LEAF™ Purified anti-mouse TCR γ/δ | BioLegend 118114 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

BioLegend

other brands :

Babco, Signet, Sternberger Monoclonals, Senetek, Covance

product type :

antibody

product name :

LEAF™ Purified anti-mouse TCR γ/δ

catalog :

118114

quantity :

500 μg

price :

275 USD

clonality :

monoclonal

host :

hamsters

conjugate :

nonconjugated

clone name :

GL3

reactivity :

mouse

application :

immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section

citations: 17

Published Application/Species/Sample/Dilution	Reference
flow cytometry; mouse; loading ...; fig ex5c	He S, Kahles F, Rattik S, Nairz M, McAlpine C, Anzai A, et al. Gut intraepithelial T cells calibrate metabolism and accelerate cardiovascular disease. Nature. 2019;566:115-119 pubmed publisher
flow cytometry; mouse; loading ...; fig s2a	Martins J, Andoniou C, Fleming P, Kuns R, Schuster I, Voigt V, et al. Strain-specific antibody therapy prevents cytomegalovirus reactivation after transplantation. Science. 2019;363:288-293 pubmed publisher
flow cytometry; mouse; loading ...; fig 6b	Er J, Koean R, Ding J. Loss of T-bet confers survival advantage to influenza-bacterial superinfection. EMBO J. 2019;38: pubmed publisher
flow cytometry; mouse; loading ...; fig 5d	Vuckovic S, Minnie S, Smith D, Gartlan K, Watkins T, Markey K, et al. Bone marrow transplantation generates T cell-dependent control of myeloma in mice. J Clin Invest. 2019;129:106-121 pubmed publisher
flow cytometry; mouse; loading ...; fig s4b	Nusse Y, Savage A, Marangoni P, Rosendahl Huber A, Landman T, De Sauvage F, et al. Parasitic helminths induce fetal-like reversion in the intestinal stem cell niche. Nature. 2018;559:109-113 pubmed publisher
flow cytometry; mouse; loading ...; fig 4a	Varelias A, Bunting M, Ormerod K, Koyama M, Olver S, Straube J, et al. Recipient mucosal-associated invariant T cells control GVHD within the colon. J Clin Invest. 2018;128:1919-1936 pubmed publisher
flow cytometry; mouse; loading ...; fig s4a	Prado C, Gaiazzi M, Gonzalez H, Ugalde V, Figueroa A, Osorio Barrios F, et al. Dopaminergic Stimulation of Myeloid Antigen-Presenting Cells Attenuates Signal Transducer and Activator of Transcription 3-Activation Favouring the Development of Experimental Autoimmune Encephalomyelitis. Front Immunol. 2018;9:571 pubmed publisher
flow cytometry; mouse; loading ...; fig s12a	Sui P, Wiesner D, Xu J, Zhang Y, Lee J, Van Dyken S, et al. Pulmonary neuroendocrine cells amplify allergic asthma responses. Science. 2018;360: pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Fahl S, Coffey F, Kain L, Zarin P, Dunbrack R, Teyton L, et al. Role of a selecting ligand in shaping the murine γδ-TCR repertoire. Proc Natl Acad Sci U S A. 2018;115:1889-1894 pubmed publisher
flow cytometry; mouse; loading ...; fig 1a	Muro R, Nitta T, Nakano K, Okamura T, Takayanagi H, Suzuki H. γδTCR recruits the Syk/PI3K axis to drive proinflammatory differentiation program. J Clin Invest. 2018;128:415-426 pubmed publisher
flow cytometry; mouse; loading ...; fig s5d	Wallrapp A, Riesenfeld S, Burkett P, Abdulnour R, Nyman J, Dionne D, et al. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature. 2017;549:351-356 pubmed publisher
flow cytometry; mouse; loading ...; fig 3a	Muschaweckh A, Petermann F, Korn T. IL-1? and IL-23 Promote Extrathymic Commitment of CD27+CD122- ?? T Cells to ??T17 Cells. J Immunol. 2017;199:2668-2679 pubmed publisher
flow cytometry; mouse; fig s3b	Tripathi D, Venkatasubramanian S, Cheekatla S, Paidipally P, Welch E, Tvinnereim A, et al. A TLR9 agonist promotes IL-22-dependent pancreatic islet allograft survival in type 1 diabetic mice. Nat Commun. 2016;7:13896 pubmed publisher
immunocytochemistry; mouse	Strid J, Sobolev O, Zafirova B, Polic B, Hayday A. The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy. Science. 2011;334:1293-7 pubmed publisher
	Van Belle A, de Heusch M, Lemaire M, Hendrickx E, Warnier G, Dunussi Joannopoulos K, et al. IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice. J Immunol. 2012;188:462-9 pubmed publisher
	Stadanlick J, Zhang Z, Lee S, Hemann M, Biery M, Carleton M, et al. Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors. J Immunol. 2011;187:664-75 pubmed publisher
	Kasten K, Prakash P, Unsinger J, Goetzman H, England L, Cave C, et al. Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infect Immun. 2010;78:4714-22 pubmed publisher

product information

Antigen :

TCR gamma/delta

Apps. Abbrev. :

Flow Cytometry, IHC-F, IP

Cat # :

118114

Clone :

GL3

Item :

LEAF™ Purified anti-mouse TCR γ/δ

Isotype :

Armenian Hamster IgG

Other Names :

T cell receptor γ/δ

Size :

500 μg

Price (USD) :

275 USD

Reactivity :

Mouse

Clonality :

Monoclonal

Host :

Armenian Hamster

Conjugate/Tag/Label :

LEAF

Immunogen :

C57BL/6J intraepithelial lymphocytes

Application Notes :

The GL3 antibody has been shown to be useful in identifying γ/δ T cells by flow cytometry and immunohistochemistry and depleting γ/δ T cells in vivo . Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemistry of acetone-fixed frozen sections 2,6 , and in vivo depletion of γ/δ T cells 3-5 .