product summary
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company name :
BioLegend
other brands :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
product type :
antibody
product name :
Biotin anti-mouse TCR γ/δ
catalog :
118103
quantity :
50 μg
price :
94 USD
clonality :
monoclonal
host :
hamsters
conjugate :
biotin
clone name :
GL3
reactivity :
mouse
application :
immunocytochemistry, flow cytometry
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • flow cytometry; mouse
Mathews J, Williams A, Brand J, Wurmbrand A, Chen L, Ninin F, et al. γδ T cells are required for pulmonary IL-17A expression after ozone exposure in mice: role of TNFα. PLoS ONE. 2014;9:e97707 pubmed publisher
  • immunocytochemistry; mouse
Strid J, Sobolev O, Zafirova B, Polic B, Hayday A. The intraepithelial T cell response to NKG2D-ligands links lymphoid stress surveillance to atopy. Science. 2011;334:1293-7 pubmed publisher
Giannou A, Kempski J, Shiri A, L xfc cke J, Zhang T, Zhao L, et al. Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22. Immunity. 2023;56:125-142.e12 pubmed publisher
Koizumi M, Kama Y, Hirano K, Endo Y, Tanaka T, Hozumi K, et al. Transcription factor Zbtb1 interacts with bridging factor Lmo2 and maintains the T-lineage differentiation capacity of lymphoid progenitor cells. J Biol Chem. 2022;298:102506 pubmed publisher
Higa T, Okita Y, Matsumoto A, Nakayama S, Oka T, Sugahara O, et al. Spatiotemporal reprogramming of differentiated cells underlies regeneration and neoplasia in the intestinal epithelium. Nat Commun. 2022;13:1500 pubmed publisher
Fujimori S, Ohigashi I, Abe H, Matsushita Y, Katagiri T, Taketo M, et al. Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development. elife. 2022;11: pubmed publisher
Wang T, Lv C, Hu F, Liu L, Wang J. Two-step protocol for regeneration of immunocompetent T cells from mouse pluripotent stem cells. Blood Sci. 2020;2:79-88 pubmed publisher
Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, et al. Mitochondrial C1qbp promotes differentiation of effector CD8+ T cells via metabolic-epigenetic reprogramming. Sci Adv. 2021;7:eabk0490 pubmed publisher
Paiva R, Ramos C, Azenha S, Alves C, Basto A, Graca L, et al. Peptidylprolyl isomerase C (Ppic) regulates invariant Natural Killer T cell (iNKT) differentiation in mice. Eur J Immunol. 2021;51:1968-1979 pubmed publisher
Grigsby S, Friedman A, Chase J, Waas B, Ropa J, Serio J, et al. Elucidating the Importance of DOT1L Recruitment in MLL-AF9 Leukemia and Hematopoiesis. Cancers (Basel). 2021;13: pubmed publisher
Zeis P, Lian M, Fan X, Herman J, Hernandez D, Gentek R, et al. In Situ Maturation and Tissue Adaptation of Type 2 Innate Lymphoid Cell Progenitors. Immunity. 2020;53:775-792.e9 pubmed publisher
He J, Yang Q, Xiao Q, Lei A, Li X, Zhou P, et al. IRF-7 Is a Critical Regulator of Type 2 Innate Lymphoid Cells in Allergic Airway Inflammation. Cell Rep. 2019;29:2718-2730.e6 pubmed publisher
Nagashima H, Mahlakõiv T, Shih H, Davis F, Meylan F, Huang Y, et al. Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation. Immunity. 2019;51:682-695.e6 pubmed publisher
Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, et al. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. EMBO J. 2019;38: pubmed publisher
Johnson J, Georgakilas G, Petrovic J, Kurachi M, Cai S, Harly C, et al. Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells. Immunity. 2018;48:243-257.e10 pubmed publisher
Li Q, Li D, Zhang X, Wan Q, Zhang W, Zheng M, et al. E3 Ligase VHL Promotes Group 2 Innate Lymphoid Cell Maturation and Function via Glycolysis Inhibition and Induction of Interleukin-33 Receptor. Immunity. 2018;48:258-270.e5 pubmed publisher
Thelin M, Kissler S, Vigneault F, Watters A, White D, Koshy S, et al. In Vivo Enrichment of Diabetogenic T Cells. Diabetes. 2017;66:2220-2229 pubmed publisher
Akkaya B, Holstein A, Isaac C, Maz M, Glass D, Shevach E, et al. Ex-vivo iTreg differentiation revisited: Convenient alternatives to existing strategies. J Immunol Methods. 2017;441:67-71 pubmed publisher
Galle Treger L, Suzuki Y, Patel N, Sankaranarayanan I, Aron J, Maazi H, et al. Nicotinic acetylcholine receptor agonist attenuates ILC2-dependent airway hyperreactivity. Nat Commun. 2016;7:13202 pubmed publisher
Van Belle A, de Heusch M, Lemaire M, Hendrickx E, Warnier G, Dunussi Joannopoulos K, et al. IL-22 is required for imiquimod-induced psoriasiform skin inflammation in mice. J Immunol. 2012;188:462-9 pubmed publisher
Stadanlick J, Zhang Z, Lee S, Hemann M, Biery M, Carleton M, et al. Developmental arrest of T cells in Rpl22-deficient mice is dependent upon multiple p53 effectors. J Immunol. 2011;187:664-75 pubmed publisher
Kasten K, Prakash P, Unsinger J, Goetzman H, England L, Cave C, et al. Interleukin-7 (IL-7) treatment accelerates neutrophil recruitment through gamma delta T-cell IL-17 production in a murine model of sepsis. Infect Immun. 2010;78:4714-22 pubmed publisher
Okamura T, Fujio K, Shibuya M, Sumitomo S, Shoda H, Sakaguchi S, et al. CD4+CD25-LAG3+ regulatory T cells controlled by the transcription factor Egr-2. Proc Natl Acad Sci U S A. 2009;106:13974-9 pubmed publisher
product information
Antigen :
TCR gamma/delta
Apps. Abbrev. :
FC
Cat # :
118103
Clone :
GL3
Item :
Biotin anti-mouse TCR γ/δ
Isotype :
Armenian Hamster IgG
Other Names :
T cell receptor γ/δ
Size :
50 μg
Price (USD) :
94 USD
Reactivity :
Mouse
Clonality :
Monoclonal
Host :
Armenian Hamster
Conjugate/Tag/Label :
BIOTIN
Immunogen :
C57BL/6J intraepithelial lymphocytes
Application Notes :
The GL3 antibody has been shown to be useful in identifying γ/δ T cells by flow cytometry and immunohistochemistry and depleting γ/δ T cells in vivo. Additional reported applications (for the relevant formats) include: immunoprecipitation^1, immunohistochemistry of acetone-fixed frozen sections^2,6, and in vivo depletion of γ/δ T cells^3-5.;
more info or order :
company information
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
headquarters: USA