product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
PerCP/Cyanine5.5 anti-mouse TCR γ/δ
catalog :
118118
quantity :
100 μg
price :
323 USD
clonality :
monoclonal
host :
hamsters
conjugate :
PerCP/Cy5.5
clone name :
GL3
reactivity :
mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 29
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse; loading ...
Gangoso E, Southgate B, Bradley L, Rus S, Gálvez Cancino F, McGivern N, et al. Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion. Cell. 2021;184:2454-2470.e26 pubmed publisher
  • flow cytometry; mouse; 1:80; loading ...
Borges P, Waclawiak I, Georgii J, Fraga Junior V, Barros J, Lemos F, et al. Adenosine Diphosphate Improves Wound Healing in Diabetic Mice Through P2Y12 Receptor Activation. Front Immunol. 2021;12:651740 pubmed publisher
  • flow cytometry; mouse; loading ...; fig 1a
Moodley D, Yoshida H, Mostafavi S, Asinovski N, Ortiz Lopez A, Symanowicz P, et al. Network pharmacology of JAK inhibitors. Proc Natl Acad Sci U S A. 2016;113:9852-7 pubmed publisher
  • flow cytometry; mouse; fig 1, 2
Kim J, Choi Y, Lee B, Song M, Ban C, Kim J, et al. Programmed cell death ligand 1 alleviates psoriatic inflammation by suppressing IL-17A production from programmed cell death 1-high T cells. J Allergy Clin Immunol. 2016;137:1466-1476.e3 pubmed publisher
  • immunocytochemistry; mouse
Strid J, Sobolev O, Zafirova B, Polic B, Hayday A. The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy. Science. 2011;334:1293-7 pubmed publisher
Bajana S, Pankow A, Liu K, Michniowska M, Urban J, Chen W, et al. Correlation between circulating innate lymphoid cell precursors and thymic function. iScience. 2022;25:103732 pubmed publisher
Moudra A, Niederlova V, Novotny J, Schmiedová L, Kubovčiak J, Matejkova T, et al. Phenotypic and Clonal Stability of Antigen-Inexperienced Memory-like T Cells across the Genetic Background, Hygienic Status, and Aging. J Immunol. 2021;206:2109-2121 pubmed publisher
Wang G, Sweren E, Liu H, Wier E, Alphonse M, Chen R, et al. Bacteria induce skin regeneration via IL-1β signaling. Cell Host Microbe. 2021;29:777-791.e6 pubmed publisher
He Y, Fu L, Li Y, Wang W, Gong M, Zhang J, et al. Gut microbial metabolites facilitate anticancer therapy efficacy by modulating cytotoxic CD8+ T cell immunity. Cell Metab. 2021;33:988-1000.e7 pubmed publisher
Mikami Y, Philips R, Sciumè G, Petermann F, Meylan F, Nagashima H, et al. MicroRNA-221 and -222 modulate intestinal inflammatory Th17 cell response as negative feedback regulators downstream of interleukin-23. Immunity. 2021;54:514-525.e6 pubmed publisher
Sanchez Felipe L, Vercruysse T, Sharma S, Ma J, Lemmens V, Van Looveren D, et al. A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate. Nature. 2021;590:320-325 pubmed publisher
Iwanami N, Takeshita K, Lawir D, Suetake I, Tajima S, Sikora K, et al. Epigenetic Protection of Vertebrate Lymphoid Progenitor Cells by Dnmt1. iScience. 2020;23:101260 pubmed publisher
Siamishi I, Iwanami N, Clapes T, Trompouki E, O Meara C, Boehm T. Lymphocyte-Specific Function of the DNA Polymerase Epsilon Subunit Pole3 Revealed by Neomorphic Alleles. Cell Rep. 2020;31:107756 pubmed publisher
Cibrian D, Castillo González R, Fernández Gallego N, de la Fuente H, Jorge I, Sáiz M, et al. Targeting L-type amino acid transporter 1 in innate and adaptive T cells efficiently controls skin inflammation. J Allergy Clin Immunol. 2020;145:199-214.e11 pubmed publisher
Zhang H, Carnevale G, Polese B, Simard M, Thurairajah B, Khan N, et al. CD109 Restrains Activation of Cutaneous IL-17-Producing γδ T Cells by Commensal Microbiota. Cell Rep. 2019;29:391-405.e5 pubmed publisher
Godwin M, Reeder K, Garth J, Blackburn J, Jones M, Yu Z, et al. IL-1RA regulates immunopathogenesis during fungal-associated allergic airway inflammation. JCI Insight. 2019;4: pubmed publisher
Luck H, Khan S, Kim J, Copeland J, Revelo X, Tsai S, et al. Gut-associated IgA+ immune cells regulate obesity-related insulin resistance. Nat Commun. 2019;10:3650 pubmed publisher
Mathur A, Zirak B, Boothby I, Tan M, Cohen J, Mauro T, et al. Treg-Cell Control of a CXCL5-IL-17 Inflammatory Axis Promotes Hair-Follicle-Stem-Cell Differentiation During Skin-Barrier Repair. Immunity. 2019;50:655-667.e4 pubmed publisher
Jin C, Lagoudas G, Zhao C, Bullman S, Bhutkar A, Hu B, et al. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells. Cell. 2019;176:998-1013.e16 pubmed publisher
Kobayashi T, Voisin B, Kim D, Kennedy E, Jo J, Shih H, et al. Homeostatic Control of Sebaceous Glands by Innate Lymphoid Cells Regulates Commensal Bacteria Equilibrium. Cell. 2019;176:982-997.e16 pubmed publisher
Medler T, Murugan D, Horton W, Kumar S, Cotechini T, Forsyth A, et al. Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy. Cancer Cell. 2018;34:561-578.e6 pubmed publisher
Bahmani B, Uehara M, Jiang L, Ordikhani F, Banouni N, Ichimura T, et al. Targeted delivery of immune therapeutics to lymph nodes prolongs cardiac allograft survival. J Clin Invest. 2018;128:4770-4786 pubmed publisher
Kosack L, Gawish R, Lercher A, Vilagos B, Hladik A, Lakovits K, et al. The lipid-sensor TREM2 aggravates disease in a model of LCMV-induced hepatitis. Sci Rep. 2017;7:11289 pubmed publisher
Schofield L, Ioannidis L, Karl S, Robinson L, Tan Q, Poole D, et al. Synergistic effect of IL-12 and IL-18 induces TIM3 regulation of ?? T cell function and decreases the risk of clinical malaria in children living in Papua New Guinea. BMC Med. 2017;15:114 pubmed publisher
Babb R, Chen A, Hirst T, Kara E, McColl S, Ogunniyi A, et al. Intranasal vaccination with γ-irradiated Streptococcus pneumoniae whole-cell vaccine provides serotype-independent protection mediated by B-cells and innate IL-17 responses. Clin Sci (Lond). 2016;130:697-710 pubmed publisher
Barrigan L, Tuladhar S, Brunton J, Woolard M, Chen C, Saini D, et al. Infection with Francisella tularensis LVS clpB leads to an altered yet protective immune response. Infect Immun. 2013;81:2028-42 pubmed publisher
Van Belle A, de Heusch M, Lemaire M, Hendrickx E, Warnier G, Dunussi Joannopoulos K, et al. IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice. J Immunol. 2012;188:462-9 pubmed publisher
Stadanlick J, Zhang Z, Lee S, Hemann M, Biery M, Carleton M, et al. Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors. J Immunol. 2011;187:664-75 pubmed publisher
Kasten K, Prakash P, Unsinger J, Goetzman H, England L, Cave C, et al. Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infect Immun. 2010;78:4714-22 pubmed publisher
product information
Antigen :
TCR gamma/delta
Apps. Abbrev. :
Flow Cytometry
Cat # :
118118
Clone :
GL3
Item :
PerCP/Cyanine5.5 anti-mouse TCR γ/δ
Isotype :
Armenian Hamster IgG
Other Names :
T cell receptor γ/δ
Size :
100 μg
Price (USD) :
323 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
PERCP_CYANINE5.5
Immunogen :
C57BL/6J intraepithelial lymphocytes
Application Notes :
The GL3 antibody has been shown to be useful in identifying / T cells by flow cytometry and immunohistochemistry and depleting / T cells in vivo . Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemistry of acetone-fixed frozen sections 2,6 , and in vivo depletion of / T cells 3-5 .
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA