ulcerative pathology of HSV-2 infection. Cell Host Microbe. 2021;29:579-593.e5 pubmed publisher
Ludwik K, Sandusky Z, Wright E, Lannigan D. FACS protocol for direct comparison of cell populations isolated from mice. STAR Protoc. 2021;2:100270 pubmed publisher
Chen Z, Luo J, Li J, Kim G, Stewart A, Urban J, et al. Interleukin-33 Promotes Serotonin Release from Enterochromaffin Cells for Intestinal Homeostasis. Immunity. 2021;54:151-163.e6 pubmed publisher
Ognjenovic N, Bagheri M, Mohamed G, Xu K, Chen Y, Mohamed Saleem M, et al. Limiting Self-Renewal of the Basal Compartment by PKA Activation Induces Differentiation and Alters the Evolution of Mammary Tumors. Dev Cell. 2020;55:544-557.e6 pubmed publisher
Boyd D, Allen E, Randolph A, Guo X, Weng Y, Sanders C, et al. Exuberant fibroblast activity compromises lung function via ADAMTS4. Nature. 2020;587:466-471 pubmed publisher
Paris A, Hayer K, Oved J, Avgousti D, Toulmin S, Zepp J, et al. STAT3-BDNF-TrkB signalling promotes alveolar epithelial regeneration after lung injury. Nat Cell Biol. 2020;22:1197-1210 pubmed publisher
Cheung P, Xiol J, Dill M, Yuan W, Panero R, Roper J, et al. Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer. Cell Stem Cell. 2020;27:590-604.e9 pubmed publisher
Chen Q, Rehman J, Chan M, Fu P, Dudek S, Natarajan V, et al. Angiocrine Sphingosine-1-Phosphate Activation of S1PR2-YAP Signaling Axis in Alveolar Type II Cells Is Essential for Lung Repair. Cell Rep. 2020;31:107828 pubmed publisher
Christin J, Wang C, Chung C, Liu Y, Dravis C, Tang W, et al. Stem Cell Determinant SOX9 Promotes Lineage Plasticity and Progression in Basal-like Breast Cancer. Cell Rep. 2020;31:107742 pubmed publisher
Bowling S, Sritharan D, Osorio F, Nguyen M, Cheung P, Rodriguez Fraticelli A, et al. An Engineered CRISPR-Cas9 Mouse Line for Simultaneous Readout of Lineage Histories and Gene Expression Profiles in Single Cells. Cell. 2020;181:1410-1422.e27 pubmed publisher
McGinty J, Ting H, Billipp T, Nadjsombati M, Khan D, Barrett N, et al. Tuft-Cell-Derived Leukotrienes Drive Rapid Anti-helminth Immunity in the Small Intestine but Are Dispensable for Anti-protist Immunity. Immunity. 2020;52:528-541.e7 pubmed publisher
Phung H, Nagashima H, Kobayashi S, Asano N, Machiyama T, Sakurai T, et al. TRAF5 Deficiency Ameliorates the Severity of Dextran Sulfate Sodium Colitis by Decreasing TRAF2 Expression in Nonhematopoietic Cells. Immunohorizons. 2020;4:129-139 pubmed publisher
Lai N, Musser M, Pinho Ribeiro F, Baral P, Jacobson A, Ma P, et al. Gut-Innervating Nociceptor Neurons Regulate Peyer's Patch Microfold Cells and SFB Levels to Mediate Salmonella Host Defense. Cell. 2020;180:33-49.e22 pubmed publisher
Katara G, Kulshrestha A, Schneiderman S, Riehl V, Ibrahim S, Beaman K. Interleukin-22 promotes development of malignant lesions in a mouse model of spontaneous breast cancer. Mol Oncol. 2020;14:211-224 pubmed publisher
Liu S, Rezende R, Moreira T, Tankou S, Cox L, Wu M, et al. Oral Administration of miR-30d from Feces of MS Patients Suppresses MS-like Symptoms in Mice by Expanding Akkermansia muciniphila. Cell Host Microbe. 2019;26:779-794.e8 pubmed publisher
Han H, Jain A, Truica M, Izquierdo Ferrer J, Anker J, Lysy B, et al. Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. Cancer Cell. 2019;36:483-497.e15 pubmed publisher
Santos C, Lapi E, Martínez de Villarreal J, Álvaro Espinosa L, Fernández Barral A, Barbachano A, et al. Urothelial organoids originating from Cd49fhigh mouse stem cells display Notch-dependent differentiation capacity. Nat Commun. 2019;10:4407 pubmed publisher
Kato T, Yasuda K, Matsushita K, Ishii K, Hirota S, Yoshimoto T, et al. Interleukin-1/-33 Signaling Pathways as Therapeutic Targets for Endometriosis. Front Immunol. 2019;10:2021 pubmed publisher
Gross K, Zhou W, Breindel J, Ouyang J, Jin D, Sokol E, et al. Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium. Cell Rep. 2019;28:394-407.e6 pubmed publisher
Bar C, Cohen I, Zhao D, Pothula V, Litskevitch A, Koseki H, et al. Polycomb Repressive Complex 1 Controls Maintenance of Fungiform Papillae by Repressing Sonic Hedgehog Expression. Cell Rep. 2019;28:257-266.e5 pubmed publisher
Sateriale A, Slapeta J, Baptista R, Engiles J, Gullicksrud J, Herbert G, et al. A Genetically Tractable, Natural Mouse Model of Cryptosporidiosis Offers Insights into Host Protective Immunity. Cell Host Microbe. 2019;: pubmed publisher
Komban R, Strömberg A, Biram A, Cervin J, Lebrero Fernández C, Mabbott N, et al. Activated Peyer's patch B cells sample antigen directly from M cells in the subepithelial dome. Nat Commun. 2019;10:2423 pubmed publisher
Pepe Mooney B, Dill M, Alemany A, Ordovas Montanes J, Matsushita Y, Rao A, et al. Single-Cell Analysis of the Liver Epithelium Reveals Dynamic Heterogeneity and an Essential Role for YAP in Homeostasis and Regeneration. Cell Stem Cell. 2019;: pubmed publisher
Jadhav U, Cavazza A, Banerjee K, Xie H, O Neill N, Saenz Vash V, et al. Extensive Recovery of Embryonic Enhancer and Gene Memory Stored in Hypomethylated Enhancer DNA. Mol Cell. 2019;74:542-554.e5 pubmed publisher
Finn J, Sottoriva K, Pajcini K, KITAJEWSKI J, Chen C, Zhang W, et al. Dlk1-Mediated Temporal Regulation of Notch Signaling Is Required for Differentiation of Alveolar Type II to Type I Cells during Repair. Cell Rep. 2019;26:2942-2954.e5 pubmed publisher
Yoshida H, Lareau C, Ramirez R, Rose S, Maier B, Wroblewska A, et al. The cis-Regulatory Atlas of the Mouse Immune System. Cell. 2019;176:897-912.e20 pubmed publisher
Castillo Azofeifa D, Fazio E, Nattiv R, Good H, Wald T, Pest M, et al. Atoh1+ secretory progenitors possess renewal capacity independent of Lgr5+ cells during colonic regeneration. EMBO J. 2019;38: pubmed publisher
Malik A, Sharma D, Malireddi R, Guy C, Chang T, Olsen S, et al. SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer. Immunity. 2018;49:515-530.e5 pubmed publisher
Guo X, Dash P, Crawford J, Allen E, Zamora A, Boyd D, et al. Lung γδ T Cells Mediate Protective Responses during Neonatal Influenza Infection that Are Associated with Type 2 Immunity. Immunity. 2018;49:531-544.e6 pubmed publisher
Smith N, Swain J, Davies P, Gallagher A, Parappilly M, Beach C, et al. Monoclonal Antibodies Reveal Dynamic Plasticity Between Lgr5- and Bmi1-Expressing Intestinal Cell Populations. Cell Mol Gastroenterol Hepatol. 2018;6:79-96 pubmed publisher
Tippimanchai D, Nolan K, Poczobutt J, Verzosa G, Li H, Scarborough H, et al. Adenoviral vectors transduce alveolar macrophages in lung cancer models. Oncoimmunology. 2018;7:e1438105 pubmed publisher
Cohen I, Zhao D, Bar C, Valdes V, Dauber Decker K, Nguyen M, et al. PRC1 Fine-tunes Gene Repression and Activation to Safeguard Skin Development and Stem Cell Specification. Cell Stem Cell. 2018;22:726-739.e7 pubmed publisher
Chua C, Epsi N, Leung E, Xuan S, Lei M, Li B, et al. Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation. elife. 2018;7: pubmed publisher
Renz B, Takahashi R, Tanaka T, Macchini M, Hayakawa Y, Dantes Z, et al. β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer. Cancer Cell. 2018;33:75-90.e7 pubmed publisher
Chamberlin T, D Amato J, Arendt L. Obesity reversibly depletes the basal cell population and enhances mammary epithelial cell estrogen receptor alpha expression and progenitor activity. Breast Cancer Res. 2017;19:128 pubmed publisher
Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
Baptista M, Keszei M, Oliveira M, Sunahara K, Andersson J, Dahlberg C, et al. Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells. Nat Commun. 2016;7:12175 pubmed publisher
Malhotra D, Linehan J, Dileepan T, Lee Y, Purtha W, Lu J, et al. Tolerance is established in polyclonal CD4(+) T cells by distinct mechanisms, according to self-peptide expression patterns. Nat Immunol. 2016;17:187-95 pubmed publisher
Elkon R, Milon B, Morrison L, Shah M, Vijayakumar S, Racherla M, et al. RFX transcription factors are essential for hearing in mice. Nat Commun. 2015;6:8549 pubmed publisher
Wei T, Zhang N, Guo Z, Chi F, Song Y, Zhu X. Wnt4 signaling is associated with the decrease of proliferation and increase of apoptosis during age-related thymic involution. Mol Med Rep. 2015;12:7568-76 pubmed publisher
Barone F, Nayar S, Campos J, Cloake T, Withers D, Toellner K, et al. IL-22 regulates lymphoid chemokine production and assembly of tertiary lymphoid organs. Proc Natl Acad Sci U S A. 2015;112:11024-9 pubmed publisher
WANG Y, McAllister F, Bailey J, Scott S, Hendley A, Leach S, et al. Dicer is required for maintenance of adult pancreatic acinar cell identity and plays a role in Kras-driven pancreatic neoplasia. PLoS ONE. 2014;9:e113127 pubmed publisher
Serra Hassoun M, Bourgine M, Boniotto M, Berges J, Langa F, Michel M, et al. Human hematopoietic reconstitution and HLA-restricted responses in nonpermissive alymphoid mice. J Immunol. 2014;193:1504-11 pubmed publisher
Tanimizu N, Nishikawa Y, Ichinohe N, Akiyama H, Mitaka T. Sry HMG box protein 9-positive (Sox9+) epithelial cell adhesion molecule-negative (EpCAM-) biphenotypic cells derived from hepatocytes are involved in mouse liver regeneration. J Biol Chem. 2014;289:7589-98 pubmed publisher
Hirokawa Y, Yip K, Tan C, Burgess A. Colonic myofibroblast cell line stimulates colonoid formation. Am J Physiol Gastrointest Liver Physiol. 2014;306:G547-56 pubmed publisher
Taguchi K, Hirano I, Itoh T, Tanaka M, Miyajima A, Suzuki A, et al. Nrf2 enhances cholangiocyte expansion in Pten-deficient livers. Mol Cell Biol. 2014;34:900-13 pubmed publisher
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed publisher
Casey O, Fang L, Hynes P, Abou Kheir W, Martin P, Tillman H, et al. TMPRSS2- driven ERG expression in vivo increases self-renewal and maintains expression in a castration resistant subpopulation. PLoS ONE. 2012;7:e41668 pubmed publisher
King J, von Furstenberg R, Smith B, McNaughton K, Galanko J, Henning S. CD24 can be used to isolate Lgr5+ putative colonic epithelial stem cells in mice. Am J Physiol Gastrointest Liver Physiol. 2012;303:G443-52 pubmed publisher
Ishii K, Kanatsu Shinohara M, Toyokuni S, Shinohara T. FGF2 mediates mouse spermatogonial stem cell self-renewal via upregulation of Etv5 and Bcl6b through MAP2K1 activation. Development. 2012;139:1734-43 pubmed publisher
Takehashi M, Tada M, Kanatsu Shinohara M, Morimoto H, Kazuki Y, Oshimura M, et al. Hybridization of testis-derived stem cells with somatic cells and embryonic stem cells in mice. Biol Reprod. 2012;86:178 pubmed publisher
Morimoto H, Lee J, Tanaka T, Ishii K, Toyokuni S, Kanatsu Shinohara M, et al. In vitro transformation of mouse testis cells by oncogene transfection. Biol Reprod. 2012;86:148, 1-11 pubmed publisher
Nudel I, Elnekave M, Furmanov K, Arizon M, Clausen B, Wilensky A, et al. Dendritic cells in distinct oral mucosal tissues engage different mechanisms to prime CD8+ T cells. J Immunol. 2011;186:891-900 pubmed publisher
Shultz L, Saito Y, Najima Y, Tanaka S, Ochi T, Tomizawa M, et al. Generation of functional human T-cell subsets with HLA-restricted immune responses in HLA class I expressing NOD/SCID/IL2r gamma(null) humanized mice. Proc Natl Acad Sci U S A. 2010;107:13022-7 pubmed publisher
Hinterberger M, Aichinger M, Prazeres da Costa O, Voehringer D, Hoffmann R, Klein L. Autonomous role of medullary thymic epithelial cells in central CD4(+) T cell tolerance. Nat Immunol. 2010;11:512-9 pubmed publisher
Gracz A, Ramalingam S, Magness S. Sox9 expression marks a subset of CD24-expressing small intestine epithelial stem cells that form organoids in vitro. Am J Physiol Gastrointest Liver Physiol. 2010;298:G590-600 pubmed publisher
product information
Antigen :
CD326
Apps. Abbrev. :
Flow Cytometry
Cat # :
118213
Clone :
G8.8
Item :
APC anti-mouse CD326 (Ep-CAM)
Isotype :
Rat IgG2a, κ
Other Names :
CD326, EGP40, MIC18, TROP1, KSA
Size :
25 μg
Price (USD) :
94 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Rat
Conjugate/Tag/Label :
APC
Immunogen :
TE-71 thymic epithelial cell line
Application Notes :
Additional reported applications for clone G8.8 (for the relevant formats) include: immunohistochemistry of frozen sections: acetone fixed 1 , with or without OCT embedding 2,4 , and spatial biology (IBEX) 13,14 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA